Protein: RRP4
Exosome complex component rrp4 (Ribosomal RNA-processing protein 4)

Gene: RRP4
Organism: Schizosaccharomyces pombe 972h-
Interactions: 229
UniProt ID: Q09704

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000785 - chromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

999778

RRP43
Exosome complex component rrp43

2

20

Small-scale

0.754

High

740322

DIS3
Exosome complex exonuclease dis3

3

5

Small-scale

0.640

High

143507

RRP40
Exosome complex component rrp40

1

5

High-throughput

0.618

High

194783

RRP41
Exosome complex component ski6

1

20

High-throughput

0.618

High

194809

RRP46
Exosome complex component rrp46

1

17

High-throughput

0.618

High

223964

RRP42
Exosome complex component rrp42

1

20

High-throughput

0.618

High

252127

RRP5
rRNA biogenesis protein rrp5

1

1

High-throughput

0.618

High

252321

RRP45
Exosome complex component rrp45

1

20

High-throughput

0.618

High

999811

MTR3
Exosome complex component mtr3

1

20

High-throughput

0.618

High

144279

YEAB
Uncharacterized protein UNK4.11c

1

0

High-throughput

0.586

High

880371

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.586

High

999827

RED1
NURS complex subunit red1

2

1

High-throughput

0.584

High

145295

YFPE
Uncharacterized protein C7D4.14c

2

0

High-throughput

0.559

High

140985

DED1
ATP-dependent RNA helicase ded1

1

1

High-throughput

0.479

High

142021

MS116
ATP-dependent RNA helicase mss116, mitochondrial

1

4

High-throughput

0.479

High

143129

YE02
Uncharacterized helicase C17H9.02

1

5

High-throughput

0.479

High

143309

IMP4
U3 small nucleolar ribonucleoprotein protein imp4

1

1

High-throughput

0.479

High

143519

MPP10
U3 small nucleolar ribonucleoprotein protein mpp10

1

1

High-throughput

0.479

High

143963

SGD1
Suppressor of glycerol defect protein 1

1

3

High-throughput

0.479

High

144247

UTP21
U3 small nucleolar RNA-associated protein 21 homolog

1

3

High-throughput

0.479

High

145116

MTR4
ATP-dependent RNA helicase mtr4

1

5

High-throughput

0.479

High

145411

YB7A
Uncharacterized AAA domain-containing protein C16E9.10c

1

2

High-throughput

0.479

High

145488

RM07
Large ribosomal subunit protein uL5m

1

1

High-throughput

0.479

High

145493

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

145582

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.479

High

145828

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

194028

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

194794

FCF2
rRNA-processing protein fcf2

1

1

High-throughput

0.479

High

195014

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

195116

NOP14
Probable nucleolar complex protein 14

1

1

High-throughput

0.479

High

223684

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

223736

CSL4
Exosome complex component csl4

1

3

High-throughput

0.479

High

223780

HSP72
Probable heat shock protein ssa2

1

2

High-throughput

0.479

High

223831

UTP20
U3 small nucleolar RNA-associated protein 20

1

1

High-throughput

0.479

High

223867

YBB9
Uncharacterized protein C13G1.09

1

1

High-throughput

0.479

High

223878

DBP9
ATP-dependent RNA helicase dbp9

1

1

High-throughput

0.479

High

223981

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

224108

RL7C
Large ribosomal subunit protein uL30C

1

2

High-throughput

0.479

High

224183

DBP7
ATP-dependent RNA helicase dbp7

1

3

High-throughput

0.479

High

251225

RL5B
Large ribosomal subunit protein uL18B

1

1

High-throughput

0.479

High

251312

DCA13
Protein sof1

1

2

High-throughput

0.479

High

251392

MAK5
ATP-dependent RNA helicase mak5

1

2

High-throughput

0.479

High

251466

UBP16
Probable ubiquitin carboxyl-terminal hydrolase 16

1

1

High-throughput

0.479

High

251549

YQC7
Exosome complex protein C1739.07

1

1

High-throughput

0.479

High

251678

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

251916

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.479

High

252234

NOL10
Ribosome biogenesis protein enp2 homolog

1

1

High-throughput

0.479

High

252263

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

293199

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.479

High

293379

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.479

High

293552

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

293912

BMS1
Ribosome biogenesis protein bms1

1

1

High-throughput

0.479

High

