Protein: DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)

Gene: DUT
Organism: Homo sapiens
Interactions: 66
UniProt ID: P33316

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0004170 - dUTP diphosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704271

NUD18
8-oxo-dGDP phosphatase NUDT18

2

0

High-throughput

0.613

High

704257

RHOB
Rho-related GTP-binding protein RhoB

2

1

Small-scale

0.576

High

346063

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

704289

RHG35
Rho GTPase-activating protein 35

2

0

High-throughput

0.547

High

704293

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.518

High

704263

CUL3
Cullin-3

1

0

High-throughput

0.513

High

226656

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.493

High

704249

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.493

High

704295

TLN1
Talin-1

1

0

High-throughput

0.493

High

369077

ESR1
Estrogen receptor

1

2

High-throughput

0.481

High

510004

ERR1
Steroid hormone receptor ERR1

1

2

High-throughput

0.481

High

704256

ERR3
Estrogen-related receptor gamma

1

2

High-throughput

0.481

High

436175

RHOC
Rho-related GTP-binding protein RhoC

1

1

High-throughput

0.479

High

704262

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

704273

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

704276

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

704288

BIRC6
Baculoviral IAP repeat-containing protein 6

1

1

Small-scale

0.479

High

278399

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.460

High

244010

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

294439

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

302957

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

499568

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

704250

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

704252

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

704254

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

704255

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

704264

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

704265

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

704266

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

704267

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

704269

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

704274

MAVS
Mitochondrial antiviral-signaling protein

1

0

Small-scale

0.458

High

704275

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

704277

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

704278

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

704279

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

704286

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

704290

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

704291

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

660407

GRN
Progranulin

1

1

High-throughput

0.445

High

704251

RND2
Rho-related GTP-binding protein RhoN

1

2

High-throughput

0.437

High

704260

RON
Macrophage-stimulating protein receptor

1

1

High-throughput

0.437

High

704282

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

256944

KDM4A
Lysine-specific demethylase 4A

1

0

Small-scale

0.426

High

377963

PRIO
Major prion protein

1

0

High-throughput

0.426

High

704258

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.426

High

305991

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.407

High

704253

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.407

High

704283

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.407

High

704261

SOS2
Son of sevenless homolog 2

2

0

High-throughput

0.298

High

704268

RHGBB
Inactive Rho GTPase-activating protein 11B

2

0

High-throughput

0.298

High

704285

PKHF2
Pleckstrin homology domain-containing family F member 2

1

0

High-throughput

0.292

High

100541

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

321875

RIGI
Antiviral innate immune response receptor RIG-I

1

0

Small-scale

0.249

Low

351725

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

600518

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.249

Low

704270

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

704280

RHOV
Rho-related GTP-binding protein RhoV

1

0

High-throughput

0.249

Low

704281

RHBT2
Rho-related BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

704284

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

704287

NGB
Neuroglobin

1

0

High-throughput

0.249

Low

704292

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.249

Low

704294

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

264277

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.232

Low

704259

TAGL
Transgelin

1

0

High-throughput

0.232

Low

704272

NEK10
Serine/threonine-protein kinase Nek10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024