Protein: RAD51
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)

Gene: RAD51
Organism: Homo sapiens
Interactions: 220
UniProt ID: Q06609

Gene Ontology (top 5):
GO:0000150 - DNA strand exchange activity
GO:0000152 - nuclear ubiquitin ligase complex
GO:0000228 - nuclear chromosome
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

847792

BRCA2
Breast cancer type 2 susceptibility protein

55

10

Small-scale

0.997

High

988062

RAD51
DNA repair protein RAD51 homolog 1

23

18

Small-scale

0.989

High

988075

DMC1
Meiotic recombination protein DMC1/LIM15 homolog

6

19

Small-scale

0.949

High

207041

XRCC3
DNA repair protein XRCC3

4

18

Small-scale

0.893

High

207144

XRCC2
DNA repair protein XRCC2

3

19

Small-scale

0.833

High

206275

RA51C
DNA repair protein RAD51 homolog 3

2

18

Small-scale

0.817

High

175492

RA51B
DNA repair protein RAD51 homolog 2

2

18

Small-scale

0.799

High

988100

PALB2
Partner and localizer of BRCA2

15

3

Small-scale

0.763

High

386591

P53
Cellular tumor antigen p53

11

3

Small-scale

0.761

High

802426

ATRX
Transcriptional regulator ATRX

11

18

Small-scale

0.759

High

795497

RAD52
DNA repair protein RAD52 homolog

11

6

Small-scale

0.758

High

749410

BRCA1
Breast cancer type 1 susceptibility protein

11

5

Small-scale

0.757

High

988113

R51A1
RAD51-associated protein 1

9

2

Small-scale

0.755

High

867575

BLM
RecQ-like DNA helicase BLM

9

14

Small-scale

0.754

High

988089

FIGL1
Fidgetin-like protein 1

4

6

Small-scale

0.704

High

988122

BARD1
BRCA1-associated RING domain protein 1

4

3

Small-scale

0.702

High

928075

SUMO1
Small ubiquitin-related modifier 1

4

2

Small-scale

0.694

High

651030

RFA1
Replication protein A 70 kDa DNA-binding subunit

4

3

Small-scale

0.687

High

930164

UBC9
SUMO-conjugating enzyme UBC9

4

5

Small-scale

0.681

High

337442

ABL1
Tyrosine-protein kinase ABL1

3

2

Small-scale

0.674

High

988170

RA54B
DNA repair and recombination protein RAD54B

3

16

Small-scale

0.667

High

295525

RECQ5
ATP-dependent DNA helicase Q5

3

14

Small-scale

0.660

High

552563

RFA2
Replication protein A 32 kDa subunit

3

5

Small-scale

0.653

High

548091

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

2

1

Small-scale

0.639

High

988074

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

2

14

Small-scale

0.634

High

988076

MDC1
Mediator of DNA damage checkpoint protein 1

2

2

Small-scale

0.634

High

988086

SWAP1
ATPase SWSAP1

2

4

Small-scale

0.634

High

658490

TEAD1
Transcriptional enhancer factor TEF-1

3

0

High-throughput

0.634

High

988107

FBH1
F-box DNA helicase 1

3

0

Small-scale

0.623

High

988103

FANCM
Fanconi anemia group M protein

1

6

Small-scale

0.618

High

988068

SQSTM
Sequestosome-1

3

0

Small-scale

0.613

High

154172

CHK1
Serine/threonine-protein kinase Chk1

2

1

Small-scale

0.612

High

614016

TBG1
Tubulin gamma-1 chain

2

5

Small-scale

0.611

High

988158

EVL
Ena/VASP-like protein

2

2

Small-scale

0.602

High

988097

SNX32
Sorting nexin-32

2

0

High-throughput

0.602

High

988140

RAD18
E3 ubiquitin-protein ligase RAD18

2

0

Small-scale

0.598

High

861712

PLK1
Serine/threonine-protein kinase PLK1

2

1

Small-scale

0.595

High

988106

MCPH1
Microcephalin

2

1

Small-scale

0.595

High

988126

FACD2
Fanconi anemia group D2 protein

2

1

Small-scale

0.595

High

988142

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

0

Small-scale

0.592

High

988088

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

1

Small-scale

0.586

High

275262

RNH2A
Ribonuclease H2 subunit A

2

0

Small-scale

0.585

High

988117

LRAT2
Protein LRATD2

1

1

High-throughput

0.582

High

988127

NSD3
Histone-lysine N-methyltransferase NSD3

1

3

High-throughput

0.582

High

893542

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.577

High

988073

SPIDR
DNA repair-scaffolding protein

1

0

Small-scale

0.571

High

988080

SWI5
DNA repair protein SWI5 homolog

2

0

Small-scale

0.569

High

988151

BCCIP
BRCA2 and CDKN1A-interacting protein

2

0

Small-scale

0.569

High

988162

AGO2
Protein argonaute-2

2

0

Small-scale

0.569

High

988139

TOPRS
E3 ubiquitin-protein ligase Topors

1

0

