Protein: ELP3
Elongator complex protein 3 (hELP3) (EC 2.3.1.311) (tRNA uridine(34) acetyltransferase)

Gene: ELP3
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q9H9T3

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0001764 - neuron migration
GO:0002098 - tRNA wobble uridine modification
GO:0002926 - tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

305819

ELP1
Elongator complex protein 1

9

4

Small-scale

0.974

High

1151894

ELP2
Elongator complex protein 2

3

3

Small-scale

0.861

High

283031

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

1

High-throughput

0.754

High

1289388

ELP4
Elongator complex protein 4

4

1

Small-scale

0.683

High

893480

PRPS1
Ribose-phosphate pyrophosphokinase 1

3

1

High-throughput

0.667

High

666423

3MG
DNA-3-methyladenine glycosylase

3

0

High-throughput

0.638

High

1039173

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

2

High-throughput

0.628

High

1289835

KTI12
Protein KTI12 homolog

2

1

Small-scale

0.621

High

1012067

ELP6
Elongator complex protein 6

2

1

Small-scale

0.619

High

1283770

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.602

High

1281398

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.586

High

526685

GILT
Gamma-interferon-inducible lysosomal thiol reductase

2

0

High-throughput

0.585

High

1307345

DUS9
Dual specificity protein phosphatase 9

2

0

High-throughput

0.585

High

228738

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

1255785

ELP5
Elongator complex protein 5

2

0

Small-scale

0.576

High

1302986

MMS19
MMS19 nucleotide excision repair protein homolog

2

0

Small-scale

0.559

High

504779

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.547

High

515947

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

822381

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.536

High

1038926

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

2

High-throughput

0.536

High

1189519

ZFY16
Zinc finger FYVE domain-containing protein 16

1

1

High-throughput

0.536

High

1302132

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.536

High

1334475

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

1

High-throughput

0.536

High

1334480

TRAK1
Trafficking kinesin-binding protein 1

1

1

High-throughput

0.536

High

1334481

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.536

High

1255955

DCA11
DDB1- and CUL4-associated factor 11

1

0

High-throughput

0.517

High

780127

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

136070

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

243618

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

319058

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

331178

DNAL4
Dynein axonemal light chain 4

1

0

High-throughput

0.513

High

365067

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

781231

ETV3
ETS translocation variant 3

1

0

High-throughput

0.513

High

796178

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

858669

PPP5
Serine/threonine-protein phosphatase 5

1

0

High-throughput

0.513

High

986852

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1069515

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1297323

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1299166

IP6K3
Inositol hexakisphosphate kinase 3

1

0

High-throughput

0.513

High

1317408

NEUL
Neurolysin, mitochondrial

1

0

High-throughput

0.513

High

1318367

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.513

High

1334473

PAR6A
Partitioning defective 6 homolog alpha

1

0

High-throughput

0.513

High

1334474

ANLN
Anillin

1

0

High-throughput

0.513

High

1174661

H32
Histone H3.2

1

2

Small-scale

0.501

High

1334479

AT7L1
Ataxin-7-like protein 1

1

1

High-throughput

0.489

High

917949

H4
Histone H4

1

0

Small-scale

0.480

High

1334484

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

295270

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

567276

CXA1
Gap junction alpha-1 protein

1

1

Small-scale

0.479

High

999102

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1203512

SKAP1
Src kinase-associated phosphoprotein 1

1

1

High-throughput

0.479

High

1311544

PCGF1
Polycomb group RING finger protein 1

1

1

High-throughput

0.479

High

1316703

PCGF6
Polycomb group RING finger protein 6

1

1

High-throughput

0.479

High

1334476

MTMR4
Myotubularin-related protein 4

1

1

High-throughput

0.479

High

1334483

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

149303

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

340530

PGK1
Phosphoglycerate kinase 1

1

0

Small-scale

0.458

High

347925

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

517472

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

547221

EZRI
Ezrin

1

0

High-throughput

0.458

High

553747

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

639807

IKBA
NF-kappa-B inhibitor alpha

1

0

High-throughput

0.458

High

652286

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

909142

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

967976

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1042571

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1064731

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1085351

FSCN1
Fascin

1

0

High-throughput

0.458

High

1085685

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1148791

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1171763

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1215880

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1270451

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1331322

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1332622

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1334418

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1334477

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1334478

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1334482

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

56740

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

625048

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.426

High

1334472

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1086961

QPCT
Glutaminyl-peptide cyclotransferase

3

0

High-throughput

0.347

High

1140461

F219B
Protein FAM219B

3

0

High-throughput

0.347

High

1334485

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

225053

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.328

High

179264

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

1115348

PKHN1
Pleckstrin homology domain-containing family N member 1

1

0

High-throughput

0.279

Low

1293857

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

385541

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

721478

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1284644

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024