Protein: LEM2
Lap-Emerin-Man domain protein 2 (LEM domain protein 2)

Gene: LEM2
Organism: Schizosaccharomyces pombe 972h-
Interactions: 143
UniProt ID: Q10109

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0003690 - double-stranded DNA binding
GO:0005635 - nuclear envelope
GO:0005637 - nuclear inner membrane
GO:0005721 - pericentric heterochromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

224149

BQT4
Bouquet formation protein 4

3

1

Small-scale

0.642

High

999963

SAD1
Spindle pole body-associated protein sad1

3

1

Small-scale

0.639

High

142385

IINMP
Integral inner nuclear membrane protein ima1

2

1

Small-scale

0.584

High

953490

MU154
Meiotically up-regulated gene 154 protein

2

0

Small-scale

0.561

High

945028

VTC4
Vacuolar transporter chaperone complex subunit 4

2

2

Small-scale

0.535

High

223547

LAC1
Sphingosine N-acyltransferase lac1

1

3

High-throughput

0.481

High

252138

PMP31
Plasma membrane proteolipid 31

1

1

High-throughput

0.481

High

953453

DGK1
CTP-dependent diacylglycerol kinase 1

1

1

High-throughput

0.481

High

998272

ERG24
Delta(14)-sterol reductase erg24

1

2

High-throughput

0.481

High

223895

IMB4
Probable importin subunit beta-4

1

2

Small-scale

0.479

High

251577

IMB3
Importin subunit beta-3

1

1

Small-scale

0.479

High

736950

BIP
Endoplasmic reticulum chaperone BiP

1

3

Small-scale

0.479

High

771121

CSK2A
Casein kinase II subunit alpha

1

1

Small-scale

0.479

High

142585

MUG61
Meiotically up-regulated gene 61 protein

1

0

High-throughput

0.460

High

144999

MUG69
SRP-independent targeting protein 2 homolog

1

0

High-throughput

0.460

High

223872

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.460

High

251616

BQT3
Bouquet formation protein 3

1

0

High-throughput

0.460

High

1013493

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

High-throughput

0.460

High

1013498

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.460

High

1013501

MUG31
Meiotically up-regulated gene 31 protein

1

0

High-throughput

0.460

High

1013503

SPO7
Sporulation-specific protein spo7

1

0

High-throughput

0.460

High

1013508

DYLT
Dynein light chain Tctex-type

1

0

High-throughput

0.460

High

1013509

YOP1
Protein yop1

1

0

High-throughput

0.460

High

223723

IMA3
Probable importin c550.11

1

0

Small-scale

0.458

High

1013485

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

0

Small-scale

0.458

High

142690

VTC2
Vacuolar transporter chaperone complex subunit 2

1

2

High-throughput

0.439

High

142892

SEC62
Translocation protein sec62

1

1

High-throughput

0.439

High

143396

SCS7
Ceramide very long chain fatty acid hydroxylase scs7

1

3

High-throughput

0.439

High

143578

BET1
Protein transport protein bet1

1

1

High-throughput

0.439

High

143632

RBX1
RING-box protein pip1

1

1

High-throughput

0.439

High

145059

TVP15
Golgi apparatus membrane protein tvp15

1

1

High-throughput

0.439

High

145197

PSA6
Probable proteasome subunit alpha type-6

1

1

High-throughput

0.439

High

193851

UBC6
Ubiquitin-conjugating enzyme E2 6

1

1

High-throughput

0.439

High

194015

YFH5
Uncharacterized membrane protein C23A1.05

1

1

High-throughput

0.439

High

194824

YBA9
Uncharacterized protein C119.09c

1

1

High-throughput

0.439

High

194833

YBAG
Uncharacterized protein C119.16c

1

1

High-throughput

0.439

High

195027

SC61B
Protein transport protein sec61 subunit beta

1

1

High-throughput

0.439

High

223521

FNX2
Vacuolar membrane amino acid uptake transporter fnx2

1

1

High-throughput

0.439

High

223631

YCCC
Uncharacterized protein C1795.12c

1

1

High-throughput

0.439

High

251702

SURF4
Surfeit locus protein 4 homolog

1

1

High-throughput

0.439

High

251810

YEA4
UDP-N-acetylglucosamine transporter yea4

1

4

High-throughput

0.439

High

293173

YIP1
Protein transport protein yip1

1

1

High-throughput

0.439

High

293297

CYB51
Probable cytochrome b5 1

1

2

High-throughput

0.439

High

293563

PSA1
Probable proteasome subunit alpha type-1

1

2

High-throughput

0.439

High

293572

YQ13
ER membrane protein complex subunit 4