Small-scale

0.561

High

264147

DPOLQ
DNA polymerase theta

1

6

Small-scale

0.561

High

456113

DPOLA
DNA polymerase alpha catalytic subunit

1

1

Small-scale

0.561

High

622437

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.561

High

724536

IRS1
Insulin receptor substrate 1

1

2

Small-scale

0.561

High

830935

CTCF
Transcriptional repressor CTCF

1

1

Small-scale

0.561

High

978723

TF65
Transcription factor p65

1

1

Small-scale

0.561

High

988065

TP53B
TP53-binding protein 1

1

2

Small-scale

0.561

High

988084

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

6

Small-scale

0.561

High

988118

EP400
E1A-binding protein p400

1

1

Small-scale

0.561

High

988121

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

3

Small-scale

0.561

High

555426

H2AX
Histone H2AX

2

0

Small-scale

0.559

High

988154

MO4L1
Mortality factor 4-like protein 1

2

0

Small-scale

0.559

High

506496

ARY2
Arylamine N-acetyltransferase 2

1

0

High-throughput

0.558

High

431771

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.541

High

988078

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.541

High

988102

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

1

High-throughput

0.541

High

988155

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.541

High

988164

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

5

High-throughput

0.541

High

582245

NUCL
Nucleolin

1

0

Small-scale

0.537

High

659921

ERCC5
DNA excision repair protein ERCC-5

1

0

Small-scale

0.537

High

123244

CBX4
E3 SUMO-protein ligase CBX4

1

1

High-throughput

0.536

High

252992

HSF2B
Heat shock factor 2-binding protein

1

2

High-throughput

0.536

High

280971

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.536

High

551679

DESP
Desmoplakin

1

2

High-throughput

0.536

High

728472

MYH11
Myosin-11

1

1

High-throughput

0.536

High

846685

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

1

High-throughput

0.536

High

893929

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.536

High

970758

DSG1
Desmoglein-1

1

1

High-throughput

0.536

High

988090

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

1

High-throughput

0.536

High

988120

SPB12
Serpin B12

1

1

High-throughput

0.536

High

988124

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.536

High

988153

POLK
DNA polymerase kappa

1

1

High-throughput

0.536

High

988063

R51A2
RAD51-associated protein 2

1

0

Small-scale

0.529

High

988085

ARID2
AT-rich interactive domain-containing protein 2

1

0

Small-scale

0.529

High

988091

MMS22
Protein MMS22-like

1

0

Small-scale

0.529

High

162659

XPO1
Exportin-1

1

2

Small-scale

0.527

High

179982

MSH4
MutS protein homolog 4

1

3

Small-scale

0.527

High

238794

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.518

High

443473

VIME
Vimentin

1

0

High-throughput

0.518

High

505718

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.518

High

877562

CAD13
Cadherin-13

1

0

High-throughput

0.518

High

931603

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.518

High

988064

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.518

High

988110

NELFB
Negative elongation factor B

1

0

High-throughput

0.518

High

988168

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

2

High-throughput

0.515

High

988144

PARI
PCNA-interacting partner

1

0

Small-scale

0.513

High

270620

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

345075

CYTA
Cystatin-A

1

0

High-throughput

0.513

High

471579

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

503952

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

557540

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

0

High-throughput

0.513

High

559670

H12
Histone H1.2

1

0

High-throughput

0.513

High

759627

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

805524

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

0

Small-scale

0.513

High

914936

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

922135

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

933178

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.513

High

941648

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.513

