Protein: AP3S1
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)

Gene: AP3S1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q92572

Gene Ontology (top 5):
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0008089 - anterograde axonal transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150247

AP3D1
AP-3 complex subunit delta-1

6

20

Small-scale

0.946

High

120009

AP3B1
AP-3 complex subunit beta-1

2

20

High-throughput

0.811

High

864052

AP3M2
AP-3 complex subunit mu-2

2

20

High-throughput

0.811

High

1032730

AP3B2
AP-3 complex subunit beta-2

2

20

High-throughput

0.811

High

1267501

AP3M1
AP-3 complex subunit mu-1

2

20

High-throughput

0.811

High

207565

RNF13
E3 ubiquitin-protein ligase RNF13

4

4

Small-scale

0.703

High

1267480

DTBP1
Dysbindin

3

2

High-throughput

0.667

High

1267495

KLK11
Kallikrein-11

3

1

High-throughput

0.667

High

299191

CSCL1
CSC1-like protein 1

2

2

High-throughput

0.628

High

1267491

AGO3
Protein argonaute-3

3

2

High-throughput

0.609

High

1267498

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

1

High-throughput

0.609

High

1121315

AGK
Acylglycerol kinase, mitochondrial

2

0

High-throughput

0.602

High

1113963

RABL6
Rab-like protein 6

2

1

High-throughput

0.574

High

1204444

FBX11
F-box only protein 11

2

1

High-throughput

0.574

High

1231930

MUC20
Mucin-20

2

2

High-throughput

0.574

High

1267489

RN167
E3 ubiquitin-protein ligase RNF167

2

4

High-throughput

0.574

High

1267500

E41L3
Band 4.1-like protein 3

2

6

High-throughput

0.574

High

1068486

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.571

High

1267502

KLK5
Kallikrein-5

2

1

High-throughput

0.558

High

1267486

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.536

High

1267494

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

6

High-throughput

0.536

High

1267497

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

5

High-throughput

0.536

High

1267499

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.536

High

408653

KPCB
Protein kinase C beta type

2

2

High-throughput

0.521

High

498320

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

2

High-throughput

0.521

High

850757

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

6

High-throughput

0.521

High

983884

KPCZ
Protein kinase C zeta type

2

3

High-throughput

0.521

High

1234539

SH2D3
SH2 domain-containing protein 3C

2

12

High-throughput

0.521

High

441028

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.513

High

778588

PMEL
Melanocyte protein PMEL

1

0

High-throughput

0.513

High

724555

IRS1
Insulin receptor substrate 1

1

2

Small-scale

0.501

High

1267481

RUFY1
RUN and FYVE domain-containing protein 1

1

7

Small-scale

0.501

High

123674

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.489

High

400092

ICAM1
Intercellular adhesion molecule 1

1

2

High-throughput

0.489

High

452843

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

3

High-throughput

0.489

High

846505

BLK
Tyrosine-protein kinase Blk

1

4

High-throughput

0.489

High

1055959

ZN460
Zinc finger protein 460

1

1

High-throughput

0.489

High

1062603

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.489

High

1067559

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.489

High

1204506

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.489

High

1232263

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

2

High-throughput

0.489

High

1233129

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.489

High

1239942

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.489

High

1246099

TPC2
Two pore channel protein 2

1

2

High-throughput

0.489

High

1267484

NUAK2
NUAK family SNF1-like kinase 2

1

1

High-throughput

0.489

High

1267488

WDR55
WD repeat-containing protein 55

1

1

High-throughput

0.489

High

1267492

CHODL
Chondrolectin

1

2

High-throughput

0.489

High

163067

XPO1
Exportin-1

1

15

High-throughput

0.479

High

228227

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

527672

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

574721

ARF4
ADP-ribosylation factor 4

1

10

High-throughput

0.479

High

674490

UFO
Tyrosine-protein kinase receptor UFO

1

13

High-throughput

0.479

High

882466

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

897392

ARF3
ADP-ribosylation factor 3

1

10

High-throughput

0.479

High

913025

ARF6
ADP-ribosylation factor 6

1

10

High-throughput

0.479

High

950672

ARF5
ADP-ribosylation factor 5

1

10

High-throughput

0.479

High

1064540

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1188333

ATG9A
Autophagy-related protein 9A

1

7

High-throughput

0.479

High

1222057

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.479

High

1267479

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.479

High

1267496

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1267504

SRPRB
Signal recognition particle receptor subunit beta

1

12

High-throughput

0.479

High

1048361

SCRB2
Lysosome membrane protein 2

1

1

Small-scale

0.457

High

497365

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

295070

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

301946

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

High-throughput

0.437

High

322940

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.437

High

324855

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

6

High-throughput

0.437

High

338777

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.437

High

347464

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

411808

LCK
Tyrosine-protein kinase Lck

1

4

High-throughput

0.437

High

553317

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

651824

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

659308

DUS1
Dual specificity protein phosphatase 1

1

7

High-throughput

0.437

High

721044

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

729324

VGFR3
Vascular endothelial growth factor receptor 3

1

4

High-throughput

0.437

High

824233

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

908897

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.437

High

941243

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

985190

DUS2
Dual specificity protein phosphatase 2

1

7

High-throughput

0.437

High

1024818

DUS4
Dual specificity protein phosphatase 4

1

7

High-throughput

0.437

High

1026496

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.437

High

1029685

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

1086153

DUS5
Dual specificity protein phosphatase 5

1

7

High-throughput

0.437

High

1086691

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.437

High

1088028

DUS6
Dual specificity protein phosphatase 6

1

8

High-throughput

0.437

High

1146679

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

1148698

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1152010

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

1171041

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1259407

DUS19
Dual specificity protein phosphatase 19

1

8

High-throughput

0.437

High

1267482

DUS23
Dual specificity protein phosphatase 23

1

10

High-throughput

0.437

High

1267487

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1267490

ECT2
Protein ECT2

1

4

High-throughput

0.437

High

1267493

SP110
Sp110 nuclear body protein

1

4

High-throughput

0.437

High

1239838

GOLM1
Golgi membrane protein 1

1

0

Small-scale

0.426

High

99645

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1140470

BTBD8
BTB/POZ domain-containing protein 8

1

3

High-throughput

0.407

High

328300

IGSF6
Immunoglobulin superfamily member 6

2

0

High-throughput

0.328

High

1030105

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

2

0

High-throughput

0.328

High

1267483

ZY11B
Protein zyg-11 homolog B

2

0

High-throughput

0.328

High

308002

ZWINT
ZW10 interactor

1

0

High-throughput

0.279

Low

454737

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.279

Low

623311

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

High-throughput

0.279

Low

644111

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.279

Low

1157170

IIGP5
Interferon-inducible GTPase 5

1

0

High-throughput

0.279

Low

1267485

CSTL1
Cystatin-like 1

1

0

High-throughput

0.279

Low

1267503

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

330504

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.269

Low

242876

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.249

Low

486591

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

1140666

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024