1

1

High-throughput

0.439

High

293715

PSA2
Probable proteasome subunit alpha type-2

1

1

High-throughput

0.439

High

734289

ERG4
Delta(24(24(1)))-sterol reductase

1

2

High-throughput

0.439

High

945007

VTI1
Vesicle transport v-SNARE protein vti1

1

1

High-throughput

0.439

High

945141

LAG1
Sphingosine N-acyltransferase lag1

1

3

High-throughput

0.439

High

953428

YIF1
Protein transport protein yif1

1

1

High-throughput

0.439

High

965000

SAR1
Small COPII coat GTPase sar1

1

4

High-throughput

0.439

High

999714

PSA3
Probable proteasome subunit alpha type-3

1

1

High-throughput

0.439

High

999756

AKR1
Palmitoyltransferase akr1

1

3

High-throughput

0.439

High

999998

GOS1
Protein transport protein gos1

1

1

High-throughput

0.439

High

1013483

EMA19
Efficient mitochondria targeting-associated protein 19

1

1

High-throughput

0.439

High

1013484

AREH1
Probable sterol O-acyltransferase 1

1

1

High-throughput

0.439

High

1013486

YDE2
Uncharacterized protein C12B10.02c

1

1

High-throughput

0.439

High

1013488

HUT1
UDP-galactose transporter homolog 1

1

3

High-throughput

0.439

High

1013499

VTC1
Vacuolar transporter chaperone complex subunit 1

1

2

High-throughput

0.439

High

1013502

CYB52
Probable cytochrome b5 2

1

2

High-throughput

0.439

High

1013511

YIY4
Uncharacterized transporter C22F8.04

1

1

High-throughput

0.439

High

1013516

COX10
Protoheme IX farnesyltransferase, mitochondrial

1

1

High-throughput

0.439

High

142023

YNF5
Uncharacterized J domain-containing protein C17A3.05c

1

4

Small-scale

0.437

High

224109

RL7C
Large ribosomal subunit protein uL30C

1

2

Small-scale

0.437

High

622909

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

Small-scale

0.437

High

788728

RAD25
Checkpoint signal transducer rad25

1

2

Small-scale

0.437

High

945025

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

Small-scale

0.437

High

945176

RL6
Large ribosomal subunit protein eL6

1

1

Small-scale

0.437

High

999912

PYR1
Multifunctional protein ura1

1

1

Small-scale

0.437

High

1013476

GCN1
eIF-2-alpha kinase activator gcn1

1

4

Small-scale

0.437

High

1013489

MCD4
GPI ethanolamine phosphate transferase 1

1

1

Small-scale

0.437

High

293575

ACO1
Probable acyl-CoA desaturase

2

0

Small-scale

0.306

High

87140

YKQP
Uncharacterized membrane protein C688.16

1

0

High-throughput

0.251

Low

87152

VMA21
Vacuolar ATPase assembly integral membrane protein vma21

1

0

High-throughput

0.251

Low

102122

YND9
Putative uncharacterized protein C30B4.09

1

0

High-throughput

0.251

Low

102129

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.251

Low

102132

KISH
Protein kish

1

0

High-throughput

0.251

Low

102136

TAM14
Protein tam14

1

0

High-throughput

0.251

Low

142888

USE1
Protein transport protein use1

1

0

High-throughput

0.251

Low

144459

TGL4
Triacylglycerol lipase ptl2

1

0

High-throughput

0.251

Low

193738

YEKI
Uncharacterized WD repeat-containing protein C4F10.18

1

0

High-throughput

0.251

Low

194876

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

High-throughput

0.251

Low

194911

PHO88
SRP-independent targeting protein 3 homolog

1

0

High-throughput

0.251

Low

195055

YGV4
Uncharacterized protein C354.04

1

0

High-throughput

0.251

Low

223512

DEGS
Sphingolipid delta(4)-desaturase

1

0

High-throughput

0.251

Low

223605

YJMB
ER membrane protein complex subunit 6

1

0

High-throughput

0.251

Low

223960

SCS2
Vesicle-associated membrane protein-associated protein scs2

1

0

High-throughput

0.251

Low

251445

ATC9
Probable cation-transporting ATPase C1672.11c

1

0

High-throughput

0.251

Low

252606

VPS25
Vacuolar protein-sorting-associated protein 25

1

0

High-throughput

0.251

Low

252641

YJZI
Uncharacterized membrane protein C338.18

1

0

High-throughput

0.251

Low

292981

SEC13
Protein transport protein sec13

1

0

High-throughput

0.251

Low

293363

YHKH
Uncharacterized membrane protein C660.17c

1

0

High-throughput

0.251

Low

293447

YFFH
Uncharacterized derlin-like protein C1687.17c

1