High

964909

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.513

High

988082

KHDC1
KH homology domain-containing protein 1

1

0

High-throughput

0.513

High

988083

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

988087

CDC73
Parafibromin

1

0

High-throughput

0.513

High

988093

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.513

High

988109

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.513

High

988116

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.513

High

988119

HSFY1
Heat shock transcription factor, Y-linked

1

0

High-throughput

0.513

High

988137

HM20A
High mobility group protein 20A

1

0

High-throughput

0.513

High

988146

BABA2
BRISC and BRCA1-A complex member 2

1

0

Small-scale

0.513

High

988149

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.513

High

358748

CRYAA
Alpha-crystallin A chain

1

2

High-throughput

0.501

High

840459

VASP
Vasodilator-stimulated phosphoprotein

1

2

Small-scale

0.501

High

902544

SUMO2
Small ubiquitin-related modifier 2

1

2

Small-scale

0.501

High

988098

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

1

Small-scale

0.501

High

988104

ENAH
Protein enabled homolog

1

3

Small-scale

0.501

High

988108

WDR48
WD repeat-containing protein 48

1

2

Small-scale

0.501

High

988111

DDB2
DNA damage-binding protein 2

1

2

Small-scale

0.501

High

988125

MND1
Meiotic nuclear division protein 1 homolog

1

4

Small-scale

0.501

High

988143

FANCI
Fanconi anemia group I protein

1

2

Small-scale

0.501

High

377863

TFF1
Trefoil factor 1

1

1

High-throughput

0.494

High

988096

ITIH5
Inter-alpha-trypsin inhibitor heavy chain H5

1

2

High-throughput

0.494

High

988101

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.494

High

988169

ST14
Suppressor of tumorigenicity 14 protein

1

2

High-throughput

0.494

High

781684

EIF2D
Eukaryotic translation initiation factor 2D

1

0

High-throughput

0.493

High

988165

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.493

High

946502

DCD
Dermcidin

1

1

High-throughput

0.489

High

988163

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.489

High

430149

PROF1
Profilin-1

1

0

Small-scale

0.486

High

720297

RFA3
Replication protein A 14 kDa subunit

1

0

Small-scale

0.486

High

278061

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

Small-scale

0.481

High

988141

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

1

Small-scale

0.481

High

988166

ARIP4
Helicase ARIP4

1

14

Small-scale

0.481

High

246214

NBN
Nibrin

1

0

Small-scale

0.480

High

506574

BCR
Breakpoint cluster region protein

1

0

Small-scale

0.480

High

934123

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.480

High

959366

VIGLN
Vigilin

1

0

Small-scale

0.479

High

111482

J9JIF5
CXXC-type zinc finger protein 4

1

1

High-throughput

0.479

High

148712

CTRO
Citron Rho-interacting kinase

1

1

Small-scale

0.479

High

176588

FANCA
Fanconi anemia group A protein

1

2

Small-scale

0.479

High

294744

RECQ4
ATP-dependent DNA helicase Q4

1

14

Small-scale

0.479

High

360641

SPTA1
Spectrin alpha chain, erythrocytic 1

1

4

Small-scale

0.479

High

435066

SP1
Transcription factor Sp1

1

1

Small-scale

0.479

High

517212

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.479

High

532510

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.479

High

574145

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

3

Small-scale

0.479

High

598079

FLNA
Filamin-A

1

2

Small-scale

0.479

High

627242

MCM3
DNA replication licensing factor MCM3

1

1

Small-scale

0.479

High

658352

DPOD1
DNA polymerase delta catalytic subunit

1

1

Small-scale

0.479

High

668624

PML
Protein PML

1

2

Small-scale

0.479

High

707601

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.479

High

794239

MSH2
DNA mismatch repair protein Msh2

1

3

Small-scale

0.479

High

855460

MSH6
DNA mismatch repair protein Msh6

1

4

Small-scale

0.479

High

912276

SMD1
Small nuclear ribonucleoprotein Sm D1

1

1

Small-scale

0.479

High

912620

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

Small-scale

0.479

High

924506

GRB2
Growth factor receptor-bound protein 2

