Protein: LSM1
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)

Gene: LSM1
Organism: Homo sapiens
Interactions: 91
UniProt ID: O15116

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000339 - RNA cap binding
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000932 - P-body
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

167680

LSM3
U6 snRNA-associated Sm-like protein LSm3

7

20

High-throughput

0.971

High

167728

LSM4
U6 snRNA-associated Sm-like protein LSm4

6

20

Small-scale

0.940

High

167726

LSM2
U6 snRNA-associated Sm-like protein LSm2

5

20

High-throughput

0.925

High

167703

PATL1
Protein PAT1 homolog 1

5

10

Small-scale

0.923

High

167678

RUXF
Small nuclear ribonucleoprotein F

4

20

High-throughput

0.903

High

167681

LSM6
U6 snRNA-associated Sm-like protein LSm6

4

20

High-throughput

0.902

High

167727

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

20

High-throughput

0.811

High

167677

RUXE
Small nuclear ribonucleoprotein E

2

13

High-throughput

0.789

High

167725

LSM7
U6 snRNA-associated Sm-like protein LSm7

2

18

High-throughput

0.789

High

167690

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

15

High-throughput

0.754

High

167669

PSB8
Proteasome subunit beta type-8

3

2

High-throughput

0.661

High

167670

PSB5
Proteasome subunit beta type-5

3

2

High-throughput

0.661

High

124535

CLIC1
Chloride intracellular channel protein 1

4

0

Small-scale

0.661

High

167706

LS14A
Protein LSM14 homolog A

3

3

Small-scale

0.656

High

157690

GEMI2
Gem-associated protein 2

1

5

High-throughput

0.618

High

167659

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.618

High

167663

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

14

High-throughput

0.618

High

167672

ICLN
Methylosome subunit pICln

1

8

High-throughput

0.618

High

167679

RUXG
Small nuclear ribonucleoprotein G

1

19

High-throughput

0.618

High

167682

SMD1
Small nuclear ribonucleoprotein Sm D1

1

20

High-throughput

0.618

High

167683

SMD2
Small nuclear ribonucleoprotein Sm D2

1

20

High-throughput

0.618

High

167697

ZMYM1
Zinc finger MYM-type protein 1

2

0

High-throughput

0.585

High

167646

GSTA4
Glutathione S-transferase A4

2

0

High-throughput

0.580

High

167695

BEX5
Protein BEX5

2

0

High-throughput

0.580

High

87373

PATL2
Protein PAT1 homolog 2

1

9

Small-scale

0.575

High

167668

DDX6
Probable ATP-dependent RNA helicase DDX6

2

9

Small-scale

0.571

High

167653

TCL1B
T-cell leukemia/lymphoma protein 1B

2

2

High-throughput

0.553

High

167654

AGR2
Anterior gradient protein 2 homolog

2

2

High-throughput

0.553

High

167707

AGR3
Anterior gradient protein 3

2

2

High-throughput

0.553

High

167661

CLCA
Clathrin light chain A

1

3

High-throughput

0.536

High

167662

CLCB
Clathrin light chain B

1

3

High-throughput

0.536

High

167667

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

7

High-throughput

0.536

High

167671

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.513

High

167676

RAB14
Ras-related protein Rab-14

1

0

High-throughput

0.513

High

167688

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

167720

IL36B
Interleukin-36 beta

1

0

High-throughput

0.513

High

167721

PI4KB
Phosphatidylinositol 4-kinase beta

1

0

High-throughput

0.513

High

167647

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.508

High

167657

HS90A
Heat shock protein HSP 90-alpha

1

3

High-throughput

0.508

High

167689

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.508

High

167710

EXOS8
Exosome complex component RRP43

1

3

High-throughput

0.508

High

167723

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

1

High-throughput

0.508

High

167698

CI114
Putative methyltransferase C9orf114

1

0

High-throughput

0.493

High

120753

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.493

High

167666

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.493

High

167699

TM214
Transmembrane protein 214

1

0

High-throughput

0.486

High

167716

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.486

High

167722

UXT
Protein UXT

1

0

High-throughput

0.486

High

167655

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.481

High

167696

EXOS6
Exosome complex component MTR3

1

7

High-throughput

0.481

High

162199

XPO1
Exportin-1

1

4

High-throughput

0.479

High

167645

TIF1A
Transcription intermediary factor 1-alpha

1

2

Small-scale

0.479

High

167648

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.479

High

167651

PRP6
Pre-mRNA-processing factor 6

1

20

High-throughput

0.479

High

167652

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

167658

RU2B
U2 small nuclear ribonucleoprotein B''

1

17

High-throughput

0.479

High

167660

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.479

High

167664

EZRI
Ezrin

1

5

High-throughput

0.479

High

167665

HXK1
Hexokinase-1

1

1

High-throughput

0.479

High

167673

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

167674

GEMI4
Gem-associated protein 4

1

4

High-throughput

0.479

High

167685

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

4

High-throughput

0.479

High

167692

SMN
Survival motor neuron protein

1

8

High-throughput

0.479

High

167693

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

167694

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

5

High-throughput

0.479

High

167701

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

167702

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

167705

RHG18
Rho GTPase-activating protein 18

1

1

High-throughput

0.479

High

167708

GEMI6
Gem-associated protein 6

1

5

High-throughput

0.479

High

167709

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

167712

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

167714

DDX23
Probable ATP-dependent RNA helicase DDX23

1

11

High-throughput

0.479

High

167717

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

167718

GEMI8
Gem-associated protein 8

1

5

High-throughput

0.479

High

167724

DDX20
Probable ATP-dependent RNA helicase DDX20

1

16

High-throughput

0.479

High

167715

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

4

High-throughput

0.464

High

167649

N4BP1
NEDD4-binding protein 1

1

0

High-throughput

0.460

High

167687

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.460

High

167684

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

167691

ZFHX3
Zinc finger homeobox protein 3

1

0

High-throughput

0.458

High

167713

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.458

High

167719

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.458

High

3530

NBDY
Negative regulator of P-body association

1

1

Small-scale

0.445

High

167686

TAGL
Transgelin

1

1

High-throughput

0.445

High

167700

EDC4
Enhancer of mRNA-decapping protein 4

1

3

Small-scale

0.445

High

167704

XRN1
5'-3' exoribonuclease 1

1

3

Small-scale

0.445

High

167711

F136A
Protein FAM136A

1

0

High-throughput

0.438

High

49169

DAPL1
Death-associated protein-like 1

2

0

High-throughput

0.316

High

167675

MCCD1
Mitochondrial coiled-coil domain protein 1

2

0

High-throughput

0.316

High

167656

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.279

Low

167650

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024