Protein: BOP1
Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)

Gene: BOP1
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q14137

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

132144

PESC
Pescadillo homolog

9

3

Small-scale

0.972

High

1048903

WDR12
Ribosome biogenesis protein WDR12

6

20

Small-scale

0.943

High

1048907

WDR55
WD repeat-containing protein 55

2

20

High-throughput

0.811

High

171773

WDR46
WD repeat-containing protein 46

2

16

High-throughput

0.789

High

1048910

ANLN
Anillin

2

5

High-throughput

0.754

High

913524

RL7A
Large ribosomal subunit protein eL8

1

6

High-throughput

0.691

High

1048925

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.691

High

1048875

WDR48
WD repeat-containing protein 48

1

20

High-throughput

0.665

High

1048893

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.656

High

1048859

RL7L
Ribosomal protein uL30-like

3

6

Small-scale

0.656

High

916571

RS6
Small ribosomal subunit protein eS6

3

2

High-throughput

0.643

High

244422

BRD4
Bromodomain-containing protein 4

3

13

High-throughput

0.640

High

322607

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

12

High-throughput

0.640

High

346754

MYC
Myc proto-oncogene protein

3

14

High-throughput

0.640

High

271321

NPM3
Nucleoplasmin-3

2

4

High-throughput

0.628

High

418264

NPM
Nucleophosmin

2

4

High-throughput

0.628

High

182747

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.618

High

211179

BUB3
Mitotic checkpoint protein BUB3

1

19

Small-scale

0.618

High

903217

WDR5
WD repeat-containing protein 5

1

15

High-throughput

0.618

High

1048848

BOP1
Ribosome biogenesis protein BOP1

1

17

Small-scale

0.618

High

1048862

WDR74
WD repeat-containing protein 74

1

20

Small-scale

0.618

High

1048874

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1048886

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

19

High-throughput

0.618

High

1048908

RC3H2
Roquin-2

1

9

High-throughput

0.618

High

1048913

NLE1
Notchless protein homolog 1

1

18

High-throughput

0.618

High

1048916

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.618

High

1048923

FBW1A
F-box/WD repeat-containing protein 1A

1

18

High-throughput

0.618

High

1048854

IF16
Gamma-interferon-inducible protein 16

2

7

High-throughput

0.611

High

159713

CASQ2
Calsequestrin-2

3

9

High-throughput

0.609

High

1048890

PRR11
Proline-rich protein 11

2

0

High-throughput

0.602

High

69582

B0UZZ8
Chromosome 6 open reading frame 11

1

19

High-throughput

0.575

High

369581

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

148795

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.553

High

1048853

ACAP1
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

1

1

Small-scale

0.553

High

1048864

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

1048870

AHI1
Jouberin

1

20

Small-scale

0.553

High

1048906

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.553

High

1048918

FBW1B
F-box/WD repeat-containing protein 11

1

18

High-throughput

0.553

High

269727

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

12

High-throughput

0.536

High

400896

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.536

High

489037

H14
Histone H1.4

1

6

High-throughput

0.536

High

559405

H13
Histone H1.3

1

6

High-throughput

0.536

High

577945

RL17
Large ribosomal subunit protein uL22

1

2

High-throughput

0.536

High

585468

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

2

High-throughput

0.536

High

586742

CSK22
Casein kinase II subunit alpha'

