Protein: PK1IP
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)

Gene: PK1IP, PAK1IP1
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q9NWT1

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0008283 - cell population proliferation
GO:0009968 - negative regulation of signal transduction
GO:0042273 - ribosomal large subunit biogenesis
GO:0060021 - roof of mouth development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921998

RL30
Large ribosomal subunit protein eL30

2

3

High-throughput

0.726

High

1221480

ZC3H3
Zinc finger CCCH domain-containing protein 3

2

1

High-throughput

0.705

High

1333863

PKHF2
Pleckstrin homology domain-containing family F member 2

2

6

High-throughput

0.700

High

913797

RL7A
Large ribosomal subunit protein eL8

1

10

High-throughput

0.691

High

1343145

SSF1
Suppressor of SWI4 1 homolog

2

2

High-throughput

0.628

High

171852

WDR46
WD repeat-containing protein 46

1

18

High-throughput

0.618

High

1347386

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

8

High-throughput

0.618

High

418721

NPM
Nucleophosmin

2

8

High-throughput

0.611

High

842696

RL14
Large ribosomal subunit protein eL14

2

4

High-throughput

0.611

High

916921

RS6
Small ribosomal subunit protein eS6

2

4

High-throughput

0.611

High

1264674

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

348042

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

838314

MEOX2
Homeobox protein MOX-2

2

6

High-throughput

0.584

High

1295972

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.578

High

69630

B0UZZ8
Chromosome 6 open reading frame 11

1

17

High-throughput

0.575

High

489309

H14
Histone H1.4

2

11

High-throughput

0.574

High

900288

RL37A
Large ribosomal subunit protein eL43

2

3

High-throughput

0.574

High

914839

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

4

High-throughput

0.574

High

649781

RL10
Large ribosomal subunit protein uL16

2

5

High-throughput

0.558

High

909214

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

12

High-throughput

0.553

High

1171968

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.553

High

1343691

ANLN
Anillin

1

5

High-throughput

0.553

High

1151269

Q6FHY5
MEOX2 protein

2

6

High-throughput

0.544

High

271435

NPM3
Nucleoplasmin-3

1

8

High-throughput

0.536

High

273281

SURF6
Surfeit locus protein 6

1

2

High-throughput

0.536

High

620583

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

6

High-throughput

0.536

High

642638

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.536

High

736769

RL4
Large ribosomal subunit protein uL4

1

5

High-throughput

0.536

High

759863

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.536

High

773599

RL13A
Large ribosomal subunit protein uL13

1

8

High-throughput

0.536

High

781842

MNDA
Myeloid cell nuclear differentiation antigen

1

5

High-throughput

0.536

High

789561

RBM34
RNA-binding protein 34

1

18

High-throughput

0.536

High

790593

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

801425

KI67
Proliferation marker protein Ki-67

1

16

High-throughput

0.536

High

807562

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.536

High

907561

RS8
Small ribosomal subunit protein eS8

1

4

High-throughput

0.536

High

916411

RL23A
Large ribosomal subunit protein uL23

1

3

High-throughput

0.536

High

923249

RL11
Large ribosomal subunit protein uL5

1

5

High-throughput

0.536

High

951791

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.536

High

989971

RL18
Large ribosomal subunit protein eL18

1

4

High-throughput

0.536

High

1028847

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.536

High

1308788

RBM4B
RNA-binding protein 4B

1

16

High-throughput

0.536

High

1309646

MBB1A
Myb-binding protein 1A

1

4

High-throughput

0.536

High

1314633

RBM4
RNA-binding protein 4

1

15

High-throughput

0.536

High

1334563

LN28A
Protein lin-28 homolog A

1

9

High-throughput

0.536

High

1347031

RBM28
RNA-binding protein 28

1

14

High-throughput

0.536

High

1347384

LYAR
Cell growth-regulating nucleolar protein

1

3

High-throughput

0.536

High

1347392

ZN346
Zinc finger protein 346

1

4

High-throughput

0.536

High

1347394

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1347395

RL36
Large ribosomal subunit protein eL36

1

3

High-throughput

0.536

High

1026235

PAK1
Serine/threonine-protein kinase PAK 1

1

15

Small-scale

0.523

High

370556

ESR1
Estrogen receptor

2

19

High-throughput

0.521

High

1040714

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

1310681

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

180484

MAGB2
Melanoma-associated antigen B2

1

9

High-throughput

0.489

High

269910

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

18

High-throughput

0.489

High

401145

RLA0
Large ribosomal subunit protein uL10

1

6

High-throughput

0.489

High

445564

RSSA
