Protein: COX5A
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)

Gene: COX5A
Organism: Homo sapiens
Interactions: 160
UniProt ID: P20674

Gene Ontology (top 5):
GO:0004129 - cytochrome-c oxidase activity
GO:0005743 - mitochondrial inner membrane
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0009055 - electron transfer activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

525415

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

4

1

High-throughput

0.895

High

454003

COX6C
Cytochrome c oxidase subunit 6C

2

0

Small-scale

0.699

High

594951

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

1

High-throughput

0.691

High

594874

VDAC1
Voltage-dependent anion-selective channel protein 1

2

1

High-throughput

0.611

High

147655

COX7R
Cytochrome c oxidase subunit 7A-related protein, mitochondrial

2

0

High-throughput

0.602

High

594917

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

2

0

High-throughput

0.602

High

594990

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

2

0

Small-scale

0.547

High

335651

COX1
Cytochrome c oxidase subunit 1

1

1

High-throughput

0.536

High

594910

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.523

High

594916

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.523

High

368975

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

594889

RHOA
Transforming protein RhoA

2

2

High-throughput

0.521

High

197226

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.513

High

394103

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

557520

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

1

High-throughput

0.489

High

594891

RAC1
Ras-related C3 botulinum toxin substrate 1

1

2

High-throughput

0.489

High

594962

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.479

High

258402

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

264836

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

594895

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

594898

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

594911

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.479

High

594931

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

594937

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.479

High

594941

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

594947

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

594952

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.479

High

594953

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

594955

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

594966

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

594968

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

594976

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.479

High

594983

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

130435

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

203872

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

231056

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

274491

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

276784

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

325033

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

473374

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

579495

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.458

High

594899

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.458

High

594919

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

594924

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

594928

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

594946

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

594956

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.458

High

594958

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

594959

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

594960

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

594964

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

594965

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

594969

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

594971

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

594974

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

594975

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

594987

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

594991

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

594894

CX6A2
Cytochrome c oxidase subunit 6A2, mitochondrial

1

1

Small-scale

0.445

High

160377

AURKA
Aurora kinase A

1

1

High-throughput

0.437

High

269980

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.437

High

345911

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

377086

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

379009

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

594886

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.437

High

594887

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.437

High

594893

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.437

High

594927

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

594938

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

1

High-throughput

0.437

High

594939

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

594949

AURKB
Aurora kinase B

1

1

High-throughput

0.437

High

594970

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.437

High

594980

DNJC4
DnaJ homolog subfamily C member 4

1

1

High-throughput

0.437

High

594986

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.437

High

594994

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.437

High

439062

ELNE
Neutrophil elastase

1

1

Small-scale

0.417

High

99556

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

594884

HD
Huntingtin

1

1

High-throughput

0.407

High

594989

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.407

High

594912

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

0

Small-scale

0.334

High

594900

G3BP1
Ras GTPase-activating protein-binding protein 1

2

0

High-throughput

0.328

High

309240

SPDEF
SAM pointed domain-containing Ets transcription factor

2

0

High-throughput

0.316

High

594906

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

262704

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.305

High

594942

EXOS8
Exosome complex component RRP43

1

0

High-throughput

0.299

High

594932

DOCK8
Dedicator of cytokinesis protein 8

2

0

High-throughput

0.298

High

594920

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.282

High

173431

RER1
Protein RER1

1

0

High-throughput

0.279

Low

235706

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.279

Low

343945

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.279

Low

594873

LMNB1
Lamin-B1

1

0

High-throughput

0.279

Low

594875

BRD2
Bromodomain-containing protein 2

1

0

High-throughput

0.279

Low

594877

BLVRB
Flavin reductase

1

0

High-throughput

0.279

Low

594878

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.279

Low

594907

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.279

Low

594921

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

594922

URP2
Fermitin family homolog 3

1

0

High-throughput

0.279

Low

594929

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.279

Low

594930

KDM1B
Lysine-specific histone demethylase 2

1

0

High-throughput

0.279

Low

594963

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

594967

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

594979

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.279

Low

594992

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

594993

RPGF2
Rap guanine nucleotide exchange factor 2

1

0

High-throughput

0.279

Low

594876

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.268

Low

310382

EPM2A
Laforin

1

0

Small-scale

0.251

Low

100469

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

209663

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

226505

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

327354

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.249

Low

569172

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

594879

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

594880

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.249

Low

594881

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

594883

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.249

Low

594885

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.249

Low

594888

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.249

Low

594890

H4
Histone H4

1

0

High-throughput

0.249

Low

594892

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.249

Low

594896

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.249

Low

594897

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.249

Low

594901

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.249

Low

594902

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

0

Small-scale

0.249

Low

594903

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

594904

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

594905

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

594908

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

594909

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

594913

MIDN
Midnolin

1

0

High-throughput

0.249

Low

594915

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

594918

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

594923

SL9A9
Sodium/hydrogen exchanger 9

1

0

Small-scale

0.249

Low

594925

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.249

Low

594926

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

594933

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.249

Low

594934

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

594935

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

594936

DUS19
Dual specificity protein phosphatase 19

1

0

High-throughput

0.249

Low

594940

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.249

Low

594943

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.249

Low

594944

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.249

Low

594945

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.249

Low

594950

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

594954

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.249

Low

594957

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

594961

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.249

Low

594972

OPA3
Optic atrophy 3 protein

1

0

High-throughput

0.249

Low

594973

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

594977

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

594978

LFG4
Protein lifeguard 4

1

0

High-throughput

0.249

Low

594981

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.249

Low

594982

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

594984

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.249

Low

594985

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

594988

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

594914

MYOME
Myomegalin

1

0

Small-scale

0.238

Low

377921

PRIO
Major prion protein

1

0

High-throughput

0.232

Low

496285

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.232

Low

594882

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

594948

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024