0

High-throughput

0.251

Low

293586

UFE1
Syntaxin ufe1

1

0

High-throughput

0.251

Low

293878

DPM3
Dolichol-phosphate mannosyltransferase subunit 3

1

0

High-throughput

0.251

Low

293943

GPC1
Glycerophosphocholine acyltransferase 1

1

0

High-throughput

0.251

Low

293956

PDAT
Phospholipid:diacylglycerol acyltransferase

1

0

High-throughput

0.251

Low

478651

YKV6
Uncharacterized protein C959.06c

1

0

High-throughput

0.251

Low

953193

MAM4
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.251

Low

953200

GMS1
UDP-galactose transporter

1

0

High-throughput

0.251

Low

999852

SFT1
Protein transport protein sft1

1

0

High-throughput

0.251

Low

1013481

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.251

Low

1013487

RNK
V-type proton ATPase subunit f

1

0

High-throughput

0.251

Low

1013490

OST4
Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase 4 kDa subunit

1

0

High-throughput

0.251

Low

1013491

IVN1
Phospholipid-transporting ATPase accessory subunit ivn1

1

0

High-throughput

0.251

Low

1013492

ALG2
Alpha-1,3/1,6-mannosyltransferase alg2

1

0

High-throughput

0.251

Low

1013494

ERG1
Squalene epoxidase erg1

1

0

High-throughput

0.251

Low

1013495

MIM1
Mitochondrial import protein 1

1

0

High-throughput

0.251

Low

1013496

YLZ7
Uncharacterized GPI-anchored protein SPAC750.07c

1

0

High-throughput

0.251

Low

1013500

GGT1
Glutathione hydrolase proenzyme 1

1

0

High-throughput

0.251

Low

1013504

CTR6
Copper transport protein ctr6

1

0

High-throughput

0.251

Low

1013505

INP2
Inheritance of peroxisomes protein 2

1

0

High-throughput

0.251

Low

1013507

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.251

Low

1013512

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.251

Low

1013513

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.251

Low

1013514

SEC22
Protein transport protein sec22

1

0

High-throughput

0.251

Low

1013515

INS1
INSIG family protein

1

0

High-throughput

0.251

Low

140987

DED1
ATP-dependent RNA helicase ded1

1

0

Small-scale

0.249

Low

142280

RL8
Large ribosomal subunit protein eL8

1

0

Small-scale

0.249

Low

143303

ERG5
C-22 sterol desaturase ERG5

1

0

Small-scale

0.249

Low

194802

YBN1
Putative inorganic phosphate transporter C8E4.01c

1

0

Small-scale

0.249

Low

194906

PFKA
ATP-dependent 6-phosphofructokinase

1

0

Small-scale

0.249

Low

223796

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1

1

0

Small-scale

0.249

Low

224084

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

0

Small-scale

0.249

Low

251171

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.249

Low

251318

TCPG
T-complex protein 1 subunit gamma

1

0

Small-scale

0.249

Low

251923

CHO2
Phosphatidylethanolamine N-methyltransferase

1

0

Small-scale

0.249

Low

252209

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

292866

YGX1
UPF0674 endoplasmic reticulum membrane protein C2G5.01

1

0

Small-scale

0.249

Low

293163

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3

1

0

Small-scale

0.249

Low

293535

YN67
Putative enoyl reductase C646.07c

1

0

Small-scale

0.249

Low

334003

ADH
Alcohol dehydrogenase

1

0

Small-scale

0.249

Low

727471

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.249

Low

784548

BFR1
Brefeldin A resistance protein

1

0

Small-scale

0.249

Low

999860

CP51
Lanosterol 14-alpha demethylase erg11

1

0

Small-scale

0.249

Low

999906

RS3A1
Small ribosomal subunit protein eS1A

1

0

Small-scale

0.249

Low

1000036

MET10
Probable sulfite reductase [NADPH] flavoprotein component

1

0

Small-scale

0.249

Low

1013468

YAOE
Uncharacterized protein C11D3.14c

1

0

Small-scale

0.249

Low

1013482

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.249

Low

1013497

MPCP
Probable mitochondrial phosphate carrier protein

1

0

Small-scale

0.249

Low

1013506

APE1
Aminopeptidase 1

1

0

Small-scale

0.249

Low

1013510

FAS1
Fatty acid synthase subunit beta

1

0

Small-scale

0.249

Low

1013517

HOSM
Homocitrate synthase, mitochondrial

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024