Protein: ASNS
Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase)

Gene: ASNS
Organism: Homo sapiens
Interactions: 118
UniProt ID: P08243

Gene Ontology (top 5):
GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006529 - asparagine biosynthetic process
GO:0006541 - glutamine metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438959

TRI69
E3 ubiquitin-protein ligase TRIM69

4

1

High-throughput

0.698

High

438902

HSP7C
Heat shock cognate 71 kDa protein

4

2

High-throughput

0.678

High

226304

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

438973

OTUB1
Ubiquitin thioesterase OTUB1

2

1

High-throughput

0.571

High

438999

SHOC2
Leucine-rich repeat protein SHOC-2

2

1

High-throughput

0.571

High

438929

ATX1
Ataxin-1

1

3

High-throughput

0.541

High

438965

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

438967

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

2

High-throughput

0.536

High

438969

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.536

High

243817

BRD4
Bromodomain-containing protein 4

2

5

High-throughput

0.533

High

438906

CEBPB
CCAAT/enhancer-binding protein beta

2

2

Small-scale

0.533

High

57958

WDR27
WD repeat-containing protein 27

1

3

High-throughput

0.523

High

438909

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.521

High

380231

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

438904

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.513

High

438974

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

438981

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.513

High

438984

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

438989

PICK1
PRKCA-binding protein

1

0

High-throughput

0.513

High

439001

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

438990

STRN4
Striatin-4

1

3

High-throughput

0.494

High

438934

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.493

High

439000

RNF11
RING finger protein 11

1

2

High-throughput

0.489

High

243263

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.479

High

294281

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

322089

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

337801

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

345731

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

384124

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

434118

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

8

High-throughput

0.479

High

438901

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

438910

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

438912

FGFR4
Fibroblast growth factor receptor 4

1

8

High-throughput

0.479

High

438913

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

438914

TTP
mRNA decay activator protein ZFP36

1

1

High-throughput

0.479

High

438918

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

438919

HS71L
Heat shock 70 kDa protein 1-like

1

2

High-throughput

0.479

High

438922

VGFR3
Vascular endothelial growth factor receptor 3

1

4

High-throughput

0.479

High

438923

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

438924

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

438927

CDK9
Cyclin-dependent kinase 9

1

2

High-throughput

0.479

High

438933

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

438937

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

438938

EP300
Histone acetyltransferase p300

1

6

High-throughput

0.479

High

438941

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

438943

CUL3
Cullin-3

1

5

High-throughput

0.479

High

438951

NTRK3
NT-3 growth factor receptor

1

6

High-throughput

0.479

High

438955

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

438956

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

438968

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

438972

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.479

High

438977

NECD
Necdin

1

1

High-throughput

0.479

High

438978

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

438979

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

438983

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

438991

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.479

High

438994

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

438995

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

438997

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

1

High-throughput

0.479

High

438998

ALK
ALK tyrosine kinase receptor

1

5

High-throughput

0.479

High

119097

LEG9
Galectin-9

1

0

High-throughput

0.458

High

298070

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

438908

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

Small-scale

0.458

High

438916

T2EA
General transcription factor IIE subunit 1

1

0

Small-scale

0.458

High

438921

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.458

High

438928

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.458

High

438930

EPHA5
Ephrin type-A receptor 5

1

0

High-throughput

0.458

High

438931

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

438935

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

438942

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

438946

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

438949

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

438950

STXB2
Syntaxin-binding protein 2

1

0

High-throughput

0.458

High

438966

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

438970

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

438975

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

438993

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

438996

TES
Testin

1

0

High-throughput

0.458

High

438932

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.457

High

438954

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

438903

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

438905

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

438907

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

3

Small-scale

0.437

High

438915

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

438920

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

438936

TF2B
Transcription initiation factor IIB

1

4

Small-scale

0.437

High

438939

MMRN1
Multimerin-1

1

1

High-throughput

0.437

High

438940

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

438944

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.437

High

438952

DUS28
Dual specificity phosphatase 28

1

1

High-throughput

0.437

High

438957

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

438958

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

438960

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

5

Small-scale

0.437

High

438963

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.437

High

438986

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

438987

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

438988

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.437

High

438945

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

438948

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

401283

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

438964

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

438985

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.407

High

438926

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.373

High

438980

SH3G3
Endophilin-A3

2

0

High-throughput

0.298

High

237868

AP180
Clathrin coat assembly protein AP180

1

0

High-throughput

0.279

Low

438917

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

438982

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

438962

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.269

Low

302805

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

438911

TBP
TATA-box-binding protein

1

0

Small-scale

0.249

Low

438925

PERI
Peripherin

1

0

High-throughput

0.249

Low

438947

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

438953

FA78A
Protein FAM78A

1

0

High-throughput

0.249

Low

438961

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

438971

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

438976

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.249

Low

438992

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low

3531

NBDY
Negative regulator of P-body association

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024