1

2

Small-scale

0.479

High

988072

KEAP1
Kelch-like ECH-associated protein 1

1

1

Small-scale

0.479

High

988094

DPOLN
DNA polymerase nu

1

1

Small-scale

0.479

High

988099

ZGRF1
5'-3' DNA helicase ZGRF1

1

1

Small-scale

0.479

High

988114

PF21A
PHD finger protein 21A

1

1

High-throughput

0.479

High

988115

Q96BE0
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

988133

BRD9
Bromodomain-containing protein 9

1

1

Small-scale

0.479

High

988138

TRI36
E3 ubiquitin-protein ligase TRIM36

1

2

Small-scale

0.479

High

988145

MCM9
DNA helicase MCM9

1

2

Small-scale

0.479

High

988150

RTEL1
Regulator of telomere elongation helicase 1

1

3

High-throughput

0.479

High

988152

HOP2
Homologous-pairing protein 2 homolog

1

2

Small-scale

0.479

High

988159

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

Small-scale

0.479

High

988160

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

988167

RN115
E3 ubiquitin-protein ligase RNF115

1

1

Small-scale

0.479

High

988070

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

Small-scale

0.460

High

988161

C8AP2
CASP8-associated protein 2

1

0

Small-scale

0.460

High

988171

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

0

Small-scale

0.460

High

232118

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

262256

ULK1
Serine/threonine-protein kinase ULK1

1

0

Small-scale

0.458

High

351359

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

369469

ESR1
Estrogen receptor

1

0

Small-scale

0.458

High

538917

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

Small-scale

0.458

High

569639

CEBPB
CCAAT/enhancer-binding protein beta

1

0

Small-scale

0.458

High

575399

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

881151

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.458

High

885510

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.458

High

890626

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

988067

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.458

High

988069

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

988077

PSF1
DNA replication complex GINS protein PSF1

1

0

Small-scale

0.458

High

988092

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

988123

SOSB1
SOSS complex subunit B1

1

0

Small-scale

0.458

High

988128

AICDA
Single-stranded DNA cytosine deaminase

1

0

Small-scale

0.458

High

988129

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

988131

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

Small-scale

0.458

High

988132

DUS21
Dual specificity protein phosphatase 21

1

0

High-throughput

0.458

High

988135

Q9HAV2
Heat shock transcription factor 1

1

0

High-throughput

0.458

High

988136

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

988147

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

Small-scale

0.458

High

891714

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.457

High

988112

RAD54
DNA repair and recombination protein RAD54-like

1

16

Small-scale

0.457

High

90021

D6RA96
Regulator of telomere elongation helicase 1

1

3

High-throughput

0.445

High

988130

CXXC4
CXXC-type zinc finger protein 4

1

1

High-throughput

0.445

High

988134

RMI1
RecQ-mediated genome instability protein 1

1

1

Small-scale

0.445

High

988148

DONS
Protein downstream neighbor of Son

1

0

Small-scale

0.426

High

988105

GG6L2
Golgin subfamily A member 6-like protein 2

1

4

High-throughput

0.407

High

988066

IL24
Interleukin-24

1

0

High-throughput

0.304

High

988079

CYTM
Cystatin-M

1

0

High-throughput

0.282

High

988157

PCS1N
ProSAAS

1

0

High-throughput

0.282

High

126800

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

428679

TRY1
Serine protease 1

1

0

High-throughput

0.279

Low

844495

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.279

Low

988071

LRP8
Low-density lipoprotein receptor-related protein 8

1

0

High-throughput

0.279

Low

988081

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.279

Low

988156

HMGX4
HMG domain-containing protein 4

1

0

High-throughput

0.279

Low

988095

RN180
E3 ubiquitin-protein ligase RNF180

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024