Protein: PTPRZ
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)

Gene: PTPRZ, PTPRZ1
Organism: Homo sapiens
Interactions: 35
UniProt ID: P23471

Gene Ontology (top 5):
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005178 - integrin binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

617163

CNTN1
Contactin-1

2

12

Small-scale

0.819

High

396567

ITB3
Integrin beta-3

2

10

Small-scale

0.754

High

617172

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.724

High

617156

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

2

19

Small-scale

0.701

High

412018

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.680

High

572282

LEG3
Galectin-3

3

20

High-throughput

0.667

High

383613

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

411598

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.647

High

489902

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

16

Small-scale

0.647

High

617158

CSK
Tyrosine-protein kinase CSK

1

20

High-throughput

0.647

High

617171

TENR
Tenascin-R

1

20

Small-scale

0.647

High

617167

CYTSA
Cytospin-A

1

2

High-throughput

0.618

High

352494

TNFA
Tumor necrosis factor

1

1

High-throughput

0.618

High

617173

GIT1
ARF GTPase-activating protein GIT1

1

3

Small-scale

0.618

High

449194

LEG1
Galectin-1

2

20

Small-scale

0.611

High

419158

ITAV
Integrin alpha-V

2

8

Small-scale

0.584

High

617169

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.553

High

449541

HMGB1
High mobility group protein B1

1

1

Small-scale

0.501

High

600943

MK
Midkine

1

4

Small-scale

0.501

High

617160

WASP
Actin nucleation-promoting factor WAS

1

8

High-throughput

0.501

High

617161

PAXI
Paxillin

1

10

High-throughput

0.501

High

617168

IL34
Interleukin-34

1

1

Small-scale

0.501

High

617162

ACTA
Actin, aortic smooth muscle

1

2

High-throughput

0.489

High

549555

VEGFA
Vascular endothelial growth factor A, long form

1

2

Small-scale

0.479

High

597361

PTN
Pleiotrophin

1

4

Small-scale

0.479

High

617157

CTNB1
Catenin beta-1

1

20

Small-scale

0.479

High

582068

NUCL
Nucleolin

1

0

Small-scale

0.458

High

617165

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

Small-scale

0.458

High

617159

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.445

High

377932

PRIO
Major prion protein

1

0

High-throughput

0.426

High

617170

SELH
Selenoprotein H

1

0

High-throughput

0.279

Low

617166

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

Small-scale

0.261

Low

100487

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

617164

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024