Protein: SPB6
Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)

Gene: SPB6, SERPINB6
Organism: Homo sapiens
Interactions: 35
UniProt ID: P35237

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341545

TPA
Tissue-type plasminogen activator

2

20

High-throughput

0.811

High

719371

SPB8
Serpin B8

2

6

High-throughput

0.811

High

719387

KLK13
Kallikrein-13

2

20

High-throughput

0.789

High

589593

KLK2
Kallikrein-2

2

20

Small-scale

0.768

High

341138

THRB
Prothrombin

1

20

Small-scale

0.647

High

719380

TM11A
Transmembrane protease serine 11A

1

13

High-throughput

0.618

High

226669

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

270584

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.541

High

719374

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

7

High-throughput

0.536

High

319736

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.479

High

346077

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

384377

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

719369

CRK
Adapter molecule crk

1

3

High-throughput

0.479

High

719370

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

719373

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

719375

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.479

High

719376

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

719379

SOSD1
Sclerostin domain-containing protein 1

1

1

Small-scale

0.479

High

719381

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

719382

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

719383

OPTN
Optineurin

1

1

High-throughput

0.479

High

719385

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

262379

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

719386

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

377965

PRIO
Major prion protein

1

2

High-throughput

0.445

High

517097

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

100544

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

524543

LYL1
Protein lyl-1

1

2

High-throughput

0.437

High

552067

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

719368

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

719377

EMC4
ER membrane protein complex subunit 4

1

3

High-throughput

0.437

High

719378

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.437

High

719388

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

719372

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.261

Low

719384

C170L
Cep170-like protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024