Protein: VAV2
Guanine nucleotide exchange factor VAV2 (VAV-2)

Gene: VAV2
Organism: Homo sapiens
Interactions: 90
UniProt ID: P52735

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001784 - phosphotyrosine residue binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005154 - epidermal growth factor receptor binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338167

EGFR
Epidermal growth factor receptor

7

20

Small-scale

0.951

High

855816

TITIN
Titin

2

5

High-throughput

0.801

High

855781

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.789

High

855783

3BP2
SH3 domain-binding protein 2

2

11

Small-scale

0.786

High

383705

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

601860

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

181827

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.754

High

796531

KSYK
Tyrosine-protein kinase SYK

2

20

Small-scale

0.744

High

441472

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

855792

GAB1
GRB2-associated-binding protein 1

1

17

High-throughput

0.692

High

855787

SHC2
SHC-transforming protein 2

1

20

High-throughput

0.691

High

855784

SRPK2
SRSF protein kinase 2

1

6

High-throughput

0.656

High

855803

CE170
Centrosomal protein of 170 kDa

1

14

High-throughput

0.656

High

855832

STK24
Serine/threonine-protein kinase 24

1

20

High-throughput

0.656

High

855797

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

855808

ABI1
Abl interactor 1

1

20

Small-scale

0.647

High

610308

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.641

High

412098

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.621

High

384538

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

452375

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.618

High

851378

NEK3
Serine/threonine-protein kinase Nek3

1

15

Small-scale

0.618

High

855778

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

855779

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

855782

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

855804

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

855823

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

855788

CAV1
Caveolin-1

1

2

Small-scale

0.604

High

855777

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.590

High

855789

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

Small-scale

0.575

High

855824

MARH7
E3 ubiquitin-protein ligase MARCHF7

2

0

Small-scale

0.575

High

272794

TM1L1
TOM1-like protein 1

1

2

High-throughput

0.573

High

548197

CD19
B-lymphocyte antigen CD19

1

3

Small-scale

0.561

High

855828

S12A6
Solute carrier family 12 member 6

1

1

Small-scale

0.561

High

855830

TRRAP
Transformation/transcription domain-associated protein

1

7

High-throughput

0.553

High

487256

ANDR
Androgen receptor

1

19

High-throughput

0.536

High

855821

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

4

Small-scale

0.536

High

855822

TXNIP
Thioredoxin-interacting protein

1

4

Small-scale

0.536

High

679335

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

6

High-throughput

0.536

High

855786

SMAD3
Mothers against decapentaplegic homolog 3

1

4

Small-scale

0.515

High

203351

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

4

High-throughput

0.508

High

273403

PPM1B
Protein phosphatase 1B

1

2

High-throughput

0.508

High

305158

UBE4B
Ubiquitin conjugation factor E4 B

1

1

High-throughput

0.508

High

610203

CCNO
Cyclin-O

1

2

High-throughput

0.508

High

826580

TCPG
T-complex protein 1 subunit gamma

1

6

High-throughput

0.508

High

839920

F10A1
Hsc70-interacting protein

1

6

High-throughput

0.508

High

854998

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

16

High-throughput

0.508

High

855776

RD23A
UV excision repair protein RAD23 homolog A

1

11

High-throughput

0.508

High

855785

TCPB
T-complex protein 1 subunit beta

1

6

High-throughput

0.508

High

855796

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

13

High-throughput

0.508

High

855798

TRBP2
RISC-loading complex subunit TARBP2

1

3

High-throughput

0.508

High

855802

DJC21
DnaJ homolog subfamily C member 21

1

5

High-throughput

0.508

High

855805

5MP2
eIF5-mimic protein 2

1

3

High-throughput

0.508

High

855807

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

13

High-throughput

0.508

High

855809

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

9

High-throughput

0.508

High

855810

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.508

High

855811

PNMA1
Paraneoplastic antigen Ma1

1

5

High-throughput

0.508

High

855813

IPO4
Importin-4

1

6

High-throughput

0.508

High

855814

PHF10
PHD finger protein 10

1

1

High-throughput

0.508

High

855818

HS105
Heat shock protein 105 kDa

1

9

High-throughput

0.508

High

855820

SRRT
Serrate RNA effector molecule homolog

1

3

High-throughput

0.508

High

855825

BIRC6
Baculoviral IAP repeat-containing protein 6

1

2

High-throughput

0.508

High

855829

CHMP3
Charged multivesicular body protein 3

1

3

High-throughput

0.508

High

855831

ARI1
E3 ubiquitin-protein ligase ARIH1

1

7

High-throughput

0.508

High

270188

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.486

High

375807

FUCO
Tissue alpha-L-fucosidase

1

0

High-throughput

0.486

High

826393

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.486

High

855806

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.486

High

855819

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.486

High

855791

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

Small-scale

0.481

High

239092

CTND1
Catenin delta-1

1

15

Small-scale

0.479

High

329523

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.479

High

503732

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

555104

CD44
CD44 antigen

1

1

Small-scale

0.479

High

560471

PRLR
Prolactin receptor

1

20

Small-scale

0.479

High

650740

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

855780

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

855795

CUL4A
Cullin-4A

1

9

High-throughput

0.479

High

855827

RTEL1
Regulator of telomere elongation helicase 1

1

1

High-throughput

0.479

High

146714

NCKP5
Nck-associated protein 5

1

7

High-throughput

0.464

High

855801

BRDT
Bromodomain testis-specific protein

1

7

High-throughput

0.464

High

855812

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

20

High-throughput

0.464

High

855817

DCNL4
DCN1-like protein 4

1

1

High-throughput

0.464

High

855800

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

90020

D6RA96
Regulator of telomere elongation helicase 1

1

1

High-throughput

0.445

High

855799

SF01
Splicing factor 1

1

9

High-throughput

0.417

High

855790

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.265

Low

855793

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.265

Low

855794

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.265

Low

855815

TCP11
T-complex protein 11 homolog

1

0

High-throughput

0.265

Low

855826

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024