Protein: RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2)

Gene: RGPS2, RALGPS2
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q86X27

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

349443

RASH
GTPase HRas

2

20

High-throughput

0.754

High

683515

1433B
14-3-3 protein beta/alpha

7

20

High-throughput

0.749

High

927257

1433Z
14-3-3 protein zeta/delta

6

20

High-throughput

0.739

High

904810

1433G
14-3-3 protein gamma

6

20

High-throughput

0.738

High

982233

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

647073

1433T
14-3-3 protein theta

4

20

High-throughput

0.697

High

230890

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

6

High-throughput

0.618

High

253377

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

1

High-throughput

0.618

High

348758

RASN
GTPase NRas

1

20

High-throughput

0.618

High

350308

RASK
GTPase KRas

1

20

High-throughput

0.618

High

1136461

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

6

High-throughput

0.618

High

1136521

SPD2A
SH3 and PX domain-containing protein 2A

1

16

High-throughput

0.618

High

1203937

KSR1
Kinase suppressor of Ras 1

1

3

High-throughput

0.618

High

1203945

KI13B
Kinesin-like protein KIF13B

1

3

High-throughput

0.618

High

909770

1433E
14-3-3 protein epsilon

2

4

High-throughput

0.611

High

1203943

OSBL3
Oxysterol-binding protein-related protein 3

2

1

High-throughput

0.606

High

684179

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

997182

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

2

High-throughput

0.553

High

1203939

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

13

High-throughput

0.553

High

1203941

RTKN
Rhotekin

1

0

High-throughput

0.517

High

325261

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.493

High

196473

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.479

High

598494

NF1
Neurofibromin

1

2

High-throughput

0.479

High

673600

MPIP3
M-phase inducer phosphatase 3

1

2

High-throughput

0.479

High

880772

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

1020189

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

9

High-throughput

0.479

High

1139611

DEN4C
DENN domain-containing protein 4C

1

1

High-throughput

0.479

High

1203938

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.479

High

1203942

OSBL6
Oxysterol-binding protein-related protein 6

1

1

High-throughput

0.479

High

1203946

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

2

High-throughput

0.479

High

1203948

CING
Cingulin

1

1

High-throughput

0.479

High

1203951

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.479

High

1203953

KCTD3
BTB/POZ domain-containing protein KCTD3

1

3

High-throughput

0.479

High

237257

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

347220

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

1203947

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.458

High

264349

GGYF1
GRB10-interacting GYF protein 1

1

4

High-throughput

0.437

High

1167916

GGYF2
GRB10-interacting GYF protein 2

1

6

High-throughput

0.437

High

1201523

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.437

High

1203944

TANC2
Protein TANC2

1

6

High-throughput

0.437

High

1203949

NGAP
Ras GTPase-activating protein nGAP

1

2

High-throughput

0.437

High

316263

NADK
NAD kinase

1

0

High-throughput

0.249

Low

1203940

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.249

Low

1203950

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.249

Low

1203952

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024