Protein: FAK2
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)

Gene: FAK2, Ptk2b
Organism: Mus musculus
Interactions: 31
UniProt ID: Q9QVP9

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001525 - angiogenesis
GO:0001556 - oocyte maturation
GO:0001666 - response to hypoxia
GO:0001954 - positive regulation of cell-matrix adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1351539

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

20

Small-scale

0.756

High

403463

SRC
Proto-oncogene tyrosine-protein kinase Src

2

20

Small-scale

0.754

High

93651

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

20

Small-scale

0.724

High

1113255

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

Small-scale

0.647

High

222883

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.618

High

562605

IL7RA
Interleukin-7 receptor subunit alpha

1

2

Small-scale

0.618

High

956526

DOK1
Docking protein 1

1

20

Small-scale

0.618

High

995950

EPS8
Epidermal growth factor receptor kinase substrate 8

1

20

Small-scale

0.618

High

1112655

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

20

High-throughput

0.618

High

1142640

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.618

High

1167905

RHG10
Rho GTPase-activating protein 10

1

20

Small-scale

0.618

High

1246754

BFAR
Bifunctional apoptosis regulator

1

11

Small-scale

0.618

High

1257660

PAXI
Paxillin

1

20

Small-scale

0.618

High

554948

KPCE
Protein kinase C epsilon type

1

20

Small-scale

0.575

High

1206693

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

20

High-throughput

0.575

High

193358

SOCS1
Suppressor of cytokine signaling 1

1

20

Small-scale

0.555

High

723614

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

14

High-throughput

0.536

High

100099

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

20

High-throughput

0.479

High

103263

G3X9H5
Huntingtin

1

6

High-throughput

0.479

High

356894

P53
Cellular tumor antigen p53

1

9

Small-scale

0.479

High

956935

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

17

Small-scale

0.479

High

963774

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

14

High-throughput

0.479

High

1111707

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

1145301

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

6

High-throughput

0.479

High

1194228

FACD2
Fanconi anemia group D2 protein homolog

1

7

High-throughput

0.479

High

1207243

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

20

Small-scale

0.479

High

1265602

EED
Polycomb protein EED

1

7

High-throughput

0.479

High

1307900

LPXN
Leupaxin

1

20

Small-scale

0.479

High

886831

NPHP4
Nephrocystin-4

1

2

Small-scale

0.437

High

1257648

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.426

High

1322252

XPO7
Exportin-7

1

5

High-throughput

0.407

High


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Last updated: 15 Jul 2024