Protein: MRP1
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter)

Gene: MRP1, ABCC1
Organism: Homo sapiens
Interactions: 90
UniProt ID: P33527

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006691 - leukotriene metabolic process
GO:0006805 - xenobiotic metabolic process
GO:0008559 - ABC-type xenobiotic transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

706684

MRP1
Multidrug resistance-associated protein 1

2

7

Small-scale

0.825

High

349920

RASK
GTPase KRas

3

15

High-throughput

0.640

High

348537

RASN
GTPase NRas

2

15

High-throughput

0.584

High

349151

RASH
GTPase HRas

2

11

High-throughput

0.584

High

706700

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

706706

CAV1
Caveolin-1

2

3

Small-scale

0.584

High

636818

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

Small-scale

0.561

High

706704

CSK21
Casein kinase II subunit alpha

1

3

Small-scale

0.561

High

706691

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

119206

LEG9
Galectin-9

2

13

High-throughput

0.558

High

121117

LEG8
Galectin-8

1

13

High-throughput

0.536

High

572294

LEG3
Galectin-3

1

13

High-throughput

0.536

High

626732

NK1R
Substance-P receptor

1

1

High-throughput

0.536

High

706710

CD166
CD166 antigen

1

1

High-throughput

0.536

High

706719

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.536

High

706727

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

1

High-throughput

0.536

High

417976

NPM
Nucleophosmin

1

0

High-throughput

0.518

High

706707

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

0

High-throughput

0.513

High

706739

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.489

High

377135

GCR
Glucocorticoid receptor

1

7

Small-scale

0.481

High

629100

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.481

High

120319

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

126997

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

163757

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

171197

CTDSL
CTD small phosphatase-like protein

1

1

High-throughput

0.479

High

205099

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

318072

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.479

High

384365

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

390086

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

433613

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

436176

RHOC
Rho-related GTP-binding protein RhoC

1

16

High-throughput

0.479

High

506892

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

527316

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

545225

RAC2
Ras-related C3 botulinum toxin substrate 2

1

16

High-throughput

0.479

High

564426

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

566940

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

706686

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

706688

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.479

High

706689

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

706690

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

706692

RAC3
Ras-related C3 botulinum toxin substrate 3

1

18

High-throughput

0.479

High

706693

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

706694

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

706695

RHOA
Transforming protein RhoA

1

18

High-throughput

0.479

High

706696

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

706698

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

706699

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

706702

RAC1
Ras-related C3 botulinum toxin substrate 1

1

18

High-throughput

0.479

High

706703

EF1A1
Elongation factor 1-alpha 1

1

1

Small-scale

0.479

High

706705

RHOG
Rho-related GTP-binding protein RhoG

1

16

High-throughput

0.479

High

706711

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

706712

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

706714

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

706715

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

706717

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

706722

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

706723

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

706726

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

706728

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

706731

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

706732

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

706733

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

706737

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

178412

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

305371

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

648662

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

669895

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

706685

BASI
Basigin

1

0

High-throughput

0.458

High

706687

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

706701

H4
Histone H4

1

0

High-throughput

0.458

High

706713

OCLN
Occludin

1

0

High-throughput

0.458

High

706718

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.458

High

706725

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

706729

DERL1
Derlin-1

1

0

High-throughput

0.458

High

706708

TRAF3
TNF receptor-associated factor 3

1

1

High-throughput

0.439

High

706716

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

706720

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

706721

S15A3
Solute carrier family 15 member 3

1

2

High-throughput

0.437

High

706724

ESR2
Estrogen receptor beta

1

7

High-throughput

0.437

High

706736

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

706738

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

354325

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

706735

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

99562

F5H1C8
Solute carrier family 15 member 3

1

2

High-throughput

0.407

High

706730

UN93B
Protein unc-93 homolog B1

2

0

High-throughput

0.324

High

486471

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

706697

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

706709

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

706734

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024