Protein: FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

Gene: FIBB, FGB
Organism: Homo sapiens
Interactions: 193
UniProt ID: P02675

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0005102 - signaling receptor binding
GO:0005198 - structural molecule activity
GO:0005201 - extracellular matrix structural constituent
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

198349

KLK10
Kallikrein-10

1

5

High-throughput

0.691

High

361807

ALDH2
Aldehyde dehydrogenase, mitochondrial

3

2

High-throughput

0.667

High

361895

KLK6
Kallikrein-6

1

5

Small-scale

0.647

High

234887

SNX3
Sorting nexin-3

2

1

High-throughput

0.628

High

320484

OXSR1
Serine/threonine-protein kinase OSR1

2

3

High-throughput

0.628

High

361809

H2B1J
Histone H2B type 1-J

2

2

High-throughput

0.628

High

361815

PO2F1
POU domain, class 2, transcription factor 1

2

1

High-throughput

0.628

High

361834

GNL1
Guanine nucleotide-binding protein-like 1

2

1

High-throughput

0.628

High

361846

RHOA
Transforming protein RhoA

2

1

High-throughput

0.628

High

361853

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

3

High-throughput

0.628

High

361855

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

5

High-throughput

0.628

High

361858

RHG01
Rho GTPase-activating protein 1

2

1

High-throughput

0.628

High

361862

PAK1
Serine/threonine-protein kinase PAK 1

2

7

High-throughput

0.628

High

361864

PAK2
Serine/threonine-protein kinase PAK 2

2

7

High-throughput

0.628

High

361885

CCYL1
Cyclin-Y-like protein 1

2

1

High-throughput

0.628

High

361917

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.628

High

361922

SLK
STE20-like serine/threonine-protein kinase

2

5

High-throughput

0.628

High

361942

TES
Testin

2

2

High-throughput

0.628

High

361949

TBC24
TBC1 domain family member 24

2

1

High-throughput

0.628

High

341174

HPT
Haptoglobin

1

9

High-throughput

0.618

High

361821

NDKB
Nucleoside diphosphate kinase B

2

2

High-throughput

0.611

High

361950

DD19B
ATP-dependent RNA helicase DDX19B

2

3

High-throughput

0.611

High

361886

ASCC1
Activating signal cointegrator 1 complex subunit 1

3

2

High-throughput

0.609

High

361806

A4
Amyloid-beta precursor protein

2

5

Small-scale

0.602

High

213787

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

361827

BLVRB
Flavin reductase

2

0

High-throughput

0.602

High

361831

CGL
Cystathionine gamma-lyase

2

0

High-throughput

0.602

High

361837

KPCI
Protein kinase C iota type

2

0

High-throughput

0.602

High

361843

ADK
Adenosine kinase

2

0

High-throughput

0.602

High

361851

VIGLN
Vigilin

2

0

High-throughput

0.602

High

361854

EF1A2
Elongation factor 1-alpha 2

2

0

High-throughput

0.602

High

361859

PPID
Peptidyl-prolyl cis-trans isomerase D

2

0

High-throughput

0.602

High

361867

PMVK
Phosphomevalonate kinase

2

0

High-throughput

0.602

High

361890

CTBL1
Beta-catenin-like protein 1

2

0

High-throughput

0.602

High

361899

SYAP1
Synapse-associated protein 1

2

0

High-throughput

0.602

High

361902

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.602

High

361919

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.602

High

361920

NAA50
N-alpha-acetyltransferase 50

2

0

High-throughput

0.602

High

361947

PSME2
Proteasome activator complex subunit 2

2

0

High-throughput

0.602

High

361956

TLN1
Talin-1

2

0

High-throughput

0.602

High

361824

1433T
14-3-3 protein theta

2

2

High-throughput

0.601

High

361715

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

15

Small-scale

0.575

High

361797

FIBG
Fibrinogen gamma chain

1

15

Small-scale

0.575

High

116757

KIF2A
Kinesin-like protein KIF2A

2

2

High-throughput

0.574

High

361856

RING1
E3 ubiquitin-protein ligase RING1

2

3

High-throughput

0.574

High

361872

MK06
Mitogen-activated protein kinase 6

2

2

High-throughput

0.574

High

361905

SNX27
Sorting nexin-27

2

8

High-throughput

0.574

High

361914

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

2

1

High-throughput

0.574

High

361930

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

1

High-throughput

0.574

High

361951

SNX6
Sorting nexin-6

2

1

High-throughput

0.574

High

233730

NDK8
Putative nucleoside diphosphate kinase

2

2

High-throughput

0.552

High

361875

HS904
Putative heat shock protein HSP 90-alpha A4

2

1

High-throughput

0.552

High

183005

P2RX6
P2X purinoceptor 6

1

2

High-throughput

0.536

High

280334

GLRX3
Glutaredoxin-3

1

2

High-throughput

0.536

High

300700

GLSK
Glutaminase kidney isoform, mitochondrial

1

1

High-throughput

0.536

High

328088

SG1D1
Secretoglobin family 1D member 1

1

2

High-throughput

0.536

High

361813

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

361816

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

361817

LEG3
Galectin-3

1

4

High-throughput

0.536

High

361826

GRAN
Grancalcin

1

2

High-throughput

0.536

High

361828

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

