Protein: PURA2
Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)

Gene: PURA2, ADSS2
Organism: Homo sapiens
Interactions: 81
UniProt ID: P30520

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002376 - immune system process
GO:0004019 - adenylosuccinate synthase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674333

PURA1
Adenylosuccinate synthetase isozyme 1

3

3

High-throughput

0.855

High

674334

SMYD1
Histone-lysine N-methyltransferase SMYD1

4

0

High-throughput

0.679

High

674299

LEG7
Galectin-7

2

0

High-throughput

0.585

High

226624

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

674304

TERA
Transitional endoplasmic reticulum ATPase

2

0

High-throughput

0.559

High

271852

SPB7
Serpin B7

1

0

High-throughput

0.513

High

674323

CUL3
Cullin-3

1

0

High-throughput

0.513

High

674330

SBSN
Suprabasin

1

0

High-throughput

0.513

High

674337

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

674340

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

674344

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

354318

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

382322

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.479

High

499562

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

517083

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

646658

1433T
14-3-3 protein theta

1

1

High-throughput

0.479

High

674296

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.479

High

674298

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

674316

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

674331

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

674332

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

1

High-throughput

0.479

High

243304

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

254049

WDR1
WD repeat-containing protein 1

1

0

High-throughput

0.458

High

344943

CYTN
Cystatin-SN

1

0

Small-scale

0.458

High

346030

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

351278

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

385844

CPNS1
Calpain small subunit 1

1

0

High-throughput

0.458

High

388254

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.458

High

393060

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

470279

H2A1
Histone H2A type 1

1

0

High-throughput

0.458

High

503516

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

527954

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.458

High

531046

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

577813

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.458

High

616135

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

670810

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

674293

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

674295

TALDO
Transaldolase

1

0

High-throughput

0.458

High

674297

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

674300

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.458

High

674302

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.458

High

674303

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.458

High

674305

DEST
Destrin

1

0

High-throughput

0.458

High

674306

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

674307

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.458

High

674308

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

674309

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.458

High

674310

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

674311

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

674312

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

674313

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

674314

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

674315

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

674317

H31
Histone H3.1

1

0

High-throughput

0.458

High

674319

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.458

High

674321

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

674322

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.458

High

674324

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

674325

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

674326

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

674328

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

674335

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

674341

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

0

High-throughput

0.458

High

674342

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.458

High

674343

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.458

High

552028

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

674320

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

120844

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

496394

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

674329

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

674339

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

674336

NPB
Neuropeptide B

2

0

High-throughput

0.328

High

674301

KLK7
Kallikrein-7

1

0

High-throughput

0.279

Low

674327

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

674338

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

100525

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

243994

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

329414

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

650455

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

674294

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

674318

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024