Protein: CFAB
Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment]

Gene: CFAB, CFB
Organism: Homo sapiens
Interactions: 40
UniProt ID: P00751

Gene Ontology (top 5):
GO:0001848 - complement binding
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005601 - classical-complement-pathway C3/C5 convertase complex
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341566

CO3
Complement C3

3

16

Small-scale

0.845

High

126318

MATN2
Matrilin-2

1

18

High-throughput

0.691

High

198327

KLK10
Kallikrein-10

1

20

High-throughput

0.691

High

341582

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.691

High

341577

PROP
Properdin

1

5

Small-scale

0.647

High

341581

NPC2
NPC intracellular cholesterol transporter 2

2

1

High-throughput

0.628

High

341593

RSPRY
RING finger and SPRY domain-containing protein 1

2

4

High-throughput

0.628

High

341598

DD19B
ATP-dependent RNA helicase DDX19B

2

3

High-throughput

0.611

High

341567

CYTS
Cystatin-S

1

3

High-throughput

0.536

High

341569

ALBU
Albumin

1

3

High-throughput

0.536

High

341573

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.536

High

341576

CALR
Calreticulin

1

8

High-throughput

0.536

High

341578

CCR1
C-C chemokine receptor type 1

1

4

High-throughput

0.536

High

341580

EPHA4
Ephrin type-A receptor 4

1

18

High-throughput

0.536

High

341585

TBB3
Tubulin beta-3 chain

1

20

High-throughput

0.536

High

341586

GRB14
Growth factor receptor-bound protein 14

1

9

High-throughput

0.536

High

341587

TBB8
Tubulin beta-8 chain

1

20

High-throughput

0.536

High

341597

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.536

High

341592

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

341570

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.501

High

341588

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

5

High-throughput

0.489

High

341589

OAF
Out at first protein homolog

1

2

High-throughput

0.489

High

341594

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

5

High-throughput

0.489

High

341596

PHF11
PHD finger protein 11

1

1

High-throughput

0.489

High

341599

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

341600

LAMC3
Laminin subunit gamma-3

1

6

High-throughput

0.481

High

341568

FINC
Fibronectin

1

5

Small-scale

0.479

High

341575

NDKB
Nucleoside diphosphate kinase B

1

4

High-throughput

0.479

High

341583

H11
Histone H1.1

1

1

High-throughput

0.470

High

341571

AMY1B
Alpha-amylase 1B

1

1

High-throughput

0.445

High

341574

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.439

High

260421

PITX3
Pituitary homeobox 3

1

4

Small-scale

0.437

High

341572

H14
Histone H1.4

1

1

High-throughput

0.437

High

341584

FOXO1
Forkhead box protein O1

1

3

High-throughput

0.437

High

341595

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

100162

F6XY72
Histidine protein kinase NDKB

1

4

High-throughput

0.407

High

341590

GDPD1
Lysophospholipase D GDPD1

3

0

High-throughput

0.347

High

341591

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

206303

LTOR5
Ragulator complex protein LAMTOR5

1

0

Small-scale

0.251

Low

341579

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024