Protein: D3ZVH5
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27)

Gene: D3ZVH5, Mdm2
Organism: Rattus norvegicus
Interactions: 16
UniProt ID: D3ZVH5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001568 - blood vessel development
GO:0001974 - blood vessel remodeling
GO:0002027 - regulation of heart rate
GO:0002039 - p53 binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

93110

P53
Cellular tumor antigen p53

9

10

Small-scale

0.749

High

93121

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

4

Small-scale

0.618

High

93115

PPARA
Peroxisome proliferator-activated receptor alpha

1

8

Small-scale

0.573

High

93112

DLG4
Disks large homolog 4

1

3

Small-scale

0.561

High

93120

UT2
Urea transporter 2

1

1

Small-scale

0.489

High

93107

FOXO1
Forkhead box protein O1

1

4

Small-scale

0.479

High

93108

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.479

High

93109

GCR
Glucocorticoid receptor

1

6

Small-scale

0.479

High

93111

ARRB1
Beta-arrestin-1

1

4

Small-scale

0.479

High

93114

IRS1
Insulin receptor substrate 1

1

2

Small-scale

0.479

High

93116

CCNG1
Cyclin-G1

1

2

Small-scale

0.479

High

93117

B2CL1
Bcl-2-like protein 1

1

1

Small-scale

0.479

High

93118

RASF6
Ras association domain-containing protein 6

1

6

Small-scale

0.479

High

93119

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.479

High

93122

Q8VBU7
Beta-2 adrenergic receptor

1

1

Small-scale

0.479

High

93113

PGH2
Prostaglandin G/H synthase 2

1

0

Small-scale

0.458

High


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Last updated: 11Aug2025