293920

NOG1
Probable nucleolar GTP-binding protein 1

1

1

High-throughput

0.479

High

293945

UTP22
U3 small nucleolar RNA-associated protein 22

1

1

High-throughput

0.479

High

293959

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

294054

RS15A
Small ribosomal subunit protein uS19A

1

2

High-throughput

0.479

High

448925

H4
Histone H4

1

1

High-throughput

0.479

High

478692

TLH1
ATP-dependent DNA helicase tlh1

1

5

High-throughput

0.479

High

548210

RPA1
DNA-directed RNA polymerase I subunit rpa1

1

2

High-throughput

0.479

High

572531

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.479

High

632603

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.479

High

656933

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

727470

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

736904

RPB1
DNA-directed RNA polymerase II subunit rpb1

1

2

High-throughput

0.479

High

884436

RL28B
Large ribosomal subunit protein uL15B

1

1

High-throughput

0.479

High

945044

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.479

High

945094

RL26
Large ribosomal subunit protein uL24

1

1

High-throughput

0.479

High

945108

IF4E1
Eukaryotic translation initiation factor 4E-1

1

1

High-throughput

0.479

High

953330

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

953401

YDM6
Uncharacterized protein C57A7.06

1

1

High-throughput

0.479

High

975928

PRH1
Probable ATP-dependent RNA helicase prh1

1

1

High-throughput

0.479

High

998439

MLO3
mRNA export protein mlo3

1

2

High-throughput

0.479

High

999760

DBP10
ATP-dependent RNA helicase dbp10

1

1

High-throughput

0.479

High

999765

ROK1
ATP-dependent RNA helicase rok1

1

2

High-throughput

0.479

High

999766

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

999772

HAS1
ATP-dependent RNA helicase has1

1

2

High-throughput

0.479

High

999773

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

999774

NEP1
Ribosomal RNA small subunit methyltransferase mra1

1

1

High-throughput

0.479

High

999775

RRP6
Exosome complex exonuclease rrp6

1

5

High-throughput

0.479

High

999776

RL18A
Large ribosomal subunit protein eL18A

1

1

High-throughput

0.479

High

999777

NDC80
Kinetochore protein ndc80

1

1

High-throughput

0.479

High

999779

RT05
Small ribosomal subunit protein uS5m

1

2

High-throughput

0.479

High

999780

SSB1
Ribosome-associated molecular chaperone sks2

1

3

High-throughput

0.479

High

999782

RL25A
Large ribosomal subunit protein uL23A

1

2

High-throughput

0.479

High

999784

IF4G
Eukaryotic translation initiation factor 4 gamma

1

2

High-throughput

0.479

High

999785

CDC28
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28

1

1

High-throughput

0.479

High

999787

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

999788

NOP9
Nucleolar protein 9

1

1

High-throughput

0.479

High

999795

BRX1
Ribosome biogenesis protein brx1

1

3

High-throughput

0.479

High

999801

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.479

High

999805

RS8B
Small ribosomal subunit protein eS8B

1

1

High-throughput

0.479

High

999806

YKU5
Uncharacterized WD repeat-containing protein C2E1P5.05

1

2

High-throughput

0.479

High

999808

FLP1
Tyrosine-protein phosphatase CDC14 homolog

1

1

High-throughput

0.479

High

999812

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

999816

BFR2
Protein bfr2

1

1

High-throughput

0.479

High

999821

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

999826

RS15B
Small ribosomal subunit protein uS19B

1

2

High-throughput

0.479

High

251515

SFC4
Transcription factor tau subunit sfc4

1

0

High-throughput

0.460

High

140811

TERT
Telomerase reverse transcriptase

1

0

High-throughput

0.458

High

141998

PRP46
Pre-mRNA-splicing factor prp5

1

0

High-throughput

0.458

High

142015

MRD1
Multiple RNA-binding domain-containing protein 1

1

0

High-throughput

0.458

High

142258

SFI1
Protein sfi1

1

0

High-throughput

0.458

High

142264

FAR11
Factor arrest protein 11

1

0

High-throughput

0.458

High

142278

RL8
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

144011

YEG5
Ankyrin and IPT/TIG repeat-containing protein C26H5.05

1

0

High-throughput

0.458

High

144052

CBF5
H/ACA ribonucleoprotein complex subunit cbf5

1

0

High-throughput

0.458

High

144223

PNO1
Pre-rRNA-processing protein pno1

1

0

High-throughput

0.458

High

144300

RPA49
