Protein: MED4
Mediator of RNA polymerase II transcription subunit 4

Gene: MED4
Organism: Arabidopsis thaliana
Interactions: 93
UniProt ID: Q9LZ00

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1341761

MED9
Mediator of RNA polymerase II transcription subunit 9

2

0

Small-scale

0.579

High

103320

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.560

High

1354416

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

Small-scale

0.560

High

1425517

MD10A
Mediator of RNA polymerase II transcription subunit 10a

1

0

Small-scale

0.438

High

1443904

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

Small-scale

0.438

High

101446

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

Small-scale

0.426

High

1082238

Q0WSC4
Signal recognition particle receptor subunit beta

1

1

Small-scale

0.417

High

4008

A0A178USJ2
ACHT2

1

0

Small-scale

0.238

Low

45890

A0A1P8APR2
Plastocyanin

1

0

Small-scale

0.238

Low

86152

B9DG54
AT3G45050 protein

1

0

Small-scale

0.238

Low

86229

B9DHC9
AT1G53800 protein

1

0

Small-scale

0.238

Low

99946

F4I0P9
DNA ligase

1

0

Small-scale

0.238

Low

101508

F4J0E6
Transmembrane protein, putative

1

0

Small-scale

0.238

Low

101800

F4J934
SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein

1

0

Small-scale

0.238

Low

102937

F4JWU1
SPOC domain / Transcription elongation factor S-II protein

1

0

Small-scale

0.238

Low

102949

F4JXH7
RNA binding

1

0

Small-scale

0.238

Low

102989

KN7H
Kinesin-like protein KIN-7H

1

0

Small-scale

0.238

Low

103593

F4K735
Quinoprotein amine dehydrogenase, beta chain-like RIC1-like guanyl-nucleotide exchange factor

