Protein: GRB2
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)

Gene: GRB2
Organism: Rattus norvegicus
Interactions: 13
UniProt ID: P62994

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005091 - guanyl-nucleotide exchange factor adaptor activity
GO:0005154 - epidermal growth factor receptor binding
GO:0005168 - neurotrophin TRKA receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924995

SHC1
SHC-transforming protein 1

4

20

Small-scale

0.873

High

724631

IRS1
Insulin receptor substrate 1

2

20

Small-scale

0.754

High

924998

Q9QX70
Receptor protein-tyrosine kinase

2

20

Small-scale

0.754

High

499159

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

2

20

Small-scale

0.714

High

728442

NTRK1
High affinity nerve growth factor receptor

1

20

Small-scale

0.708

High

599402

DYN1
Dynamin-1

1

20

Small-scale

0.665

High

94388

F1MAL5
Insulin receptor substrate 2

1

20

Small-scale

0.618

High

783504

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.618

High

924996

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

14

High-throughput

0.618

High

88774

D3ZV15
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

88884

D4A244
Fibroblast growth factor receptor substrate 2

1

20

Small-scale

0.479

High

924997

WIPF1
WAS/WASL-interacting protein family member 1

1

20

Small-scale

0.479

High

904380

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

20

Small-scale

0.445

High


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Last updated: 15 Jul 2024