Protein: TXD12
Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19)

Gene: TXD12, TXNDC12
Organism: Homo sapiens
Interactions: 75
UniProt ID: O95881

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0015035 - protein-disulfide reductase activity
GO:0019153 - protein-disulfide reductase (glutathione) activity
GO:1902236 - negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

327214

UBQL1
Ubiquilin-1

2

6

High-throughput

0.628

High

327201

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

3

7

High-throughput

0.616

High

327168

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

2

1

High-throughput

0.606

High

327219

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

2

High-throughput

0.606

High

327164

TBG1
Tubulin gamma-1 chain

2

7

High-throughput

0.574

High

327186

MZT2B
Mitotic-spindle organizing protein 2B

2

1

High-throughput

0.574

High

327187

MZT2A
Mitotic-spindle organizing protein 2A

2

1

High-throughput

0.574

High

327200

GCP3
Gamma-tubulin complex component 3

2

4

High-throughput

0.574

High

327204

GCP6
Gamma-tubulin complex component 6

2

4

High-throughput

0.574

High

327205

GCP5
Gamma-tubulin complex component 5

2

4

High-throughput

0.574

High

327207

GCP2
Gamma-tubulin complex component 2

2

4

High-throughput

0.574

High

327212

GCP4
Gamma-tubulin complex component 4

2

4

High-throughput

0.574

High

327218

NDK7
Nucleoside diphosphate kinase homolog 7

2

1

High-throughput

0.574

High

327198

REQU
Zinc finger protein ubi-d4

2

3

High-throughput

0.553

High

327213

UBQL2
Ubiquilin-2

2

6

High-throughput

0.553

High

327174

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

213429

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

7

High-throughput

0.523

High

327157

HCK
Tyrosine-protein kinase HCK

2

1

High-throughput

0.521

High

327166

PEBP1
Phosphatidylethanolamine-binding protein 1

2

1

High-throughput

0.521

High

327178

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.521

High

327192

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

4

High-throughput

0.521

High

327195

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.521

High

327199

ARHG1
Rho guanine nucleotide exchange factor 1

2

2

High-throughput

0.521

High

327193

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.494

High

327162

H2AX
Histone H2AX

1

2

High-throughput

0.489

High

327220

SAR1B
Small COPII coat GTPase SAR1B

1

8

High-throughput

0.489

High

204889

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

327160

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

298023

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

327202

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

327152

ESR1
Estrogen receptor

1

1

High-throughput

0.437

High

327154

NPM
Nucleophosmin

1

1

High-throughput

0.437

High

327155

CATL1
Procathepsin L

1

1

High-throughput

0.437

High

327156

CATB
Cathepsin B

1

2

High-throughput

0.437

High

327158

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.437

High

327165

CATS
Cathepsin S

1

1

High-throughput

0.437

High

327171

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.437

High

327172

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

327175

PWP1
Periodic tryptophan protein 1 homolog

1

2

High-throughput

0.437

High

327176

CUL3
Cullin-3

1

1

High-throughput

0.437

High

327177

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.437

High

327179

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.437

High

327181

SMU1
WD40 repeat-containing protein SMU1

1

3

High-throughput

0.437

High

327182

EPHAA
Ephrin type-A receptor 10

1

1

High-throughput

0.437

High

327183

DCA10
DDB1- and CUL4-associated factor 10

1

2

High-throughput

0.437

High

327185

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

327188

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

327190

WDR53
WD repeat-containing protein 53

1

2

High-throughput

0.437

High

327194

WDTC1
WD and tetratricopeptide repeats protein 1

1

6

High-throughput

0.437

High

327196

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.437

High

327208

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

327209

DCA13
DDB1- and CUL4-associated factor 13

1

2

High-throughput

0.437

High

327211

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

327153

PRIO
Major prion protein

1

0

High-throughput

0.426

High

327159

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.407

High

307155

KLHL2
Kelch-like protein 2

3

0

High-throughput

0.348

High

327206

TM2D3
TM2 domain-containing protein 3

2

0

High-throughput

0.328

High

327161

BRAF
Serine/threonine-protein kinase B-raf

2

0

High-throughput

0.298

High

327203

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.269

Low

327215

GBRT
Gamma-aminobutyric acid receptor subunit theta

1

0

High-throughput

0.269

Low

100354

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

327151

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

327163

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

327167

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

327170

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

327173

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

327180

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.249

Low

327184

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

327189

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

327191

MTMRD
Myotubularin-related protein 13

1

0

High-throughput

0.249

Low

327197

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

327210

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

327216

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.249

Low

327217

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

327169

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024