Protein: VPS4A
Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4)

Gene: VPS4A
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9UN37

Gene Ontology (top 5):
GO:0000916 - actomyosin contractile ring contraction
GO:0000922 - spindle pole
GO:0001778 - plasma membrane repair
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342442

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

4

7

Small-scale

0.895

High

260163

VPS4B
Vacuolar protein sorting-associated protein 4B

3

18

High-throughput

0.861

High

1336687

CHM1A
Charged multivesicular body protein 1a

6

20

Small-scale

0.741

High

1295786

ANCHR
Abscission/NoCut checkpoint regulator

5

4

Small-scale

0.718

High

529909

CFTR
Cystic fibrosis transmembrane conductance regulator

4

6

High-throughput

0.691

High

208869

CHM2A
Charged multivesicular body protein 2a

3

20

Small-scale

0.664

High

1357376

VPS4A
Vacuolar protein sorting-associated protein 4A

1

16

High-throughput

0.656

High

1185556

CHM1B
Charged multivesicular body protein 1b

3

20

Small-scale

0.651

High

1316087

CHM4A
Charged multivesicular body protein 4a

3

19

Small-scale

0.645

High

867078

IST1
IST1 homolog

2

8

High-throughput

0.628

High

229057

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

587749

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

17

High-throughput

0.618

High

1330880

Q9H4D1
Protein kinase

1

9

High-throughput

0.618

High

1346686

ARL8B
ADP-ribosylation factor-like protein 8B

2

2

High-throughput

0.611

High

1349476

CHMP5
Charged multivesicular body protein 5

2

20

Small-scale

0.611

High

325552

CLIC3
Chloride intracellular channel protein 3

2

4

High-throughput

0.606

High

1286748

CHM4C
Charged multivesicular body protein 4c

2

19

Small-scale

0.586

High

348231

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.584

High

1357379

CHMP3
Charged multivesicular body protein 3

2

20

Small-scale

0.584

High

883669

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.575

High

168080

NPC1
NPC intracellular cholesterol transporter 1

1

1

Small-scale

0.561

High

1130727

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

7

High-throughput

0.552

High

884405

PCBP4
Poly(rC)-binding protein 4

1

6

High-throughput

0.536

High

1199115

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

4

High-throughput

0.536

High

1233371

SESQ1
Sesquipedalian-1

1

12

High-throughput

0.536

High

1328636

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.536

High

1356842

INTU
Protein inturned

1

1

High-throughput

0.536

High

1347524

BABA1
BRISC and BRCA1-A complex member 1

1

1

High-throughput

0.515

High

1184484

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1273356

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.513

High

1308833

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

1312516

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.513

High

1330555

CHM4B
Charged multivesicular body protein 4b

1

19

High-throughput

0.508

High

175301

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

1357378

CHM2B
Charged multivesicular body protein 2b

1

20

Small-scale

0.501

High

149420

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.479

High

160229

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

3

Small-scale

0.479

High

242911

TRI13
E3 ubiquitin-protein ligase TRIM13

1

5

High-throughput

0.479

High

352308

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

442590

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

531000

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

5

High-throughput

0.479

High

560007

H12
Histone H1.2

1

6

High-throughput

0.479

High

570181

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

591147

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

780319

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

909325

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

928846

RL38
Large ribosomal subunit protein eL38

1

4

High-throughput

0.479

High

985202

DUS2
Dual specificity protein phosphatase 2

1

6

High-throughput

0.479

High

999211

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1036199

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1042836

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1072671

RHEB
GTP-binding protein Rheb

1

4

High-throughput

0.479

High

1088055

DUS6
Dual specificity protein phosphatase 6

1

6

High-throughput

0.479

High

1101373

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1166065

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1172257

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1222122

S15A3
Solute carrier family 15 member 3

1

4

High-throughput

0.479

High

1224163

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

2

Small-scale

0.479

High

1237520

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1267248

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1272905

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

3

High-throughput

0.479

High

1285225

SH3K1
SH3 domain-containing kinase-binding protein 1

1

4

Small-scale

0.479

High

1327148

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

1331622

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

1332771

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1344612

FBX6
F-box only protein 6

1

4

High-throughput

0.479

High

1354856

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1356235

KCND3
Potassium voltage-gated channel subfamily D member 3

1

3

Small-scale

0.479

High

1357377

DUS12
Dual specificity protein phosphatase 12

1

6

High-throughput

0.479

High

319379

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

1152188

LTOR1
Ragulator complex protein LAMTOR1

1

0

Small-scale

0.458

High

1234000

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

497797

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

1044270

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.445

High

1047320

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

1233260

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

1241674

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.445

High

1235467

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

3

Small-scale

0.437

High

240264

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

99698

F5H1C8
Solute carrier family 15 member 3

1

4

High-throughput

0.407

High

1233070

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1347200

TM248
Transmembrane protein 248

1

0

High-throughput

0.279

Low

1288804

MTBP
Mdm2-binding protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024