Protein: CCHL
Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase)

Gene: CCHL, HCCS
Organism: Homo sapiens
Interactions: 101
UniProt ID: P53701

Gene Ontology (top 5):
GO:0004408 - holocytochrome-c synthase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
GO:0009887 - animal organ morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864254

PHF23
PHD finger protein 23

4

0

High-throughput

0.670

High

864280

FZR1
Fizzy-related protein homolog

4

0

High-throughput

0.664

High

238158

PLIN3
Perilipin-3

3

0

High-throughput

0.638

High

441102

CY1
Cytochrome c1, heme protein, mitochondrial

3

0

High-throughput

0.638

High

864240

TADA1
Transcriptional adapter 1

3

0

High-throughput

0.638

High

864243

RRFM
Ribosome-recycling factor, mitochondrial

3

0

High-throughput

0.638

High

864264

MARH7
E3 ubiquitin-protein ligase MARCHF7

3

0

High-throughput

0.638

High

864276

ARMX3
Armadillo repeat-containing X-linked protein 3

3

0

High-throughput

0.638

High

864220

AGK
Acylglycerol kinase, mitochondrial

2

0

High-throughput

0.602

High

864233

ASCC3
Activating signal cointegrator 1 complex subunit 3

2

0

High-throughput

0.595

High

864269

M1IP1
Mid1-interacting protein 1

2

0

High-throughput

0.585

High

864278

GPTC8
G patch domain-containing protein 8

2

0

High-throughput

0.585

High

325103

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

1

High-throughput

0.584

High

864215

SNX1
Sorting nexin-1

2

0

High-throughput

0.580

High

864268

SENP2
Sentrin-specific protease 2

2

0

High-throughput

0.580

High

864277

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.580

High

352751

IFNA1
Interferon alpha-1/13

2

1

High-throughput

0.574

High

352800

IFN21
Interferon alpha-21

2

1

High-throughput

0.574

High

864228

SNX20
Sorting nexin-20

2

1

High-throughput

0.574

High

525464

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

864265

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

864211

RRAS2
Ras-related protein R-Ras2

1

1

High-throughput

0.536

High

864281

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

1

High-throughput

0.536

High

217304

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

452158

CD7
T-cell antigen CD7

1

0

High-throughput

0.513

High

864213

CYC
Cytochrome c

1

0

High-throughput

0.513

High

864225

CRTC3
CREB-regulated transcription coactivator 3

1

0

High-throughput

0.513

High

864226

CERS6
Ceramide synthase 6

1

0

High-throughput

0.513

High

864238

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

864253

CHCH5
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5

1

0

High-throughput

0.513

High

864262

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

864270

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

864272

RM17
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.513

High

864274

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.513

High

864234

CLRN3
Clarin-3

1

0

High-throughput

0.493

High

864283

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

864209

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.479

High

864210

RAB14
Ras-related protein Rab-14

1

1

High-throughput

0.479

High

864258

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

864273

ARL8B
ADP-ribosylation factor-like protein 8B

1

1

High-throughput

0.479

High

864279

RAB21
Ras-related protein Rab-21

1

1

High-throughput

0.479

High

864286

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

119275

LEG9
Galectin-9

1

0

High-throughput

0.458

High

130470

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

258422

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

274515

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

276804

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

602510

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.458

High

864212

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

864218

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

864223

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

864230

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

864236

ATLA2
Atlastin-2

1

0

High-throughput

0.458

High

864239

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.458

High

864242

OPTN
Optineurin

1

0

High-throughput

0.458

High

864244

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

864245

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

0

High-throughput

0.458

High

864246

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

864247

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

864249

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

864250

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

864251

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.458

High

864252

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.458

High

864255

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

864257

SHRPN
Sharpin

1

0

Small-scale

0.458

High

864259

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

864266

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.458

High

864227

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

864235

MROH1
Maestro heat-like repeat-containing protein family member 1

1

1

High-throughput

0.437

High

789220

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

864231

TRXR3
Thioredoxin reductase 3

1

0

High-throughput

0.426

High

92495

E9PHY8
Maestro heat like repeat family member 1

1

1

High-throughput

0.407

High

311056

MPZL1
Myelin protein zero-like protein 1

3

0

High-throughput

0.347

High

864217

NPAT
Protein NPAT

3

0

High-throughput

0.347

High

864232

MET16
RNA N6-adenosine-methyltransferase METTL16

3

0

High-throughput

0.347

High

864241

F136A
Protein FAM136A

3

0

High-throughput

0.347

High

864271

KCNQ5
Potassium voltage-gated channel subfamily KQT member 5

3

0

High-throughput

0.347

High

519707

MYCL
Protein L-Myc

2

0

High-throughput

0.328

High

674782

GRPR
Gastrin-releasing peptide receptor

2

0

High-throughput

0.328

High

864263

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.328

High

864221

CA220
Putative uncharacterized protein C1orf220

2

0

High-throughput

0.288

High

351150

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

864214

TNR9
Tumor necrosis factor receptor superfamily member 9

1

0

High-throughput

0.279

Low

864222

HES3
Transcription factor HES-3

1

0

High-throughput

0.279

Low

864229

GGN
Gametogenetin

1

0

High-throughput

0.279

Low

864248

FCRL4
Fc receptor-like protein 4

1

0

High-throughput

0.279

Low

864285

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

413131

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

375724

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.249

Low

569451

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

864216

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

864219

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

864224

TR3N
Putative uncharacterized protein TXNRD3NB

1

0

High-throughput

0.249

Low

864237

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.249

Low

864256

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.249

Low

864260

TMX1
Thioredoxin-related transmembrane protein 1

1

0

High-throughput

0.249

Low

864261

SG196
Protein O-mannose kinase

1

0

High-throughput

0.249

Low

864267

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

864275

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

864282

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

864284

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024