Protein: GBB
Guanine nucleotide-binding protein subunit beta

Gene: GBB, STE4
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P18851

Gene Ontology (top 5):
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation
GO:0001965 - G-protein alpha-subunit binding
GO:0005737 - cytoplasm
GO:0005834 - heterotrimeric G-protein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

440230

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

20

20

Small-scale

0.989

High

579396

GBG
Guanine nucleotide-binding protein subunit gamma

12

0

Small-scale

0.927

High

509396

CDC24
Cell division control protein 24

6

7

Small-scale

0.733

High

579444

PLP1
Phosducin-like protein 1

1

15

Small-scale

0.724

High

579410

STE5
Protein STE5

10

0

Small-scale

0.723

High

579398

FAR1
Cyclin-dependent kinase inhibitor FAR1

3

0

Small-scale

0.651

High

579443

STE20
Serine/threonine-protein kinase STE20

2

9

Small-scale

0.634

High

579420

AKR1
Palmitoyltransferase AKR1

4

4

Small-scale

0.632

High

579406

ARP2
Actin-related protein 2

1

8

High-throughput

0.618

High

579395

GBB
Guanine nucleotide-binding protein subunit beta

1

16

Small-scale

0.618

High

579438

CLA4
Serine/threonine-protein kinase CLA4

1

7

Small-scale

0.618

High

579435

MTR4
ATP-dependent RNA helicase DOB1

1

18

High-throughput

0.595

High

555793

VATB
V-type proton ATPase subunit B

2

7

High-throughput

0.584

High

579404

MAS5
Mitochondrial protein import protein MAS5

2

12

High-throughput

0.584

High

579441

ACT
Actin

1

7

High-throughput

0.578

High

579425

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

Small-scale

0.561

High

579445

PLP2
Phosducin-like protein 2

1

14

Small-scale

0.561

High

90173

STE2
Pheromone alpha factor receptor

2

0

Small-scale

0.559

High

579402

STE50
Protein STE50

2

0

Small-scale

0.559

High

579400

KC11
Casein kinase I homolog 1

1

13

Small-scale

0.552

High

579429

SSB2
Ribosome-associated molecular chaperone SSB2

2

17

High-throughput

0.552

High

519891

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.536

High

579417

YHJ3
Uncharacterized protein YHR033W

1

3

High-throughput

0.536

High

579421

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.536

High

579446

AHA1
Hsp90 co-chaperone AHA1

1

1

High-throughput

0.536

High

579413

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.513

High

579416

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.513

High

334885

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

7

High-throughput

0.500

High

342652

ENO1
Enolase 1

1

4

High-throughput

0.500

High

365756

HSP82
ATP-dependent molecular chaperone HSP82

1

10

High-throughput

0.500

High

367715

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.500

High

381419

GAL1
Galactokinase

1

3

High-throughput

0.500

High

449898

HSP73
Heat shock protein SSA3

1

16

High-throughput

0.500

High

485635

IF4A
ATP-dependent RNA helicase eIF4A

1

12

High-throughput

0.500

High

498429

METK1
S-adenosylmethionine synthase 1

1

3

High-throughput

0.500

High

510196

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.500

High

520907

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.500

High

543152

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.500

High

554545

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

579401

SCJ1
DnaJ-related protein SCJ1

1

10

High-throughput

0.500

High

579414

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.500

High

579418

YHI0
Putative proline--tRNA ligase YHR020W

1

4

High-throughput

0.500

High

579419

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.500

High

579426

SAHH
Adenosylhomocysteinase

1

2

High-throughput

0.500

High

579432

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.500

High

579434

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.500

High

579436

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.500

High

426361

PMM
Phosphomannomutase

1

1

High-throughput

0.489

High

579407

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

11

High-throughput

0.489

High

579422

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.489

High

579424

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

579430

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.489

High

579431

SYG1
Protein SYG1

1

0

Small-scale

0.486

High

579399

KIN3
Serine/threonine-protein kinase KIN3

1

7

High-throughput

0.481

High

579439

AF9
Protein AF-9 homolog

1

6

High-throughput

0.481

High

404298

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.479

High

410897

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

516961

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.479

High

419670

RHO1
GTP-binding protein RHO1

1

15

Small-scale

0.479

High

579440

APJ1
J domain-containing protein APJ1

1

13

High-throughput

0.479

High

579408

SSO1
Protein SSO1

1

0

High-throughput

0.460

High

579428

DSE1
Protein DSE1

1

0

Small-scale

0.458

High

579437

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

562674

FUS3
Mitogen-activated protein kinase FUS3

1

8

Small-scale

0.457

High

342342

CISY1
Citrate synthase, mitochondrial

1

1

High-throughput

0.457

High

378276

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

381680

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

2

High-throughput

0.457

High

540021

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

3

High-throughput

0.457

High

579397

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.457

High

579423

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.457

High

579433

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

579442

PRS8
26S proteasome regulatory subunit 8 homolog

1

10

High-throughput

0.457

High

424332

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.445

High

477876

HSP77
Import motor subunit, mitochondrial

1

19

High-throughput

0.445

High

490274

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

493148

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

579411

PRS7
26S proteasome regulatory subunit 7 homolog

1

12

High-throughput

0.445

High

579412

NUF2
Kinetochore protein NUF2

1

7

High-throughput

0.439

High

579405

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

579409

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

579427

RPN3
26S proteasome regulatory subunit RPN3

1

2

High-throughput

0.407

High

579403

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.279

Low

579415

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024