4

High-throughput

0.536

High

361830

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

361833

SPRE
Sepiapterin reductase

1

2

High-throughput

0.536

High

361844

STX17
Syntaxin-17

1

2

High-throughput

0.536

High

361866

SL9A5
Sodium/hydrogen exchanger 5

1

2

High-throughput

0.536

High

361874

FNDC1
Fibronectin type III domain-containing protein 1

1

9

High-throughput

0.536

High

361879

CRDL2
Chordin-like protein 2

1

9

High-throughput

0.536

High

361882

CERS3
Ceramide synthase 3

1

2

High-throughput

0.536

High

361888

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.536

High

361892

DDX1
ATP-dependent RNA helicase DDX1

1

2

High-throughput

0.536

High

361898

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

2

High-throughput

0.536

High

361901

SARAF
Store-operated calcium entry-associated regulatory factor

1

3

High-throughput

0.536

High

361910

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

3

High-throughput

0.536

High

361911

EGFL8
Epidermal growth factor-like protein 8

1

2

High-throughput

0.536

High

361915

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.536

High

361931

XPP1
Xaa-Pro aminopeptidase 1

1

1

High-throughput

0.536

High

361945

DBNL
Drebrin-like protein

1

2

High-throughput

0.536

High

361946

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.536

High

361825

CALR
Calreticulin

1

2

Small-scale

0.534

High

240673

USO1
General vesicular transport factor p115

1

0

High-throughput

0.513

High

294194

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1

0

High-throughput

0.513

High

361811

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.513

High

361819

ICAL
Calpastatin

1

0

High-throughput

0.513

High

361820

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.513

High

361840

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

0

High-throughput

0.513

High

361869

TBCE
Tubulin-specific chaperone E

1

0

High-throughput

0.513

High

361884

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.513

High

361928

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.513

High

361954

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.513

High

361818

ANXA7
Annexin A7

1

2

High-throughput

0.508

High

361865

GRB7
Growth factor receptor-bound protein 7

1

2

High-throughput

0.508

High

361805

VWF
von Willebrand factor

1

6

Small-scale

0.501

High

361814

NID1
Nidogen-1

1

7

Small-scale

0.501

High

361822

FBLN1
Fibulin-1

1

6

Small-scale

0.501

High

217700

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

1

High-throughput

0.489

High

331686

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

High-throughput

0.489

High

361812

ADT3
ADP/ATP translocase 3

1

5

High-throughput

0.489

High

361845

DSCR6
Protein ripply3

1

1

High-throughput

0.489

High

361849

SSBP2
Single-stranded DNA-binding protein 2

1

4

High-throughput

0.489

High

361850

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.489

High

361873

CR021
UPF0711 protein C18orf21

1

2

High-throughput

0.489

High

361876

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.489

High

361880

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.489

High

361881

CIR1
Corepressor interacting with RBPJ 1

1

2

High-throughput

0.489

High

361897

PIGT
GPI transamidase component PIG-T

1

1

High-throughput

0.489

High

361906

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.489

High

361926

CP343
Cytochrome P450 3A43

1

1

High-throughput

0.489

High

361932

MBNL1
Muscleblind-like protein 1

1

2

High-throughput

0.489

High

361944

PHF11
PHD finger protein 11

1

2

High-throughput

0.489

High

361953

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.489

High

361957

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.489

High

361863

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

361848

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.481

High

344139

A1AT
Alpha-1-antitrypsin

1

1

High-throughput

0.479

High

344257

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.479

High

361798

FINC
Fibronectin

1

9

Small-scale

0.479

High

361800

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.479

High

361801

TRFE
Serotransferrin

1

2

High-throughput

0.479

High

361802

HEMO
Hemopexin

1

2

High-throughput

0.479

High

361810

CLUS
Clusterin

1

1

High-throughput

0.479

High

361918

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.479

High

361939

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

8

Small-scale

0.479

High

361921

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.470

High

361835

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.464

High

361893

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

1

High-throughput

0.464

High

298031

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.460

High

336753

CERU
Ceruloplasmin

1

0

High-throughput

0.458

High

361799

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.458

High

