Protein: 3MG
DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)

Gene: 3MG, MPG
Organism: Homo sapiens
Interactions: 117
UniProt ID: P29372

Gene Ontology (top 5):
GO:0003684 - damaged DNA binding
GO:0003905 - alkylbase DNA N-glycosylase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006284 - base-excision repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

369043

ESR1
Estrogen receptor

3

1

Small-scale

0.660

High

666415

DHB14
17-beta-hydroxysteroid dehydrogenase 14

3

0

High-throughput

0.654

High

305733

ELP1
Elongator complex protein 1

3

0

High-throughput

0.638

High

666402

ELP2
Elongator complex protein 2

3

0

High-throughput

0.638

High

666423

ELP3
Elongator complex protein 3

3

0

High-throughput

0.638

High

666361

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.586

High

666365

MLH1
DNA mismatch repair protein Mlh1

2

0

High-throughput

0.580

High

666367

CRK
Adapter molecule crk

2

0

High-throughput

0.569

High

552014

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

650440

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

666362

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

666373

CAZA1
F-actin-capping protein subunit alpha-1

2

0

Small-scale

0.559

High

666391

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.559

High

666410

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

377948

PRIO
Major prion protein

1

0

Small-scale

0.537

High

666427

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.518

High

386159

P53
Cellular tumor antigen p53

1

0

High-throughput

0.513

High

417964

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

649325

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

666408

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.513

High

666374

RD23A
UV excision repair protein RAD23 homolog A

1

0

Small-scale

0.504

High

499552

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

597476

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.493

High

666366

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.493

High

666409

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.493

High

394172

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

666438

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

637635

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.479

High

666400

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

1

Small-scale

0.479

High

666406

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

666411

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

1

Small-scale

0.479

High

666413

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

666414

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

1

Small-scale

0.479

High

199673

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

Small-scale

0.458

High

205080

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

214861

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

254552

CLAP2
CLIP-associating protein 2

1

0

Small-scale

0.458

High

302945

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

346011

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

378435

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

413836

GELS
Gelsolin

1

0

Small-scale

0.458

High

535799

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

537812

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.458

High

574251

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

579663

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

596251

FILA
Filaggrin

1

0

Small-scale

0.458

High

637332

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

666363

RFC4
Replication factor C subunit 4

1

0

Small-scale

0.458

High

666364

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.458

High

666369

FXR2
RNA-binding protein FXR2

1

0

Small-scale

0.458

High

666370

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

666371

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.458

High

666372

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.458

High

666376

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

666377

H4
Histone H4

1

0

High-throughput

0.458

High

666378

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

666379

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.458

High

666380

H31
Histone H3.1

1

0

High-throughput

0.458

High

666381

SET
Protein SET

1

0

High-throughput

0.458

High

666382

CSTF1
Cleavage stimulation factor subunit 1

1

0

Small-scale

0.458

High

666383

EXOS9
Exosome complex component RRP45

1

0

Small-scale

0.458

High

666384

PRDX1
Peroxiredoxin-1

1

0

Small-scale

0.458

High

666385

SRSF1
Serine/arginine-rich splicing factor 1

1

0

Small-scale

0.458

High

666386

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.458

High

666389

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

666390

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

Small-scale

0.458

High

666392

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

666396

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

Small-scale

0.458

High

666397

MIDN
Midnolin

1

0

High-throughput

0.458

High

666399

OBSCN
Obscurin

1

0

Small-scale

0.458

High

666404

LARP4
La-related protein 4

1

0

Small-scale

0.458

High

666407

FUBP2
Far upstream element-binding protein 2

1

0

Small-scale

0.458

High

666412

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

Small-scale

0.458

High

666418

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

666419

RGAP1
Rac GTPase-activating protein 1

1

0

Small-scale

0.458

High

666421

DHX33
ATP-dependent RNA helicase DHX33

1

0

Small-scale

0.458

High

666422

MOB1A
MOB kinase activator 1A

1

0

High-throughput

0.458

High

666424

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

666429

TFP11
Tuftelin-interacting protein 11

1

0

Small-scale

0.458

High

666430

MO4L1
Mortality factor 4-like protein 1

1

0

Small-scale

0.458

High

666431

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

666434

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.458

High

666435

KDM2A
Lysine-specific demethylase 2A

1

0

Small-scale

0.458

High

666436

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

Small-scale

0.458

High

666439

NOC2L
Nucleolar complex protein 2 homolog

1

0

Small-scale

0.458

High

666388

NOG2
Nucleolar GTP-binding protein 2

1

1

Small-scale

0.437

High

666416

GNL3
Guanine nucleotide-binding protein-like 3

1

1

Small-scale

0.437

High

666432

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

401476

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

666425

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.426

High

666426

KBTB4
Kelch repeat and BTB domain-containing protein 4

3

0

High-throughput

0.347

High

100516

APRIO
Alternative prion protein

1

0

Small-scale

0.292

High

171939

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.282

High

666420

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.279

Low

337205

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.269

Low

612825

FBLN1
Fibulin-1

1

0

High-throughput

0.269

Low

123511

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.249

Low

391562

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.249

Low

533411

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

612094

LSHR
Lutropin-choriogonadotropic hormone receptor

1

0

Small-scale

0.249

Low

623891

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

666368

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.249

Low

666375

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

666387

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.249

Low

666393

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.249

Low

666394

CDSN
Corneodesmosin

1

0

Small-scale

0.249

Low

666395

CYTM
Cystatin-M

1

0

Small-scale

0.249

Low

666398

KPRP
Keratinocyte proline-rich protein

1

0

Small-scale

0.249

Low

666401

PR38B
Pre-mRNA-splicing factor 38B

1

0

Small-scale

0.249

Low

666403

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

666405

SPA12
Serpin A12

1

0

Small-scale

0.249

Low

666417

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low

666428

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

666433

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

0

High-throughput

0.249

Low

666437

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.249

Low

239799

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024