Protein: THIOM
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)

Gene: THIOM, Txn2
Organism: Mus musculus
Interactions: 171
UniProt ID: P97493

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0015035 - protein-disulfide reductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021679

THIOM
Thioredoxin, mitochondrial

1

18

High-throughput

0.618

High

148100

PRDX6
Peroxiredoxin-6

1

20

High-throughput

0.575

High

148340

PRDX4
Peroxiredoxin-4

1

20

High-throughput

0.575

High

628294

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

20

High-throughput

0.575

High

776005

PRDX1
Peroxiredoxin-1

1

20

High-throughput

0.575

High

1021680

PRDX5
Peroxiredoxin-5, mitochondrial

1

6

High-throughput

0.575

High

1021693

PRDX2
Peroxiredoxin-2

1

20

High-throughput

0.575

High

1021746

MSRA
Mitochondrial peptide methionine sulfoxide reductase

1

4

High-throughput

0.575

High

205519

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

High-throughput

0.514

High

597649

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

4

High-throughput

0.514

High

635056

TNNC2
Troponin C, skeletal muscle

1

2

High-throughput

0.514

High

997221

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.514

High

1021691

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

High-throughput

0.514

High

1021703

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.514

High

1021706

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

5

High-throughput

0.514

High

1021717

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

High-throughput

0.514

High

1021735

PLST
Plastin-3

1

7

High-throughput

0.514

High

1021743

ERP44
Endoplasmic reticulum resident protein 44

1

17

High-throughput

0.514

High

1021761

MLRA
Myosin regulatory light chain 2, atrial isoform

1

4

High-throughput

0.514

High

1021768

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

3

High-throughput

0.514

High

1021687

ST1D1
Sulfotransferase 1 family member D1

1

0

High-throughput

0.481

High

147495

DPYL2
Dihydropyrimidinase-related protein 2

1

2

High-throughput

0.445

High

313073

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

2

High-throughput

0.445

High

439027

LDHA
L-lactate dehydrogenase A chain

1

8

High-throughput

0.445

High

596907

ASSY
Argininosuccinate synthase

1

1

High-throughput

0.445

High

598661

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

9

High-throughput

0.445

High

663471

CRYAB
Alpha-crystallin B chain

1

2

High-throughput

0.445

High

801615

HSPA9
Stress-70 protein, mitochondrial

1

13

High-throughput

0.445

High

866539

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

4

High-throughput

0.445

High

896006

VATA
V-type proton ATPase catalytic subunit A

1

10

High-throughput

0.445

High

940812

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

1

8

High-throughput

0.445

High

972205

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

981756

RAN
GTP-binding nuclear protein Ran

1

3

High-throughput

0.445

High

989437

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.445

High

993962

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.445

High

1000373

IDHG1
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial

1

3

High-throughput

0.445

High

1021682

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

8

High-throughput

0.445

High

1021700

KCRS
Creatine kinase S-type, mitochondrial

1

2

High-throughput

0.445

High

1021701

SYNE2
Nesprin-2

1

3

High-throughput

0.445

High

1021704

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

1021705

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.445

High

1021709

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.445

High

1021714

MIC60
MICOS complex subunit Mic60

1

2

High-throughput

0.445

High

1021715

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

6

High-throughput

0.445

High

1021718

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

1

4

High-throughput

0.445

High

1021720

ERO1A
ERO1-like protein alpha

1

9

High-throughput

0.445

High

1021723

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.445

High

1021728

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

2

High-throughput

0.445

High

1021729

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

4

High-throughput

0.445

High

1021730

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

1

High-throughput

0.445

High

1021736

ACON
Aconitate hydratase, mitochondrial

1

4

High-throughput

0.445

High

1021737

PARK7
Parkinson disease protein 7 homolog

1

4

High-throughput

0.445

High

1021738

ACS2L
Acetyl-coenzyme A synthetase 2-like, mitochondrial

1

2

High-throughput

0.445

High

1021741

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

7

High-throughput

0.445

High

1021745

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

3

High-throughput

0.445

High

1021751

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.445

High

1021753

ECHP
Peroxisomal bifunctional enzyme

1

2

High-throughput

0.445

High

1021755

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

2

High-throughput

0.445

High

1021765

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.445

High

660955

IRF8
Interferon regulatory factor 8

1

1

High-throughput

0.437

High

550017

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.426

High

567617

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.426

High

977436

RS4X
Small ribosomal subunit protein eS4

1

0

High-throughput

0.426

High

1021685

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.426

High

1021698

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.426

High

1021733

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.426

High

1021734

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.426

High

1021740

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.426

High

1021754

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.426

High

72998

B1AQ77
Keratin 15

1

2

High-throughput

0.407

High

148779

SODE
Extracellular superoxide dismutase [Cu-Zn]