Small ribosomal subunit protein uS2

1

3

High-throughput

0.489

High

470581

H2A1
Histone H2A type 1

1

7

High-throughput

0.489

High

550989

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.489

High

578165

RL17
Large ribosomal subunit protein uL22

1

5

High-throughput

0.489

High

739852

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.489

High

806711

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.489

High

853735

IMA5
Importin subunit alpha-5

1

7

High-throughput

0.489

High

922432

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.489

High

922734

RL10A
Large ribosomal subunit protein uL1

1

9

High-throughput

0.489

High

923562

RL8
Large ribosomal subunit protein uL2

1

3

High-throughput

0.489

High

971378

H11
Histone H1.1

1

11

High-throughput

0.489

High

971612

RL18A
Large ribosomal subunit protein eL20

1

2

High-throughput

0.489

High

992963

SRSF1
Serine/arginine-rich splicing factor 1

1

20

High-throughput

0.489

High

993852

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.489

High

1029131

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.489

High

1101019

RN151
RING finger protein 151

1

13

High-throughput

0.489

High

1187820

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

7

High-throughput

0.489

High

1347387

ZBT47
Zinc finger and BTB domain-containing protein 47

1

1

High-throughput

0.489

High

1347390

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.489

High

379938

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

760353

RL3
Large ribosomal subunit protein uL3

1

8

High-throughput

0.479

High

962995

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

Small-scale

0.479

High

1085991

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1294065

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1316915

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

14

High-throughput

0.479

High

1347385

RCC2
Protein RCC2

1

11

Small-scale

0.479

High

1347389

NOL12
Nucleolar protein 12

1

1

High-throughput

0.479

High

1057685

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

10

High-throughput

0.445

High

679399

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

5

High-throughput

0.439

High

981751

REL
Proto-oncogene c-Rel

1

16

High-throughput

0.439

High

123041

MEN1
Menin

1

3

High-throughput

0.437

High

214392

SPOP
Speckle-type POZ protein

1

6

High-throughput

0.437

High

233653

NUPR1
Nuclear protein 1

1

3

High-throughput

0.437

High

233904

HBP1
HMG box-containing protein 1

1

11

High-throughput

0.437

High

245013

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.437

High

298833

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.437

High

374971

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.437

High

442540

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.437

High

553875

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

652413

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

721604

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

801965

RECQ1
ATP-dependent DNA helicase Q1

1

20

High-throughput

0.437

High

824447

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

9

High-throughput

0.437

High

877918

FOXA1
Hepatocyte nuclear factor 3-alpha

1

7

High-throughput

0.437

High

882604

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.437

High

959712

VIGLN
Vigilin

1

17

High-throughput

0.437

High

1029944

TIF1B
Transcription intermediary factor 1-beta

1

19

High-throughput

0.437

High

1036140

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.437

High

1042661

CUL3
Cullin-3

1

20

Small-scale

0.437

High

1064195

TNIP1
TNFAIP3-interacting protein 1

1

10

High-throughput

0.437

High

1201715

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.437

High

1236532

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.437

High

1256432

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.437

High

1269754

ESR2
Estrogen receptor beta

1

18

High-throughput

0.437

High

1301809

RANB9
Ran-binding protein 9

1

19

High-throughput

0.437

High

1347388

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.437

High

1347393

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.437

High

1347391

AGO1
Protein argonaute-1

1

1

High-throughput

0.407

High

1293518

PRR11
Proline-rich protein 11

2

0

High-throughput

0.318

High

130279

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.279

Low

1054944

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1291216

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.279

Low

1295856

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1311139

ZNF2
Zinc finger protein 2

1

0

High-throughput

0.279

Low

1343992

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

1

0

High-throughput

0.279

Low

1311254

TINF2
TERF1-interacting nuclear factor 2

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024