Protein: GPI8
GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)

Gene: GPI8, PIGK
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q92643

Gene Ontology (top 5):
GO:0003756 - protein disulfide isomerase activity
GO:0003923 - GPI-anchor transamidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006508 - proteolysis
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

200051

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

7

1

Small-scale

0.742

High

1268708

PIGT
GPI transamidase component PIG-T

6

2

Small-scale

0.736

High

1268719

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

4

1

Small-scale

0.691

High

1268715

PIGS
GPI transamidase component PIG-S

4

1

Small-scale

0.683

High

310742

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

1

High-throughput

0.628

High

1268720

CST9L
Cystatin-9-like

1

3

High-throughput

0.618

High

654622

CALX
Calnexin

2

2

Small-scale

0.611

High

370125

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1268718

KLK15
Kallikrein-15

1

2

High-throughput

0.536

High

1268726

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

1268730

FBX2
F-box only protein 2

1

3

High-throughput

0.536

High

228237

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.533

High

123675

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.513

High

149698

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

295753

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.513

High

502388

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

833289

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

1014279

BST2
Bone marrow stromal antigen 2

1

0

High-throughput

0.513

High

1185612

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1268710

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1268717

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1268722

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

606919

IDS
Iduronate 2-sulfatase

1

1

High-throughput

0.489

High

1268709

T106A
Transmembrane protein 106A

1

1

High-throughput

0.489

High

377550

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

1217062

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.479

High

1268712

PLD4
5'-3' exonuclease PLD4

1

1

High-throughput

0.479

High

1268714

CALR3
Calreticulin-3

1

2

High-throughput

0.479

High

1268724

FBX6
F-box only protein 6

1

3

High-throughput

0.479

High

1268729

TSP50
Probable threonine protease PRSS50

1

2

High-throughput

0.479

High

390424

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

531927

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

900757

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

935059

H31
Histone H3.1

1

0

High-throughput

0.458

High

1168616

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1236935

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1268711

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1241553

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

205775

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

1171056

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1222059

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1268707

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1268721

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1268723

RHOF
Rho-related GTP-binding protein RhoF

1

1

High-throughput

0.437

High

1268725

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

99646

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

310330

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.318

High

398562

PPB1
Alkaline phosphatase, placental type

2

0

Small-scale

0.310

High

180141

SIA8E
Alpha-2,8-sialyltransferase 8E

1

0

High-throughput

0.279

Low

326162

TSN15
Tetraspanin-15

1

0

High-throughput

0.279

Low

380187

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.279

Low

533025

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

540324

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.279

Low

566441

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.279

Low

607703

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.279

Low

1265923

CLC2B
C-type lectin domain family 2 member B

1

0

High-throughput

0.279

Low

1268616

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.279

Low

1268713

CPNE2
Copine-2

1

0

High-throughput

0.279

Low

1268727

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

308942

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.249

Low

374626

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

553329

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

651839

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721059

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

845129

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

941248

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1029689

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1053625

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1101199

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1156656

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

1220949

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1231463

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1268716

ULBP2
UL16-binding protein 2

1

0

Small-scale

0.249

Low

1268728

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1268731

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.249

Low

517389

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.238

Low

209271

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low

1123537

HS904
Putative heat shock protein HSP 90-alpha A4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024