DNA-directed RNA polymerase I subunit rpa49

1

0

High-throughput

0.458

High

144376

PSD3
Phosphatidylserine decarboxylase proenzyme 3

1

0

High-throughput

0.458

High

193702

YEK9
Uncharacterized protein C4F10.09c

1

0

High-throughput

0.458

High

194020

RL34A
Large ribosomal subunit protein eL34A

1

0

High-throughput

0.458

High

194960

PAT1
Deadenylation-dependent mRNA-decapping factor pdc2

1

0

High-throughput

0.458

High

194986

NRDE2
Protein NRDE2 homolog

1

0

High-throughput

0.458

High

223473

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.458

High

223794

RS24B
Small ribosomal subunit protein eS24B

1

0

High-throughput

0.458

High

223930

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

224169

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

224205

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.458

High

251170

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

251200

FKBP4
FK506-binding protein 39 kDa

1

0

High-throughput

0.458

High

251296

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

251408

YOCE
Uncharacterized RNA-binding protein C4F6.14

1

0

High-throughput

0.458

High

251413

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

251788

CFT1
Protein cft1

1

0

High-throughput

0.458

High

251941

GRN1
GTPase grn1

1

0

High-throughput

0.458

High

252029

YBJC
Zinc finger CCCH domain-containing protein C337.12

1

0

High-throughput

0.458

High

252208

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

252289

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

252564

MMI1
RNA binding exosome specificity factor Mmi1

1

0

High-throughput

0.458

High

292779

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

292807

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

292849

NOP2
25S rRNA

1

0

High-throughput

0.458

High

293047

PIR2
NURS complex subunit pir2

1

0

High-throughput

0.458

High

293275

REXO4
RNA exonuclease 4

1

0

High-throughput

0.458

High

293318

YQFB
Uncharacterized RNA-binding protein C126.11c

1

0

High-throughput

0.458

High

293597

ALP14
Spindle pole body component alp14

1

0

High-throughput

0.458

High

392004

H2A2
Histone H2A-beta

1

0

High-throughput

0.458

High

392627

H2B1
Histone H2B-alpha

1

0

High-throughput

0.458

High

404433

RL19A
Large ribosomal subunit protein eL19A

1

0

High-throughput

0.458

High

568527

RYH1
GTP-binding protein ryh1

1

0

High-throughput

0.458

High

624018

DBP2
ATP-dependent RNA helicase dbp2

1

0

High-throughput

0.458

High

724308

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

772820

RL3A
Large ribosomal subunit protein uL3A

1

0

High-throughput

0.458

High

784817

GAR2
Protein gar2

1

0

High-throughput

0.458

High

840111

SSP1
Serine/threonine-protein kinase ssp1

1

0

High-throughput

0.458

High

856635

RL30A
Large ribosomal subunit protein eL30A

1

0

High-throughput

0.458

High

945102

MID1
Anillin-related medial ring protein mid1

1

0

High-throughput

0.458

High

945115

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

High-throughput

0.458

High

945175

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

953590

HIR3
Histone transcription regulator 3 homolog

1

0

High-throughput

0.458

High

998267

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

999704

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

999763

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

999764

GEF1
Rho guanine nucleotide exchange factor gef1

1

0

High-throughput

0.458

High

999767

KRI1
Protein kri1

1

0

High-throughput

0.458

High

999769

EFG1P
rRNA-processing protein efg1

1

0

High-throughput

0.458

High

999781

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.458

High

999783

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

999786

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.458

High

999790

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

999794

TRA1
Transcription-associated protein 1

1

0

High-throughput

0.458

High

999796

RL43A
Large ribosomal subunit protein eL43A

1

0

High-throughput

0.458

High

999798

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

999803

AIR1
Protein air1

1

0

High-throughput

0.458

High

999804

YN84
Uncharacterized protein P35G2.04c

1

0

High-throughput

0.458

High

999807

ACON2
Aconitase-ribosomal protein bL21m fusion protein [Includes: Homocitrate dehydratase, mitochondrial

