Protein: S27A2
Long-chain fatty acid transport protein 2 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Phytanate--CoA ligase) (EC 6.2.1.24) (Solute carrier family 27 member 2) (THCA-CoA ligase) (EC 6.2.1.7) (Very long-chain acyl-CoA synthetase) (VLACS) (VLCS) (EC 6.2.1.-) (Very long-chain-fatty-acid-CoA ligase)

Gene: S27A2, SLC27A2
Organism: Homo sapiens
Interactions: 108
UniProt ID: O14975

Gene Ontology (top 5):
GO:0001561 - fatty acid alpha-oxidation
GO:0001676 - long-chain fatty acid metabolic process
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005324 - long-chain fatty acid transmembrane transporter activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

161551

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

3

1

High-throughput

0.667

High

161506

FAS
Fatty acid synthase

1

0

High-throughput

0.656

High

161495

GLU2B
Glucosidase 2 subunit beta

3

0

High-throughput

0.638

High

161554

PCAT1
Lysophosphatidylcholine acyltransferase 1

3

0

High-throughput

0.638

High

161566

HAUS7
HAUS augmin-like complex subunit 7

3

0

High-throughput

0.638

High

161578

PLPL3
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

3

0

High-throughput

0.634

High

161486

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

1

High-throughput

0.628

High

161535

ARMC6
Armadillo repeat-containing protein 6

2

2

High-throughput

0.628

High

161574

UN45A
Protein unc-45 homolog A

2

1

High-throughput

0.628

High

161511

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.611

High

161512

VA0D1
V-type proton ATPase subunit d 1

2

1

High-throughput

0.611

High

161536

S39A4
Zinc transporter ZIP4

2

2

High-throughput

0.611

High

161483

GSDME
Gasdermin-E

2

0

High-throughput

0.602

High

161507

EI2BB
Translation initiation factor eIF2B subunit beta

2

0

High-throughput

0.602

High

161546

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.602

High

161559

B2CL2
Bcl-2-like protein 2

2

0

High-throughput

0.602

High

161498

ASM
Sphingomyelin phosphodiesterase

2

0

High-throughput

0.585

High

161560

HPS1
BLOC-3 complex member HPS1

2

0

High-throughput

0.585

High

161484

RNBP6
Ran-binding protein 6

2

3

High-throughput

0.574

High

127131

IPO5
Importin-5

1

3

High-throughput

0.536

High

161481

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

161485

RAMP3
Receptor activity-modifying protein 3

1

3

High-throughput

0.536

High

161488

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

161490

ACHA
Acetylcholine receptor subunit alpha

1

3

High-throughput

0.536

High

161491

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

1

High-throughput

0.536

High

161503

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.536

High

161509

IMA1
Importin subunit alpha-1

1

2

High-throughput

0.536

High

161520

VAC14
Protein VAC14 homolog

1

4

High-throughput

0.536

High

161524

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

4

High-throughput

0.536

High

161525

IMB1
Importin subunit beta-1

1

2

High-throughput

0.536

High

161527

P2RY6
P2Y purinoceptor 6

1

6

High-throughput

0.536

High

161529

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

161531

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

161542

RETR3
Reticulophagy regulator 3

1

1

High-throughput

0.536

High

161544

SFPA2
Pulmonary surfactant-associated protein A2

1

1

High-throughput

0.536

High

161553

RETR2
Reticulophagy regulator 2

1

1

High-throughput

0.536

High

161561

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

161563

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.536

High

161572

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.536

High

161573

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

161582

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.536

High

126728

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

161496

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

161499

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.513

High

161517

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

161534

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.513

High

161537

MIGA2
Mitoguardin 2

1

0

High-throughput

0.513

High

161538

DYM
Dymeclin

1

0

High-throughput

0.513

High

161539

OTOAN
Otoancorin

1

0

High-throughput

0.513

High

161543

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

1

0

High-throughput

0.513

High

161549

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.513

High

161552

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.513

High

161556

RAB2B
Ras-related protein Rab-2B

1

0

High-throughput

0.513

High

161568

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.513

High

161493

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

161500

1433T
14-3-3 protein theta

1

1

High-throughput

0.501

High

161565

XPO6
Exportin-6

1

0

High-throughput

0.493

High

161487

SG2A1
Mammaglobin-B

1

1

High-throughput

0.489

High

161521

SG2A2
Mammaglobin-A

1

1

High-throughput

0.489

High

161583

5MP1
eIF5-mimic protein 1

1

1

High-throughput

0.489

High

161480

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

161492

RHOC
Rho-related GTP-binding protein RhoC

1

1

High-throughput

0.479

High

161497

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

161504

BASI
Basigin

1

1

High-throughput

0.479

High

161505

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

161510

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

161514

TSN5
Tetraspanin-5

1

6

High-throughput

0.479

High

161515

H4
Histone H4

1

1

High-throughput

0.479

High

161516

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

161522

CUL3
Cullin-3

1

4

High-throughput

0.479

High

161541

PAQR2
Adiponectin receptor protein 2

1

1

Small-scale

0.479

High

161550

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

161555

RN139
E3 ubiquitin-protein ligase RNF139

1

2

High-throughput

0.479

High

161557

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

6

High-throughput

0.479

High

161569

DERL1
Derlin-1

1

1

High-throughput

0.479

High

161575

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

161581

RNF11
RING finger protein 11

1

3

Small-scale

0.479

High

161502

ABCD1
ATP-binding cassette sub-family D member 1

1

0

Small-scale

0.460

High

155200

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

161518

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

161526

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

161489

IGHM
Immunoglobulin heavy constant mu

1

1

High-throughput

0.445

High

161501

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

161523

CUL4A
Cullin-4A

1

4

High-throughput

0.437

High

161528

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.437

High

161545

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

161579

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

161508

PEX5
Peroxisomal targeting signal 1 receptor

1

2

Small-scale

0.408

High

99514

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

161547

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

161567

RM34
Large ribosomal subunit protein bL34m

2

0

High-throughput

0.328

High

161570

CNPD1
Protein CNPPD1

2

0

High-throughput

0.328

High

161519

CTSL2
CTD small phosphatase-like protein 2

1

0

High-throughput

0.279

Low

161532

LRC73
Leucine-rich repeat-containing protein 73

1

0

High-throughput

0.279

Low

161540

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

161558

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

161562

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

161564

TM169
Transmembrane protein 169

1

0

High-throughput

0.279

Low

161571

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

161576

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

161577

ROP1A
Ropporin-1A

1

0

High-throughput

0.279

Low

161482

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

161513

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

161548

EID3
EP300-interacting inhibitor of differentiation 3

1

0

High-throughput

0.249

Low

161580

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.249

Low

161494

PNM6A
Paraneoplastic antigen-like protein 6A

1

0

High-throughput

0.232

Low

161530

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.232

Low

161533

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024