1

10

High-throughput

0.407

High

204486

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

2

High-throughput

0.407

High

237180

SEPT7
Septin-7

1

2

High-throughput

0.407

High

380787

HBB1
Hemoglobin subunit beta-1

1

4

High-throughput

0.407

High

380800

HBB2
Hemoglobin subunit beta-2

1

4

High-throughput

0.407

High

421222

ALDOA
Fructose-bisphosphate aldolase A

1

7

High-throughput

0.407

High

437609

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

2

High-throughput

0.407

High

456040

KCRM
Creatine kinase M-type

1

2

High-throughput

0.407

High

456911

ANXA2
Annexin A2

1

6

High-throughput

0.407

High

547942

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.407

High

559568

GELS
Gelsolin

1

1

High-throughput

0.407

High

571097

RSSA
Small ribosomal subunit protein uS2

1

4

High-throughput

0.407

High

572878

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.407

High

590977

LEG1
Galectin-1

1

9

High-throughput

0.407

High

602919

ENOA
Alpha-enolase

1

6

High-throughput

0.407

High

605431

SBP1
Methanethiol oxidase

1

1

High-throughput

0.407

High

607874

TPIS
Triosephosphate isomerase

1

3

High-throughput

0.407

High

616471

COF1
Cofilin-1

1

2

High-throughput

0.407

High

628492

VIME
Vimentin

1

5

High-throughput

0.407

High

638868

ENOB
Beta-enolase

1

6

High-throughput

0.407

High

665771

AL1A1
Aldehyde dehydrogenase 1A1

1

4

High-throughput

0.407

High

683920

TLN1
Talin-1

1

3

High-throughput

0.407

High

705680

MEP1A
Meprin A subunit alpha

1

5

High-throughput

0.407

High

837990

SEPT2
Septin-2

1

2

High-throughput

0.407

High

858743

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.407

High

866572

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.407

High

866592

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.407

High

900611

ICAL
Calpastatin

1

3

High-throughput

0.407

High

940711

CDD
Cytidine deaminase

1

1

High-throughput

0.407

High

945614

ACTN4
Alpha-actinin-4

1

2

High-throughput

0.407

High

946728

TB182
182 kDa tankyrase-1-binding protein

1

2

High-throughput

0.407

High

949807

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.407

High

953235

ACTB
Actin, cytoplasmic 1

1

8

High-throughput

0.407

High

958549

ACTZ
Alpha-centractin

1

10

High-throughput

0.407

High

965990

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

4

High-throughput

0.407

High

973014

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.407

High

977874

ACTA
Actin, aortic smooth muscle

1

8

High-throughput

0.407

High

981243

VATB2
V-type proton ATPase subunit B, brain isoform

1

10

High-throughput

0.407

High

995927

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.407

High

996570

ACTS
Actin, alpha skeletal muscle

1

8

High-throughput

0.407

High

1000367

MYBPH
Myosin-binding protein H

1

7

High-throughput

0.407

High

1000426

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

6

High-throughput

0.407

High

1021462

MYL11
Myosin regulatory light chain 11

1

4

High-throughput

0.407

High

1021681

RSU1
Ras suppressor protein 1

1

1

High-throughput

0.407

High

1021683

CNN2
Calponin-2

1

8

High-throughput

0.407

High

1021688

Q5M8R7
Ldhb protein

1

2

High-throughput

0.407

High

1021689

MYPC2
Myosin-binding protein C, fast-type

1

9

High-throughput

0.407

High

1021690

SRC8
Src substrate cortactin

1

5

High-throughput

0.407

High

1021692

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.407

High

1021695

LASP1
LIM and SH3 domain protein 1

1

5

High-throughput

0.407

High

1021696

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.407

High