361803

STAT
Statherin

1

0

High-throughput

0.458

High

361870

PROL4
Proline-rich protein 4

1

0

High-throughput

0.458

High

361808

F13B
Coagulation factor XIII B chain

1

5

Small-scale

0.445

High

361857

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.445

High

361940

RN181
E3 ubiquitin-protein ligase RNF181

1

1

Small-scale

0.439

High

100368

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

260439

PITX3
Pituitary homeobox 3

1

5

Small-scale

0.437

High

301518

TRI37
E3 ubiquitin-protein ligase TRIM37

1

6

High-throughput

0.437

High

361839

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.437

High

361861

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.437

High

361877

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

2

High-throughput

0.437

High

361887

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

361894

ESR2
Estrogen receptor beta

1

5

High-throughput

0.437

High

361923

ASB7
Ankyrin repeat and SOCS box protein 7

1

3

High-throughput

0.437

High

361927

SP110
Sp110 nuclear body protein

1

3

High-throughput

0.437

High

361937

ASB6
Ankyrin repeat and SOCS box protein 6

1

3

High-throughput

0.437

High

361941

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

361909

THIOM
Thioredoxin, mitochondrial

1

3

High-throughput

0.417

High

100163

F6XY72
Histidine protein kinase NDKB

1

2

High-throughput

0.407

High

361908

TM237
Transmembrane protein 237

3

0

High-throughput

0.347

High

134698

PIR
Pirin

2

0

High-throughput

0.328

High

199031

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

2

0

High-throughput

0.328

High

207699

DENR
Density-regulated protein

2

0

High-throughput

0.328

High

264667

VP26A
Vacuolar protein sorting-associated protein 26A

2

0

High-throughput

0.328

High

275967

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

High-throughput

0.328

High

307307

LETM1
Mitochondrial proton/calcium exchanger protein

2

0

High-throughput

0.328

High

361836

FEN1
Flap endonuclease 1

2

0

High-throughput

0.328

High

361847

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.328

High

361852

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

2

0

High-throughput

0.328

High

361868

SF3A1
Splicing factor 3A subunit 1

2

0

High-throughput

0.328

High

361889

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

2

0

High-throughput

0.328

High

361891

LZIC
Protein LZIC

2

0

High-throughput

0.328

High

361896

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.328

High

361904

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

2

0

High-throughput

0.328

High

361912

VRK1
Serine/threonine-protein kinase VRK1

2

0

High-throughput

0.328

High

361913

PYM1
Partner of Y14 and mago

2

0

High-throughput

0.328

High

361916

ITPA
Inosine triphosphate pyrophosphatase

2

0

High-throughput

0.328

High

361925

ARMT1
Damage-control phosphatase ARMT1

2

0

High-throughput

0.328

High

361929

UBE2T
Ubiquitin-conjugating enzyme E2 T

2

0

High-throughput

0.328

High

361935

RBM12
RNA-binding protein 12

2

0

High-throughput

0.328

High

361936

PNPO
Pyridoxine-5'-phosphate oxidase

2

0

High-throughput

0.328

High

361948

MCTS1
Malignant T-cell-amplified sequence 1

2

0

High-throughput

0.328

High

361952

RRP44
Exosome complex exonuclease RRP44

2

0

High-throughput

0.328

High

361955

SBDS
Ribosome maturation protein SBDS

2

0

High-throughput

0.328

High

167656

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

0

High-throughput

0.279

Low

361823

TCEA1
Transcription elongation factor A protein 1

1

0

High-throughput

0.279

Low

361829

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.279

Low

361832

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.279

Low

361841

PAPOA
Poly(A) polymerase alpha

1

0

High-throughput

0.279

Low

361842

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.279

Low

361860

SCRN1
Secernin-1

1

0

High-throughput

0.279

Low

361883

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

0

High-throughput

0.279

Low

361900

K1143
Uncharacterized protein KIAA1143

1

0

High-throughput

0.279

Low

361903

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

361907

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

361924

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

1

0

High-throughput

0.279

Low

361933

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.279

Low

361934

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.279

Low

361938

HPF1
Histone PARylation factor 1

1

0

High-throughput

0.279

Low

361943

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.279

Low

281098

RL1D1
Ribosomal L1 domain-containing protein 1

1

0

High-throughput

0.269

Low

361804

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

361871

SMN
Survival motor neuron protein

1

0

High-throughput

0.265

Low

361838

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

361878

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024