Protein: KCNJ5
G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)

Gene: KCNJ5
Organism: Homo sapiens
Interactions: 21
UniProt ID: P48544

Gene Ontology (top 5):
GO:0005242 - inward rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0008076 - voltage-gated potassium channel complex
GO:0015467 - G-protein activated inward rectifier potassium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873875

KCNJ3
G protein-activated inward rectifier potassium channel 1

4

15

Small-scale

0.896

High

873883

KCJ15
ATP-sensitive inward rectifier potassium channel 15

2

14

High-throughput

0.783

High

873884

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

2

2

High-throughput

0.726

High

84399

KCJ18
Inward rectifier potassium channel 18

1

15

High-throughput

0.618

High

458327

ADRB2
Beta-2 adrenergic receptor

2

2

Small-scale

0.614

High

619008

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

2

0

High-throughput

0.602

High

873881

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.602

High

873882

PKP4
Plakophilin-4

2

0

High-throughput

0.602

High

873886

LANC2
LanC-like protein 2

2

0

High-throughput

0.602

High

870037

KCNJ6
G protein-activated inward rectifier potassium channel 2

1

15

High-throughput

0.575

High

873877

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.536

High

873885

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

2

High-throughput

0.489

High

572424

DRD2
D(2) dopamine receptor

1

8

Small-scale

0.479

High

641881

DRD4
D(4) dopamine receptor

1

8

Small-scale

0.479

High

215745

ERI3
ERI1 exoribonuclease 3

2

0

High-throughput

0.328

High

334156

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

0

High-throughput

0.328

High

873879

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

0

High-throughput

0.328

High

873880

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

2

0

High-throughput

0.328

High

873887

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

2

0

High-throughput

0.328

High

873876

PRI1
DNA primase small subunit

1

0

High-throughput

0.279

Low

873878

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025