Protein: AMRP
Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)

Gene: AMRP, LRPAP1
Organism: Homo sapiens
Interactions: 155
UniProt ID: P30533

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0002091 - negative regulation of receptor internalization
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674650

VLDLR
Very low-density lipoprotein receptor

6

10

Small-scale

0.954

High

674653

LRP1
Prolow-density lipoprotein receptor-related protein 1

6

10

Small-scale

0.951

High

674705

SORL
Sortilin-related receptor

6

11

Small-scale

0.949

High

674662

LRP8
Low-density lipoprotein receptor-related protein 8

6

10

Small-scale

0.947

High

674651

LRP2
Low-density lipoprotein receptor-related protein 2

5

10

Small-scale

0.928

High

351054

LDLR
Low-density lipoprotein receptor

4

10

Small-scale

0.906

High

254247

LRP4
Low-density lipoprotein receptor-related protein 4

2

10

High-throughput

0.811

High

674731

LRP1B
Low-density lipoprotein receptor-related protein 1B

2

10

High-throughput

0.811

High

674713

SORT
Sortilin

5

1

Small-scale

0.710

High

254449

ROCK2
Rho-associated protein kinase 2

2

0

High-throughput

0.602

High

674654

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.580

High

674678

SYDE2
Rho GTPase-activating protein SYDE2

2

1

High-throughput

0.571

High

674733

GMIP
GEM-interacting protein

2

0

High-throughput

0.547

High

674639

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.541

High

546592

ARSA
Arylsulfatase A

1

1

High-throughput

0.536

High

654103

CALX
Calnexin

1

1

High-throughput

0.536

High

674720

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.536

High

674709

CALR3
Calreticulin-3

2

1

High-throughput

0.533

High

674723

RTN4
Reticulon-4

1

0

High-throughput

0.518

High

674737

RPGFL
Rap guanine nucleotide exchange factor-like 1

1

1

High-throughput

0.515

High

130289

BT3A1
Butyrophilin subfamily 3 member A1

1

0

High-throughput

0.513

High

353266

CD4
T-cell surface glycoprotein CD4

1

0

High-throughput

0.513

High

655167

IL1R2
Interleukin-1 receptor type 2

1

0

High-throughput

0.513

High

674641

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.513

High

674712

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.513

High

674721

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

116974

SGK1
Serine/threonine-protein kinase Sgk1

1

0

High-throughput

0.493

High

637219

CATS
Cathepsin S

1

0

High-throughput

0.493

High

648658

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

674668

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.493

High

394187

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

606862

IDS
Iduronate 2-sulfatase

1

1

High-throughput

0.489

High

617249

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.489

High

674656

GNDS
Ral guanine nucleotide dissociation stimulator

1

1

Small-scale

0.481

High

204619

E41L2
Band 4.1-like protein 2

1

1

High-throughput

0.479

High

431180

CATB
Cathepsin B

1

1

High-throughput

0.479

High

531741

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.479

High

607893

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.479

High

674346

UFO
Tyrosine-protein kinase receptor UFO

1

1

High-throughput

0.479

High

674631

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

1

High-throughput

0.479

High

674632

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.479

High

674633

KC1E
Casein kinase I isoform epsilon

1

1

High-throughput

0.479

High

674657

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.479

High

674669

PDIA6
Protein disulfide-isomerase A6

1

2

High-throughput

0.479

High

674676

EPHAA
Ephrin type-A receptor 10

1

1

High-throughput

0.479

High

674693

DJC10
DnaJ homolog subfamily C member 10

1

4

High-throughput

0.479

High

674700

DJB14
DnaJ homolog subfamily B member 14

1

4

High-throughput

0.479

High

674701

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

1

High-throughput

0.479

High

674728

DJB12
DnaJ homolog subfamily B member 12

1

4

High-throughput

0.479

High

674734

DNJB9
DnaJ homolog subfamily B member 9

1

4

High-throughput

0.479

High

373757

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

Small-scale

0.460

High

199675

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.458

High

205091

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

216184

CALU
Calumenin

1

0

High-throughput

0.458

High

335051

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.458

High

386171

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

445291

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

501735

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.458

High

556787

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

674630

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.458

High

674636

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

674638

EFNA4
Ephrin-A4

1

0

High-throughput

0.458

High

674644

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

674652

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

674661

CUL3
Cullin-3

1

0

High-throughput

0.458

High

674665

SRC8
Src substrate cortactin

1

0

High-throughput

0.458

High

674694

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

674706

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

674716

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

674725

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

674732

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

674735

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

297461

TOX4
TOX high mobility group box family member 4

1

1

High-throughput

0.437

High

674634

RBM25
RNA-binding protein 25

1

1

High-throughput

0.437

High

