Protein: HIG1A
HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a)

Gene: HIG1A, HIGD1A
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9Y241

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0032991 - protein-containing complex
GO:0043066 - negative regulation of apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1355907

SPB13
Serpin B13

2

0

High-throughput

0.602

High

498378

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

1

High-throughput

0.571

High

1026249

PAK1
Serine/threonine-protein kinase PAK 1

2

2

High-throughput

0.571

High

1038834

HDAC1
Histone deacetylase 1

2

1

High-throughput

0.571

High

584284

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

385740

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.536

High

348270

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

771481

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

848509

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

1232592

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.513

High

864334

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

1

High-throughput

0.489

High

377813

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

587755

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

4

High-throughput

0.479

High

1139469

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.479

High

1269959

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1316238

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.479

High

1350165

PAK5
Serine/threonine-protein kinase PAK 5

1

2

High-throughput

0.479

High

1354896

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1355738

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.479

High

1377005

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

1

High-throughput

0.479

High

298895

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

320064

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

505692

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

539192

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.458

High

554084

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652637

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721810

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

830306

CASP4
Caspase-4

1

0

High-throughput

0.458

High

918160

H4
Histone H4

1

0

High-throughput

0.458

High

1042866

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1045375

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

1064851

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1077366

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1085550

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.458

High

1086854

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1201774

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1284275

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1319139

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1332787

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1347427

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

1081653

NTRK3
NT-3 growth factor receptor

1

2

High-throughput

0.457

High

602611

COMT
Catechol O-methyltransferase

1

1

High-throughput

0.437

High

968351

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

2

High-throughput

0.437

High

1136362

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1157119

ARMC6
Armadillo repeat-containing protein 6

1

1

High-throughput

0.437

High

1164482

SAMD1
Sterile alpha motif domain-containing protein 1

1

1

High-throughput

0.437

High

1222123

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1259422

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.437

High

1330887

Q9H4D1
Protein kinase

1

3

High-throughput

0.437

High

1335241

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

1377007

PCDBF
Protocadherin beta-15

1

2

High-throughput

0.437

High

1346650

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.426

High

99699

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

883674

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

297207

IPO13
Importin-13

2

0

High-throughput

0.324

High

1175255

TBA1A
Tubulin alpha-1A chain

2

0

High-throughput

0.307

High

925742

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.298

High

1348465

FA13B
Protein FAM13B

2

0

High-throughput

0.298

High

531003

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.279

Low

612127

PROZ
Vitamin K-dependent protein Z

1

0

High-throughput

0.279

Low

813852

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

863853

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.279

Low

1067657

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1295709

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

0

High-throughput

0.279

Low

1315780

STK31
Serine/threonine-protein kinase 31

1

0

High-throughput

0.279

Low

1328640

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1344977

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.279

Low

1345571

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1355105

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.279

Low

147577

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.269

Low

1315405

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

297004

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.249

Low

1119674

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1244190

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.249

Low

1292366

RN185
E3 ubiquitin-protein ligase RNF185

1

0

Small-scale

0.249

Low

1347322

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1377006

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1377008

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024