Protein: T2EA
General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)

Gene: T2EA, GTF2E1
Organism: Homo sapiens
Interactions: 69
UniProt ID: P29083

Gene Ontology (top 5):
GO:0001113 - transcription open complex formation at RNA polymerase II promoter
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0005673 - transcription factor TFIIE complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663996

T2EB
Transcription initiation factor IIE subunit beta

11

6

Small-scale

0.981

High

663998

TF2H1
General transcription factor IIH subunit 1

5

2

Small-scale

0.933

High

624779

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

1

Small-scale

0.806

High

664011

TF2B
Transcription initiation factor IIB

2

1

Small-scale

0.806

High

663999

T2FA
General transcription factor IIF subunit 1

4

1

Small-scale

0.694

High

664004

CDK7
Cyclin-dependent kinase 7

4

1

Small-scale

0.686

High

589788

TBP
TATA-box-binding protein

3

0

Small-scale

0.639

High

664040

NEMO
NF-kappa-B essential modulator

2

0

High-throughput

0.606

High

534066

T2FB
General transcription factor IIF subunit 2

2

1

Small-scale

0.602

High

584552

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

2

2

Small-scale

0.602

High

664008

H31
Histone H3.1

2

1

High-throughput

0.584

High

664003

TAF6
Transcription initiation factor TFIID subunit 6

2

0

Small-scale

0.577

High

612960

TCEA1
Transcription elongation factor A protein 1

2

0

Small-scale

0.560

High

664029

TF2H4
General transcription factor IIH subunit 4

1

1

Small-scale

0.550

High

664009

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.545

High

664030

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

2

High-throughput

0.541

High

158404

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

High-throughput

0.536

High

167479

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

1

High-throughput

0.536

High

664020

TAF11
Transcription initiation factor TFIID subunit 11

1

0

Small-scale

0.527

High

203441

MTG8R
Protein CBFA2T2

1

0

High-throughput

0.518

High

664028

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

0

High-throughput

0.518

High

664032

TRI15
E3 ubiquitin-protein ligase TRIM15

1

0

High-throughput

0.518

High

664034

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.518

High

664015

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

Small-scale

0.513

High

664035

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

170265

TIF1A
Transcription intermediary factor 1-alpha

1

1

Small-scale

0.501

High

174643

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

574128

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

1

Small-scale

0.501

High

664016

TF2H2
General transcription factor IIH subunit 2

1

1

Small-scale

0.501

High

664017

TF2H3
General transcription factor IIH subunit 3

1

1

Small-scale

0.501

High

394167

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

600087

TAF1
Transcription initiation factor TFIID subunit 1

1

0

Small-scale

0.480

High

664005

TF2AA
Transcription initiation factor IIA subunit 1

1

0

Small-scale

0.480

High

664013

TLE5
TLE family member 5

1

0

Small-scale

0.480

High

664023

TF2H5
General transcription factor IIH subunit 5

1

0

Small-scale

0.480

High

664024

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

Small-scale

0.480

High

239307

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.479

High

663997

PML
Protein PML

1

2

High-throughput

0.479

High

664002

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

664010

H33
Histone H3.3

1

1

High-throughput

0.479

High

664031

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.479

High

179557

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

243981

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

309284

KIF4A
Chromosome-associated kinesin KIF4A

1

0

High-throughput

0.458

High

359682

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

438916

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

Small-scale

0.458

High

455121

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

523539

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

632198

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

664001

COIL
Coilin

1

0

High-throughput

0.458

High

664007

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

664012

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

664014

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

664019

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

664021

MCAF1
Activating transcription factor 7-interacting protein 1

1

0

Small-scale

0.458

High

664026

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

664033

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

664036

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

664037

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

664039

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

664038

S45A2
Membrane-associated transporter protein

1

1

High-throughput

0.437

High

664000

BRCA1
Breast cancer type 1 susceptibility protein

1

0

Small-scale

0.426

High

90140

D6RGY6
Solute carrier family 45 member 2

1

1

High-throughput

0.407

High

664025

NRARP
Notch-regulated ankyrin repeat-containing protein

2

0

High-throughput

0.316

High

664027

TBC21
TBC1 domain family member 21

2

0

High-throughput

0.316

High

664018

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.282

High

664006

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

532061

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.269

Low

664022

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024