674672

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

High-throughput

0.437

High

674674

TECT1
Tectonic-1

1

1

High-throughput

0.437

High

674679

PR38B
Pre-mRNA-splicing factor 38B

1

1

High-throughput

0.437

High

674681

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

674692

PHF6
PHD finger protein 6

1

1

High-throughput

0.437

High

674698

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.437

High

674710

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

4

High-throughput

0.437

High

674719

DJC18
DnaJ homolog subfamily C member 18

1

3

High-throughput

0.437

High

674729

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.437

High

674736

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

496395

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

674643

CD81
CD81 antigen

1

0

High-throughput

0.426

High

674708

LCOR
Ligand-dependent corepressor

2

0

High-throughput

0.328

High

674635

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.282

High

674663

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.282

High

674740

ETV7
Transcription factor ETV7

1

0

High-throughput

0.282

High

154466

MEIS2
Homeobox protein Meis2

1

0

High-throughput

0.279

Low

236702

CCNT1
Cyclin-T1

1

0

High-throughput

0.279

Low

674628

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.279

Low

674655

TP53B
TP53-binding protein 1

1

0

High-throughput

0.279

Low

674658

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.279

Low

674666

CAPR1
Caprin-1

1

0

High-throughput

0.279

Low

674687

PCLI1
PTB-containing, cubilin and LRP1-interacting protein

1

0

High-throughput

0.279

Low

674690

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

0

High-throughput

0.279

Low

674691

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

674695

MICU2
Calcium uptake protein 2, mitochondrial

1

0

High-throughput

0.279

Low

674696

AN36B
Ankyrin repeat domain-containing protein 36B

1

0

High-throughput

0.279

Low

674722

JADE2
E3 ubiquitin-protein ligase Jade-2

1

0

High-throughput

0.279

Low

674730

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.279

Low

674738

CBPC1
Cytosolic carboxypeptidase 1

1

0

High-throughput

0.269

Low

92167

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.249

Low

133337

NOP56
Nucleolar protein 56

1

0

High-throughput

0.249

Low

202381

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.249

Low

214862

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.249

Low

313509

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

0

High-throughput

0.249

Low

508355

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.249

Low

525431

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.249

Low

595582

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.249

Low

632615

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.249

Low

674629

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.249

Low

674637

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

674640

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.249

Low

674645

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

674646

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.249

Low

674647

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.249

Low

674648

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

674649

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.249

Low

674659

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.249

Low

674660

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.249

Low

674664

ELOA1
Elongin-A

1

0

High-throughput

0.249

Low

674667

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.249

Low

674670

SF3B4
Splicing factor 3B subunit 4

1

0

High-throughput

0.249

Low

674671

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.249

Low

674673

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.249

Low

674675

FA76B
Protein FAM76B

1

0

High-throughput

0.249

Low

674677

CI114
Putative methyltransferase C9orf114

1

0

High-throughput

0.249

Low

674682

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.249

Low

674683

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.249

Low

674684

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

674685

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

674686

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

674688

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.249

Low

674689

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.249

Low

674697

NGEF
Ephexin-1

1

0

High-throughput

0.249

Low

674699

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.249

Low

674702

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.249

Low

674703

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.249

Low

674704

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

674707

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.249

Low

674711

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.249

Low

674714

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.249

Low

674715

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

674717

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.249

Low

674718

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.249

Low

674724

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

674726

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.249

Low

674727

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.249

Low

674739

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.249

Low

176127

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.238

Low

674642

SUMO3
Small ubiquitin-related modifier 3

1

0

Small-scale

0.232

Low

674680

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024