1021697

MYOM1
Myomesin-1

1

6

High-throughput

0.407

High

1021699

SBP2
Selenium-binding protein 2

1

1

High-throughput

0.407

High

1021707

Q8BIL4
Uncharacterized protein

1

2

High-throughput

0.407

High

1021708

DUS29
Dual specificity phosphatase 29

1

5

High-throughput

0.407

High

1021710

Q8BRB8
PDZ domain-containing protein

1

2

High-throughput

0.407

High

1021711

FLNA
Filamin-A

1

12

High-throughput

0.407

High

1021712

SEP11
Septin-11

1

2

High-throughput

0.407

High

1021716

CBR3
Carbonyl reductase [NADPH] 3

1

2

High-throughput

0.407

High

1021719

Q8R112
Ttn protein

1

6

High-throughput

0.407

High

1021722

ACY2
Aspartoacylase

1

1

High-throughput

0.407

High

1021724

TXLNB
Beta-taxilin

1

3

High-throughput

0.407

High

1021725

Q8VCQ8
Caldesmon 1

1

2

High-throughput

0.407

High

1021726

MYH9
Myosin-9

1

1

High-throughput

0.407

High

1021727

VIGLN
Vigilin

1

5

High-throughput

0.407

High

1021731

ACY3
N-acyl-aromatic-L-amino acid amidohydrolase

1

1

High-throughput

0.407

High

1021732

TWF1
Twinfilin-1

1

2

High-throughput

0.407

High

1021742

ILEUA
Leukocyte elastase inhibitor A

1

2

High-throughput

0.407

High

1021747

DUS3
Dual specificity protein phosphatase 3

1

5

High-throughput

0.407

High

1021748

IPYR
Inorganic pyrophosphatase

1

4

High-throughput

0.407

High

1021749

CNN3
Calponin-3

1

8

High-throughput

0.407

High

1021756

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

6

High-throughput

0.407

High

1021757

Q9JHR4
Myosin heavy chain IIB

1

2

High-throughput

0.407

High

1021758

Q9JHV3
Klra19 protein

1

3

High-throughput

0.407

High

1021759

MYOTI
Myotilin

1

6

High-throughput

0.407

High

1021760

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

6

High-throughput

0.407

High

1021762

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

9

High-throughput

0.407

High

1021763

DEST
Destrin

1

2

High-throughput

0.407

High

1021766

RUVB2
RuvB-like 2

1

1

High-throughput

0.407

High

1021767

CCS
Copper chaperone for superoxide dismutase

1

10

High-throughput

0.407

High

94508

D6RJ85
RNA binding motif protein 39

1

0

High-throughput

0.232

Low

98225

E9Q851
Rac GTPase-activating protein 1

1

0

High-throughput

0.232

Low

236709

AKAP2
PALM2-AKAP2 fusion protein

1

0

High-throughput

0.232

Low

459384

ALBU
Albumin

1

0

High-throughput

0.232

Low

590776

CAH3
Carbonic anhydrase 3

1

0

High-throughput

0.232

Low

627182

LSP1
Lymphocyte-specific protein 1

1

0

High-throughput

0.232

Low

829041

INMT
Indolethylamine N-methyltransferase

1

0

High-throughput

0.232

Low

867926

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.232

Low

925784

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.232

Low

1021684

UAP1L
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1

1

0

High-throughput

0.232

Low

1021686

Q3UWR0
PWWP domain-containing protein

1

0

High-throughput

0.232

Low

1021694

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.232

Low

1021702

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

0

High-throughput

0.232

Low

1021713

CA198
Uncharacterized protein C1orf198 homolog

1

0

High-throughput

0.232

Low

1021721

Q8R1X5
Edem3 protein

1

0

High-throughput

0.232

Low

1021739

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.232

Low

1021744

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.232

Low

1021750

IAH1
Isoamyl acetate-hydrolyzing esterase 1 homolog

1

0

High-throughput

0.232

Low

1021752

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

0

High-throughput

0.232

Low

1021764

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025