1

8

High-throughput

0.536

High

596050

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

1

High-throughput

0.536

High

642345

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

736455

RL4
Large ribosomal subunit protein uL4

1

4

High-throughput

0.536

High

759655

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.536

High

773360

RL13A
Large ribosomal subunit protein uL13

1

3

High-throughput

0.536

High

781739

MNDA
Myeloid cell nuclear differentiation antigen

1

7

High-throughput

0.536

High

790396

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

842494

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.536

High

923008

RL11
Large ribosomal subunit protein uL5

1

3

High-throughput

0.536

High

934161

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.536

High

942647

SRPK2
SRSF protein kinase 2

1

12

High-throughput

0.536

High

1028652

SRSF5
Serine/arginine-rich splicing factor 5

1

9

High-throughput

0.536

High

1028906

SRSF6
Serine/arginine-rich splicing factor 6

1

12

High-throughput

0.536

High

1040551

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1041545

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1048868

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.536

High

1048881

RAD50
DNA repair protein RAD50

1

13

High-throughput

0.536

High

1048888

AURKB
Aurora kinase B

1

4

High-throughput

0.536

High

1048915

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.536

High

1048919

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

1048921

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

255763

OBSL1
Obscurin-like protein 1

2

4

High-throughput

0.533

High

531824

PDIA4
Protein disulfide-isomerase A4

1

10

High-throughput

0.515

High

685948

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.515

High

827201

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.515

High

168923

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.513

High

321771

WIZ
Protein Wiz

1

0

High-throughput

0.513

High

739712

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

1048887

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

180314

MAGB2
Melanoma-associated antigen B2

1

3

High-throughput

0.489

High

224938

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

364887

FRIL
Ferritin light chain

1

3

High-throughput

0.489

High

796569

KSYK
Tyrosine-protein kinase SYK

1

2

High-throughput

0.489

High

983608

FAK1
Focal adhesion kinase 1

1

6

High-throughput

0.489

High

1048866

PNM8A
Paraneoplastic antigen-like protein 8A

1

3

High-throughput

0.489

High

1048872

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

1048917

IL17B
Interleukin-17B

1

1

High-throughput

0.489

High

1048924

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.489

High

122747

MEN1
Menin

1

4

High-throughput

0.479

High

133480

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

179629

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

209974

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

258019

DNJB6
DnaJ homolog subfamily B member 6

1

7

High-throughput

0.479

High

308695

KI20A
Kinesin-like protein KIF20A

1

10

High-throughput

0.479

High

379391

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

386714

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

401985

JUN
Transcription factor Jun

1

9

High-throughput

0.479

High

442152

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

552696

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

603496

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.479

High

651172

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

720432

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

722408

RL22
Large ribosomal subunit protein eL22

1

2

High-throughput

0.479

High

724821

MYH9
Myosin-9

1

2

Small-scale

0.479

High

760053

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.479

High

779390

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

823992

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

8

High-throughput

0.479

High

890660

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.479

High

918352

H2B1C
Histone H2B type 1-C/E/F/G/I

1

7

High-throughput

0.479

High

922162

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

934751

H31
Histone H3.1

1

9

High-throughput

0.479

High

969686

KIF23
Kinesin-like protein KIF23

1

7

High-throughput

0.479

High

1048850

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

4

High-throughput

0.479

High

1048852

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1048855

DUS5
Dual specificity protein phosphatase 5

1

1

High-throughput

0.479

High

1048857

HABP4
Intracellular hyaluronan-binding protein 4

1

2

High-throughput

0.479

High

1048858

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1048860

IFIX
Pyrin and HIN domain-containing protein 1

1

7

High-throughput

0.479

High

1048861

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

4

Small-scale

0.479

High

1048867

ZCH18
Zinc finger CCCH domain-containing protein 18

1

13

High-throughput

0.479

High

1048871

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

High-throughput

0.479

High

1048873

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1048877

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1048878

NOC3L
Nucleolar complex protein 3 homolog

1

5

High-throughput

0.479

High

1048879

DNJC9
DnaJ homolog subfamily C member 9

1

9

High-throughput

0.479

High

1048880

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1048884

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

1048889

DDX27
Probable ATP-dependent RNA helicase DDX27

1

17

Small-scale

0.479

High

1048891

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1048892

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

8

Small-scale

0.479

High

1048895

RANB9
Ran-binding protein 9

1

7

High-throughput

0.479

High

1048896

RING2
E3 ubiquitin-protein ligase RING2

1

13

High-throughput

0.479

High

1048897

NECD
Necdin

1

3

High-throughput

0.479

High

1048898

MBB1A
Myb-binding protein 1A

1

2

Small-scale

0.479

High

1048899

MTG1
Mitochondrial ribosome-associated GTPase 1

1

9

High-throughput

0.479

High

1048901

DDX23
Probable ATP-dependent RNA helicase DDX23

1

7

High-throughput

0.479

High

1048904

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

1048909

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

High-throughput

0.479

High

1048911

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

1048912

MDN1
Midasin

1

13

Small-scale

0.479

High

1048922

NUDC
Nuclear migration protein nudC

1

8

High-throughput

0.479

High

1048926

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

3

High-throughput

0.470

High

1024861

KLF10
Krueppel-like factor 10

1

5

High-throughput

0.464

High

920182

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1048856

MIDN
Midnolin

1

0

High-throughput

0.458

High

1048914

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

920872

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

2

High-throughput

0.445

High

1048849

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

73125

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

1

High-throughput

0.437

High

164616

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

4

High-throughput

0.437

High

227419

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.437

High

255321

HIP1R
Huntingtin-interacting protein 1-related protein

1

5

Small-scale

0.437

High

298506

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.437

High

374215

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.437

High

384818

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

391692

H2A1B
Histone H2A type 1-B/E

1

6

High-throughput

0.437

High

981870

RON
Macrophage-stimulating protein receptor

1

3

High-throughput

0.437

High

1048851

CUL7
Cullin-7

1

2

High-throughput

0.437

High

1048863

SYT10
Synaptotagmin-10

1

1

Small-scale

0.437

High

1048865

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1048876

NEK9
Serine/threonine-protein kinase Nek9

1

3

High-throughput

0.437

High

1048882

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.437

High

1048885

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1048902

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1048920

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.437

High

56621

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.407

High

1048869

FMR1N
FMR1 neighbor protein

2

0

High-throughput

0.328

High

130242

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.279

Low

1048883

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

1048900

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

Small-scale

0.249

Low

1048905

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.249

Low

483686

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low

1048894

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024