Protein: UHRF1
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)

Gene: UHRF1
Organism: Mus musculus
Interactions: 23
UniProt ID: Q8VDF2

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000792 - heterochromatin
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533917

DNMT1
DNA

6

11

Small-scale

0.941

High

1257477

UHRF1
E3 ubiquitin-protein ligase UHRF1

2

14

Small-scale

0.778

High

952760

H33
Histone H3.3

2

20

Small-scale

0.727

High

500579

H2B1F
Histone H2B type 1-F/J/L

1

20

Small-scale

0.692

High

1246719

DPPA3
Developmental pluripotency-associated protein 3

2

2

Small-scale

0.619

High

1257482

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

9

Small-scale

0.618

High

1257481

Q921K2
Poly [ADP-ribose] polymerase

2

15

Small-scale

0.584

High

1206768

EME1
Crossover junction endonuclease EME1

1

1

Small-scale

0.573

High

83335

H2A1B
Histone H2A type 1-B

1

14

Small-scale

0.527

High

1257479

MUS81
Crossover junction endonuclease MUS81

1

1

Small-scale

0.501

High

638628

RBTN2
Rhombotin-2

1

12

Small-scale

0.481

High

291736

DNM3A
DNA

1

8

Small-scale

0.479

High

644507

TWST1
Twist-related protein 1

1

6

High-throughput

0.479

High

786660

STA5A
Signal transducer and activator of transcription 5A

1

2

Small-scale

0.479

High

964616

TOP2A
DNA topoisomerase 2-alpha

1

8

Small-scale

0.479

High

1113214

TET1
Methylcytosine dioxygenase TET1

1

1

Small-scale

0.479

High

1143873

ATM
Serine-protein kinase ATM

1

9

Small-scale

0.479

High

1145245

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

12

High-throughput

0.479

High

1145442

TOP2B
DNA topoisomerase 2-beta

1

9

Small-scale

0.479

High

1194649

NANOG
Homeobox protein NANOG

1

14

High-throughput

0.479

High

1257478

RCC1
Regulator of chromosome condensation

1

1

Small-scale

0.479

High

1257480

SP16H
FACT complex subunit SPT16

1

4

Small-scale

0.479

High


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Last updated: 15 Jul 2024