1

0

High-throughput

0.458

High

999809

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.458

High

999813

SIB1
Hydroxamate-type ferrichrome siderophore peptide synthetase

1

0

High-throughput

0.458

High

999815

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

999818

YHP4
Uncharacterized RNA-binding protein C902.04

1

0

High-throughput

0.458

High

999819

RL38A
Large ribosomal subunit protein eL38A

1

0

High-throughput

0.458

High

999820

ATH1
Ataxin-2 homolog

1

0

High-throughput

0.458

High

999822

RS26A
Small ribosomal subunit protein eS26A

1

0

High-throughput

0.458

High

999825

CID14
Poly(A) RNA polymerase cid14

1

0

High-throughput

0.458

High

999828

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.458

High

999829

PIF1
ATP-dependent DNA helicase pfh1

1

0

High-throughput

0.458

High

999830

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.458

High

999831

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.458

High

999834

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

224199

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

251388

RL25B
Large ribosomal subunit protein uL23B

1

2

High-throughput

0.437

High

293202

YG06
Uncharacterized protein C1604.06c

1

2

High-throughput

0.437

High

473838

RS27B
Ubiquitin-ribosomal protein eS31B fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31B

1

2

High-throughput

0.437

High

736872

RL28A
Large ribosomal subunit protein uL15A

1

1

High-throughput

0.437

High

945004

UTP18
Probable U3 small nucleolar RNA-associated protein 18

1

1

High-throughput

0.437

High

999770

RCL1
Probable RNA 3'-terminal phosphate cyclase-like protein

1

1

High-throughput

0.437

High

999791

YHU2
Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02

1

1

High-throughput

0.437

High

999797

UTP7
Probable U3 small nucleolar RNA-associated protein 7

1

3

High-throughput

0.437

High

999799

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.437

High

999817

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.437

High

87162

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

102126

TAM12
Uncharacterized protein tam12

1

0

High-throughput

0.249

Low

141972

RT28
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.249

Low

142482

YDYB
PH and SEC7 domain-containing protein C11E3.11c

1

0

High-throughput

0.249

Low

142721

NOP12
Nucleolar protein 12

1

0

High-throughput

0.249

Low

143960

RT04
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.249

Low

144940

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

144942

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.249

Low

145135

RAX2
Polarized growth protein rax2

1

0

High-throughput

0.249

Low

193688

LIPB
Probable octanoyltransferase

1

0

High-throughput

0.249

Low

223789

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

223887

RT35
Small ribosomal subunit protein mS45

1

0

High-throughput

0.249

Low

251381

YNV8
Uncharacterized protein C3H7.08c

1

0

High-throughput

0.249

Low

251491

SCW1
Cell wall integrity protein scw1

1

0

High-throughput

0.249

Low

251920

MU164
Microtubule-associated protein mug164

1

0

High-throughput

0.249

Low

293314

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

293487

MBO1
Gamma tubulin complex adapter mto1

1

0

High-throughput

0.249

Low

334002

ADH
Alcohol dehydrogenase

1

0

High-throughput

0.249

Low

453042

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.249

Low

612378

KIN1
Protein kinase kin1

1

0

High-throughput

0.249

Low

737040

ILVB
Acetolactate synthase, mitochondrial

1

0

High-throughput

0.249

Low

737043

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.249

Low

953465

DIMI
Mitosis protein dim1

1

0

High-throughput

0.249

Low

999759

RT24
Small ribosomal subunit protein mS35

1

0

High-throughput

0.249

Low

999761

MRP20
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

999762

CP51
Lanosterol 14-alpha demethylase erg11

1

0

High-throughput

0.249

Low

999768

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.249

Low

999771

ATCX
Phospholipid-transporting ATPase dnf2

1

0

High-throughput

0.249

Low

999789

RL24A
Large ribosomal subunit protein eL24A

1

0

High-throughput

0.249

Low

999792

YOM2
Uncharacterized protein PB7E8.02

1

0

High-throughput

0.249

Low

999793

YKP9
CRAL-TRIO domain-containing protein C589.09, mitochondrial

1

0

High-throughput

0.249

Low

999800

ATPD
ATP synthase subunit delta, mitochondrial

1

0

High-throughput

0.249

Low

999802

YNY5
LisH domain-containing protein C1711.05

1

0

High-throughput

0.249

Low

999810

NOP10
H/ACA ribonucleoprotein complex subunit nop10

1

0

High-throughput

0.249

Low

999814

RPA2
Probable DNA-directed RNA polymerase I subunit RPA2

1

0

High-throughput

0.249

Low

999823

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

999824

CO111
Rsm22-cox11 tandem protein 1, mitochondrial [Cleaved into: Ribosome assembly protein Rsm22-1; Cytochrome c oxidase assembly protein cox11-1]

1

0

High-throughput

0.249

Low

999832

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.249

Low

999833

MOK12
Cell wall alpha-1,3-glucan synthase mok12

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024