Protein: LRRF1
Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (GC-binding factor 2) (TAR RNA-interacting protein)

Gene: LRRF1, LRRFIP1
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q32MZ4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1023171

FLII
Protein flightless-1 homolog

7

2

Small-scale

0.751

High

657503

TMOD1
Tropomodulin-1

4

6

High-throughput

0.694

High

1103953

IFT74
Intraflagellar transport protein 74 homolog

2

4

High-throughput

0.628

High

1103967

TMOD3
Tropomodulin-3

2

6

High-throughput

0.628

High

1103968

TMOD4
Tropomodulin-4

2

6

High-throughput

0.628

High

1103972

TFR2
Transferrin receptor protein 2

2

1

High-throughput

0.611

High

538557

CCNB1
G2/mitotic-specific cyclin-B1

2

0

High-throughput

0.602

High

1103955

GA2L1
GAS2-like protein 1

2

0

High-throughput

0.602

High

1103962

TCAL2
Transcription elongation factor A protein-like 2

2

0

High-throughput

0.602

High

1103970

MCTS1
Malignant T-cell-amplified sequence 1

2

0

High-throughput

0.602

High

1103963

SH22A
SH2 domain-containing protein 2A

2

1

High-throughput

0.594

High

497125

TAU
Microtubule-associated protein tau

2

2

High-throughput

0.552

High

1103960

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.549

High

1103964

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.549

High

580653

ML12A
Myosin regulatory light chain 12A

1

2

High-throughput

0.536

High

809321

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

862047

DAPK1
Death-associated protein kinase 1

1

2

High-throughput

0.536

High

891807

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.536

High

929885

ACTG
Actin, cytoplasmic 2

1

5

High-throughput

0.536

High

1084957

DREB
Drebrin

1

1

High-throughput

0.536

High

1103944

CENPQ
Centromere protein Q

1

1

High-throughput

0.536

High

1103947

ABRA
Actin-binding Rho-activating protein

1

1

High-throughput

0.536

High

1103952

VMP1
Vacuole membrane protein 1

1

1

High-throughput

0.536

High

1103971

HECD1
E3 ubiquitin-protein ligase HECTD1

2

1

High-throughput

0.533

High

1037550

OLIG2
Oligodendrocyte transcription factor 2

1

0

High-throughput

0.518

High

932190

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.515

High

1061127

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.515

High

571726

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.513

High

1103973

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

791610

HD
Huntingtin

1

0

High-throughput

0.493

High

1103956

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.480

High

1103975

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

205459

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

301847

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

322706

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

352631

TNFA
Tumor necrosis factor

1

1

Small-scale

0.479

High

374316

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

504169

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

813510

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

884502

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.479

High

914100

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

918400

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

959451

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1049056

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1051297

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1063828

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

1085748

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1103950

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1103954

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

1103957

MYD88
Myeloid differentiation primary response protein MyD88

1

3

Small-scale

0.479

High

1103959

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

1103965

ANLN
Anillin

1

1

High-throughput

0.479

High

1103969

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

738764

SPB5
Serpin B5

1

0

Small-scale

0.460

High

233485

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

262468

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

384937

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

403245

LA
Lupus La protein

1

0

High-throughput

0.458

High

521972

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

641811

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

749554

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

870819

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

896116

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

981881

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.458

High

1016193

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1064363

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1103942

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1103943

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1103945

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1103946

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1103949

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1103951

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

1103958

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.458

High

1103961

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1103966

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

369723

ESR1
Estrogen receptor

1

2

High-throughput

0.445

High

717886

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

1032441

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

1103940

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.445

High

1103948

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

91498

E7ET36
Transferrin receptor 2

1

1

High-throughput

0.407

High

100819

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1103941

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1103974

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024