1

0

Small-scale

0.238

Low

103631

F4K8Y6
Exocyst subunit Exo70 family protein

1

0

Small-scale

0.238

Low

146351

CLC2
Clathrin light chain 2

1

0

Small-scale

0.238

Low

199146

UNE12
Transcription factor UNE12

1

0

Small-scale

0.238

Low

200139

GLYC4
Serine hydroxymethyltransferase 4

1

0

Small-scale

0.238

Low

200663

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.238

Low

235882

PDRP1
Pyruvate, phosphate dikinase regulatory protein 1, chloroplastic

1

0

Small-scale

0.238

Low

307491

WOX13
WUSCHEL-related homeobox 13

1

0

Small-scale

0.238

Low

308169

O82329
MAR-binding filament-like protein

1

0

Small-scale

0.238

Low

680222

ENO2
Bifunctional enolase 2/transcriptional activator

1

0

Small-scale

0.238

Low

701382

RAA5C
Ras-related protein RABA5c

1

0

Small-scale

0.238

Low

718218

TOP1A
DNA topoisomerase 1 alpha

1

0

Small-scale

0.238

Low

829619

ARF3
ADP-ribosylation factor 3

1

0

Small-scale

0.238

Low

1020297

PROD1
Proline dehydrogenase 1, mitochondrial

1

0

Small-scale

0.238

Low

1020431

RR5
Small ribosomal subunit protein uS5c

1

0

Small-scale

0.238

Low

1028006

SUS2
Sucrose synthase 2

1

0

Small-scale

0.238

Low

1168657

Q1G3N4
TPRXL

1

0

Small-scale

0.238

Low

1177776

Q2HIR7
Acclimation of photosynthesis to environment

1

0

Small-scale

0.238

Low

1194043

XB35
Putative E3 ubiquitin-protein ligase XBAT35

1

0

Small-scale

0.238

Low

1231338

Q6DBH4
5'-deoxynucleotidase

1

0

Small-scale

0.238

Low

1236850

Q6NNJ2
At5g01790

1

0

Small-scale

0.238

Low

1283543

Q84J43
Binding protein

1

0

Small-scale

0.238

Low

1283635

Q84JF2
Class I peptide chain release factor

1

0

Small-scale

0.238

Low

1299131

Q8GW91
At3g02820

1

0

Small-scale

0.238

Low

1299138

Q8GWB4
At2g43110

1

0

Small-scale

0.238

Low

1318270

RPS9M
Small ribosomal subunit protein uS9m

1

0

Small-scale

0.238

Low

1342827

SEC5A
Exocyst complex component SEC5A

1

0

Small-scale

0.238

Low

1342959

TIG
Trigger factor-like protein TIG, Chloroplastic

1

0

Small-scale

0.238

Low

1342968

SPK1
Guanine nucleotide exchange factor SPIKE 1

1

0

Small-scale

0.238

Low

1354159

AML5
Protein MEI2-like 5

1

0

Small-scale

0.238

Low

1355089

RT11
Small ribosomal subunit protein uS11m

1

0

Small-scale

0.238

Low

1355452

HC173
Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 173, chloroplastic

1

0

Small-scale

0.238

Low

1375136

Q945P2
AT5g49210/K21P3_8

1

0

Small-scale

0.238

Low

1376801

SYP72
Syntaxin-72

1

0

Small-scale

0.238

Low

1379540

ATPO
ATP synthase subunit O, mitochondrial

1

0

Small-scale

0.238

Low

1421738

14312
14-3-3-like protein GF14 iota

1

0

Small-scale

0.238

Low

1421920

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.238

Low

1423293

Q9CA21
Pleckstrin homology

1

0

Small-scale

0.238

Low

1423512

HIR2
Hypersensitive-induced response protein 2

1

0

Small-scale

0.238

Low

1425049

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

Small-scale

0.238

Low

1426072

Q9FKM4
At5g57460

1

0

Small-scale

0.238

Low

1426275

NC100
NAC domain-containing protein 100

1

0

Small-scale

0.238

Low

1426428

Q9FM11
Phosphoglycerate mutase family protein

1

0

Small-scale

0.238

Low

1426604

TCLOT
Thioredoxin-like protein Clot

1

0

Small-scale

0.238

Low

1426818

NUD27
Nudix hydrolase 27, chloroplastic

1

0

Small-scale

0.238

Low

1426947

GUFP
Translation factor GUF1 homolog, chloroplastic

1

0

Small-scale

0.238

Low

1426957

DEXHE
DExH-box ATP-dependent RNA helicase DExH14

1

0

Small-scale

0.238

Low

1427212

BZIP9
Basic leucine zipper 9

1

0

Small-scale

0.238

Low

1427323

6PGD2
6-phosphogluconate dehydrogenase, decarboxylating 2

1

0

Small-scale

0.238

Low

1427596

Q9FYR1
Gb|AAD20160.1

1

0

Small-scale

0.238

Low

1427631

AGP31
Non-classical arabinogalactan protein 31

1

0

Small-scale

0.238

Low

1441336

RRP32
Small ribosomal subunit protein cS23y

1

0

Small-scale

0.238

Low

1441638

Q9LJF2
L-ascorbate oxidase pectinesterase-like protein pollen-specific protein-like

1

0

Small-scale

0.238

Low

1441843

LECT5
Lectin-like protein At3g16530

1

0

Small-scale

0.238

Low

1442065

Q9LMQ3
Small ribosomal subunit protein uS15c

1

0

Small-scale

0.238

Low

1442528

Q9LPU1
Secondary thiamine-phosphate synthase enzyme

1

0

Small-scale

0.238

Low

1442821

Q9LS61
At3g18295

1

0

Small-scale

0.238

Low

1442831

PUB29
U-box domain-containing protein 29

1

0

Small-scale

0.238

Low

1443281

Q9LUV9
Sec14p-like phosphatidylinositol transfer family protein

1

0

Small-scale

0.238

Low

1443872

FRI3
Ferritin-3, chloroplastic

1

0

Small-scale

0.238

Low

1443905

SIR
Assimilatory sulfite reductase

1

0

Small-scale

0.238

Low

1443906

RID3
Protein ROOT INITIATION DEFECTIVE 3

1

0

Small-scale

0.238

Low

1443907

Q9SGN8
F3M18.16

1

0

Small-scale

0.238

Low

1443908

Q9SIE6
Hydroxyproline-rich glycoprotein family protein

1

0

Small-scale

0.238

Low

1443909

HIP5
Heavy metal-associated isoprenylated plant protein 5

1

0

Small-scale

0.238

Low

1443910

VHAA2
V-type proton ATPase subunit a2

1

0

Small-scale

0.238

Low

1443911

Q9SKA8
Elongation factor 1-delta, putative

1

0

Small-scale

0.238

Low

1443912

SLY1
SEC1 family transport protein SLY1

1

0

Small-scale

0.238

Low

1443913

TRP2
Telomere repeat-binding protein 2

1

0

Small-scale

0.238

Low

1443914

ANXD1
Annexin D1

1

0

Small-scale

0.238

Low

1443915

PETS
Polyprotein of EF-Ts, chloroplastic

1

0

Small-scale

0.238

Low

1443916

SYLM
Leucine--tRNA ligase, chloroplastic/mitochondrial

1

0

Small-scale

0.238

Low

1443917

Q9ZUM1
At2g02170/F5O4.6

1

0

Small-scale

0.238

Low

1443918

PP172
Pentatricopeptide repeat-containing protein At2g27610

1

0

Small-scale

0.238

Low

1443919

Q9ZVP0
At1g05060

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025