Protein: KLOT
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]

Gene: KLOT, Kl
Organism: Mus musculus
Interactions: 11
UniProt ID: O35082

Gene Ontology (top 5):
GO:0003085 - negative regulation of systemic arterial blood pressure
GO:0004566 - beta-glucuronidase activity
GO:0005104 - fibroblast growth factor receptor binding
GO:0005576 - extracellular region
GO:0005975 - carbohydrate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

204195

FGFR1
Fibroblast growth factor receptor 1

2

11

Small-scale

0.767

High

204201

FGFR4
Fibroblast growth factor receptor 4

2

11

Small-scale

0.767

High

204202

FGFR3
Fibroblast growth factor receptor 3

1

11

Small-scale

0.646

High

98382

E9QNJ9
Fibroblast growth factor receptor

1

11

Small-scale

0.618

High

204197

FGFR2
Fibroblast growth factor receptor 2

1

11

Small-scale

0.618

High

204194

WNT1
Proto-oncogene Wnt-1

1

3

Small-scale

0.479

High

204196

WNT3
Proto-oncogene Wnt-3

1

3

Small-scale

0.479

High

204198

WNT4
Protein Wnt-4

1

3

Small-scale

0.479

High

204199

WNT5A
Protein Wnt-5a

1

3

Small-scale

0.479

High

204203

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

Small-scale

0.479

High

204200

TRPV5
Transient receptor potential cation channel subfamily V member 5

1

0

Small-scale

0.458

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025