Protein: NICA
Nicastrin

Gene: NICA, At3g52640/At3g52650
Organism: Arabidopsis thaliana
Interactions: 37
UniProt ID: Q8GUM5

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0016485 - protein processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1298958

PEN2
Probable gamma-secretase subunit PEN-2

1

3

Small-scale

0.647

High

264943

PSNA
Presenilin-like protein At1g08700

1

6

Small-scale

0.501

High

1298945

APH1
Gamma-secretase subunit APH1-like

1

6

Small-scale

0.501

High

945407

ACBP6
Acyl-CoA-binding domain-containing protein 6

1

1

High-throughput

0.481

High

1184901

TRXH5
Thioredoxin H5

1

4

High-throughput

0.481

High

1298947

PIP15
Probable aquaporin PIP1-5

1

3

High-throughput

0.481

High

1298948

NHL6
NDR1/HIN1-like protein 6

1

1

High-throughput

0.481

High

1298950

Q8RYE2
Camphor resistance CrcB family protein

1

1

High-throughput

0.481

High

1298951

DERL1
Derlin-1

1

2

High-throughput

0.481

High

1298957

DHAR1
Glutathione S-transferase DHAR1, mitochondrial

1

1

High-throughput

0.481

High

1298962

Q9LW08
signal peptidase I

1

3

High-throughput

0.481

High

1298964

MSBP2
Membrane steroid-binding protein 2

1

5

High-throughput

0.481

High

1298970

Q9SZP6
AT4g38690/F20M13_250

1

1

High-throughput

0.481

High

89383

PAM74
Probable LRR receptor-like serine/threonine-protein kinase PAM74

1

1

High-throughput

0.439

High

103174

F4K1J1
Calcineurin-like metallo-phosphoesterase superfamily protein

1

1

High-throughput

0.439

High

103605

F4K8C4
YGGT family protein

1

1

High-throughput

0.439

High

1231970

Q6E248
Membrane lipoprotein

1

1

High-throughput

0.439

High

1236658

ARGOS
Protein AUXIN-REGULATED GENE INVOLVED IN ORGAN SIZE

1

1

High-throughput

0.439

High

1283575

RUS3
Protein root UVB sensitive 3

1

1

High-throughput

0.439

High

1284388

HHP2
Heptahelical transmembrane protein 2

1

3

High-throughput

0.439

High

1298946

BETL2
Bet1-like protein At1g29060

1

1

High-throughput

0.439

High

1298949

Q8RY98
Serine/Threonine-kinase RLCKVII protein

1

1

High-throughput

0.439

High

1298952

Q94F23
Transmembrane protein

1

1

High-throughput

0.439

High

1298953

Q9AST5
ER membrane protein complex subunit 6

1

2

High-throughput

0.439

High

1298954

CNIH1
Protein cornichon homolog 1

1

1

High-throughput

0.439

High

1298955

CP21D
Peptidyl-prolyl cis-trans isomerase CYP21-4

1

1

High-throughput

0.439

High

1298956

KCS20
3-ketoacyl-CoA synthase 20

1

1

High-throughput

0.439

High

1298959

WAK3
Wall-associated receptor kinase 3

1

1

High-throughput

0.439

High

1298960

VP601
Vacuolar protein sorting-associated protein 60.1

1

1

High-throughput

0.439

High

1298961

UBC32
Ubiquitin-conjugating enzyme E2 32

1

3

High-throughput

0.439

High

1298963

Q9M0V8
At4g05370

1

1

High-throughput

0.439

High

1298965

GONS5
GDP-mannose transporter GONST5

1

1

High-throughput

0.439

High

1298966

UBC34
Ubiquitin-conjugating enzyme E2 34

1

3

High-throughput

0.439

High

1298967

SBP3
Probable steroid-binding protein 3

1

5

High-throughput

0.439

High

1298968

Q9SVG8
Leucine-rich repeat protein kinase family protein

1

1

High-throughput

0.439

High

1298969

HHP4
Heptahelical transmembrane protein 4

1

3

High-throughput

0.439

High

1298971

TRXH7
Thioredoxin H7

1

4

High-throughput

0.439

High


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Last updated: 11Aug2025