Protein: EI2BG
Translation initiation factor eIF2B subunit gamma (eIF2B GDP-GTP exchange factor subunit gamma)

Gene: EI2BG, EIF2B3
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9NR50

Gene Ontology (top 5):
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051849

EI2BA
Translation initiation factor eIF2B subunit alpha

4

14

High-throughput

0.900

High

834456

EI2BB
Translation initiation factor eIF2B subunit beta

3

14

High-throughput

0.861

High

339023

EGFR
Epidermal growth factor receptor

4

1

Small-scale

0.672

High

1328923

OPN3
Opsin-3

3

5

High-throughput

0.667

High

1344277

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

1

High-throughput

0.667

High

1022615

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

3

0

High-throughput

0.638

High

599601

SYT1
Synaptotagmin-1

2

3

High-throughput

0.628

High

1240636

UXS1
UDP-glucuronic acid decarboxylase 1

2

1

High-throughput

0.628

High

1344281

FZD10
Frizzled-10

2

1

High-throughput

0.628

High

1025697

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

17

Small-scale

0.619

High

1344279

EI2BD
Translation initiation factor eIF2B subunit delta

1

11

High-throughput

0.618

High

556529

LEUK
Leukosialin

3

1

High-throughput

0.609

High

686822

GP183
G-protein coupled receptor 183

3

6

High-throughput

0.609

High

793158

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

5

High-throughput

0.609

High

1205379

STX12
Syntaxin-12

3

1

High-throughput

0.609

High

1298941

NECT4
Nectin-4

3

2

High-throughput

0.609

High

1304618

P2RX4
P2X purinoceptor 4

3

1

High-throughput

0.609

High

1344282

CAH14
Carbonic anhydrase 14

3

1

High-throughput

0.609

High

228805

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

409803

GLPB
Glycophorin-B

2

1

High-throughput

0.574

High

600681

EPHA1
Ephrin type-A receptor 1

2

1

High-throughput

0.574

High

702301

CD70
CD70 antigen

2

1

High-throughput

0.574

High

1237323

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.574

High

1333284

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.574

High

207275

TNF14
Tumor necrosis factor ligand superfamily member 14

1

1

High-throughput

0.536

High

380338

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.536

High

454762

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.536

High

780789

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

8

High-throughput

0.536

High

873877

IF5
Eukaryotic translation initiation factor 5

1

4

High-throughput

0.536

High

957945

EFNB1
Ephrin-B1

1

2

High-throughput

0.536

High

1166553

BTNL9
Butyrophilin-like protein 9

1

1

High-throughput

0.536

High

1272836

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.536

High

1344283

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

1

High-throughput

0.536

High

282427

STC2
Stanniocalcin-2

1

0

High-throughput

0.518

High

780165

CCNF
Cyclin-F

1

4

High-throughput

0.515

High

308030

ZWINT
ZW10 interactor

1

0

High-throughput

0.513

High

675857

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

894479

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.513

High

1318330

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

238926

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

626802

PTAFR
Platelet-activating factor receptor

1

6

High-throughput

0.489

High

658298

5HT2C
5-hydroxytryptamine receptor 2C

1

1

High-throughput

0.489

High

714930

BTC
Probetacellulin [Cleaved into: Betacellulin

1

2

High-throughput

0.489

High

1031087

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

1067624

P2RY6
P2Y purinoceptor 6

1

6

High-throughput

0.489

High

1078231

CD226
CD226 antigen

1

3

High-throughput

0.489

High

1197989

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1202557

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.489

High

1233668

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1238358

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

1265955

CLC2B
C-type lectin domain family 2 member B

1

2

High-throughput

0.489

High

1303588

SEC62
Translocation protein SEC62

1

1

High-throughput

0.489

High

1328599

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

1344276

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

1

High-throughput

0.489

High

1344280

CC018
Uncharacterized protein C3orf18

1

1

High-throughput

0.489

High

1344284

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.489

High

163332

XPO1
Exportin-1

1

7

High-throughput

0.479

High

246392

SCN2B
Sodium channel subunit beta-2

1

2

High-throughput

0.479

High

347988

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

1042622

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1171867

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1281852

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1284100

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1294037

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1326167

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

High-throughput

0.479

High

1331382

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1332655

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1344273

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1344274

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1344278

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

453640

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

570098

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

793661

DCC
Netrin receptor DCC

1

0

Small-scale

0.458

High

846583

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.458

High

1148806

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1267179

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1344272

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1344275

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1130629

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1302338

CK5P2
CDK5 regulatory subunit-associated protein 2

1

2

High-throughput

0.445

High

553814

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

652347

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

721540

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1033010

PLD1
Phospholipase D1

1

1

High-throughput

0.437

High

1165980

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1188908

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1222107

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

1233340

PNKD
Probable hydrolase PNKD

1

1

High-throughput

0.437

High

1331112

EMRE
Essential MCU regulator, mitochondrial

1

1

High-throughput

0.437

High

99684

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

402516

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

306553

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.282

High

353307

CD4
T-cell surface glycoprotein CD4

1

0

High-throughput

0.279

Low

262593

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

824417

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1231490

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1252042

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

1239869

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.238

Low

1318862

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024