Protein: PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)

Gene: PI42A, PIP4K2A
Organism: Homo sapiens
Interactions: 192
UniProt ID: P48426

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0001917 - photoreceptor inner segment
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817712

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

5

13

High-throughput

0.927

High

817655

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

3

13

High-throughput

0.871

High

817736

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

13

High-throughput

0.811

High

244094

BRD4
Bromodomain-containing protein 4

4

11

High-throughput

0.694

High

216467

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

6

High-throughput

0.675

High

817676

STK11
Serine/threonine-protein kinase STK11

3

3

High-throughput

0.675

High

307778

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

3

2

High-throughput

0.667

High

586616

CSK22
Casein kinase II subunit alpha'

3

8

High-throughput

0.667

High

631373

BRD2
Bromodomain-containing protein 2

3

10

High-throughput

0.667

High

817729

EAF1
ELL-associated factor 1

3

3

High-throughput

0.667

High

236714

CCNT1
Cyclin-T1

3

0

High-throughput

0.646

High

130147

ELL2
RNA polymerase II elongation factor ELL2

2

2

High-throughput

0.628

High

217013

PRIC3
Prickle planar cell polarity protein 3

2

2

High-throughput

0.628

High

253542

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

2

High-throughput

0.628

High

257035

DJC13
DnaJ homolog subfamily C member 13

2

4

High-throughput

0.628

High

309452

MTMR5
Myotubularin-related protein 5

2

8

High-throughput

0.628

High

567657

UBF1
Nucleolar transcription factor 1

2

2

High-throughput

0.628

High

788012

AF9
Protein AF-9

2

1

High-throughput

0.628

High

817643

AFF3
AF4/FMR2 family member 3

2

3

High-throughput

0.628

High

817644

ELL
RNA polymerase II elongation factor ELL

2

2

High-throughput

0.628

High

817645

BRPF1
Peregrin

2

2

High-throughput

0.628

High

817656

ENL
Protein ENL

2

1

High-throughput

0.628

High

817660

TCOF
Treacle protein

2

2

High-throughput

0.628

High

817662

MTMR1
Myotubularin-related protein 1

2

4

High-throughput

0.628

High

817669

KANK1
KN motif and ankyrin repeat domain-containing protein 1

2

3

High-throughput

0.628

High

817671

NOLC1
Nucleolar and coiled-body phosphoprotein 1

2

4

High-throughput

0.628

High

817674

RNPS1
RNA-binding protein with serine-rich domain 1

2

2

High-throughput

0.628

High

817679

CHD9
Chromodomain-helicase-DNA-binding protein 9

2

3

High-throughput

0.628

High

817683

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

2

4

High-throughput

0.628

High

817685

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

2

High-throughput

0.628

High

817687

EDC4
Enhancer of mRNA-decapping protein 4

2

2

High-throughput

0.628

High

817689

RFWD3
E3 ubiquitin-protein ligase RFWD3

2

1

High-throughput

0.628

High

817691

MEX3B
RNA-binding protein MEX3B

2

2

High-throughput

0.628

High

817694

STRAA
STE20-related kinase adapter protein alpha

2

7

High-throughput

0.628

High

817697

RHG22
Rho GTPase-activating protein 22

2

4

High-throughput

0.628

High

817704

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

2

3

High-throughput

0.628

High

817718

RTF1
RNA polymerase-associated protein RTF1 homolog

2

1

High-throughput

0.628

High

817724

EAF2
ELL-associated factor 2

2

3

High-throughput

0.628

High

817727

SAHH3
Adenosylhomocysteinase 3

2

6

High-throughput

0.628

High

817734

MINT
Msx2-interacting protein

2

2

High-throughput

0.628

High

817737

LZTS2
Leucine zipper putative tumor suppressor 2

2

4

High-throughput

0.628

High

817738

SRSF8
Serine/arginine-rich splicing factor 8

2

3

High-throughput

0.628

High

817746

STRAB
STE20-related kinase adapter protein beta

2

8

High-throughput

0.628

High

817749

PININ
Pinin

2

1

High-throughput

0.628

High

817750

WDR26
WD repeat-containing protein 26

2

6

High-throughput

0.628

High

817751

ELL3
RNA polymerase II elongation factor ELL3

2

2

High-throughput

0.628

High

817753

CWC22
Pre-mRNA-splicing factor CWC22 homolog

2

1

High-throughput

0.628

High

817755

E41L5
Band 4.1-like protein 5

2

6

High-throughput

0.628

High

817767

AFF4
AF4/FMR2 family member 4

2

3

High-throughput

0.628

High

817770

ACINU
Apoptotic chromatin condensation inducer in the nucleus

2

1

High-throughput

0.628

High

817772

SET1B
Histone-lysine N-methyltransferase SETD1B

2

3

High-throughput

0.628

High

817773

SRRM2
Serine/arginine repetitive matrix protein 2

2

2

High-throughput

0.628

High

817778

CAB39
Calcium-binding protein 39

2

1

High-throughput

0.628

High

817649

UBE2H
Ubiquitin-conjugating enzyme E2 H

2

4

High-throughput

0.611

High

817654

CSK21
Casein kinase II subunit alpha

2

8

High-throughput

0.611

High

817672

BRD3
Bromodomain-containing protein 3

3

11

High-throughput

0.609

High

817684

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

3

2

High-throughput

0.609

High

551402

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

0

High-throughput

0.602

High

722571

T2FA
General transcription factor IIF subunit 1

2

0

High-throughput

0.602

High

817659

PPIG
Peptidyl-prolyl cis-trans isomerase G

2

0

High-throughput

0.602

High

817661

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

High-throughput

0.602

High

817703

CLASR
CLK4-associating serine/arginine rich protein

2

0

High-throughput

0.602

High

817713

PNISR
Arginine/serine-rich protein PNISR

2

0

High-throughput

0.602

High

817728

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

High-throughput

0.602

High

817757

RAD18
E3 ubiquitin-protein ligase RAD18

2

0

High-throughput

0.602

High

817762

CXXC1
CXXC-type zinc finger protein 1

2

0

High-throughput

0.602

High

817763

IKBL1
NF-kappa-B inhibitor-like protein 1

2

0

High-throughput

0.602

High

817777

AP3M1
AP-3 complex subunit mu-1

2

0

High-throughput

0.602

High

496541

TAU
Microtubule-associated protein tau

2

5

High-throughput

0.601

High

119933

AP3B1
AP-3 complex subunit beta-1

2

5

High-throughput

0.574

High

147058

NEMP1
Nuclear envelope integral membrane protein 1

2

1

High-throughput

0.574

High

817642

AFF1
AF4/FMR2 family member 1

2

4

High-throughput

0.574

High

817681

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

2

2

High-throughput

0.574

High

817696

HDGR2
Hepatoma-derived growth factor-related protein 2

2

2

High-throughput

0.574

High

817720

C102A
Coiled-coil domain-containing protein 102A

2

1

High-throughput

0.574

High

817722

ZN428
Zinc finger protein 428

2

2

High-throughput

0.574

High

817723

CSTOS
Protein CUSTOS

2

1

High-throughput

0.574

High

817730

LENG8
Leukocyte receptor cluster member 8

2

1

High-throughput

0.574

High

817752

GPBL1
Vasculin-like protein 1

2

2

High-throughput

0.574

High

817766

SUN2
SUN domain-containing protein 2

2

2

High-throughput

0.574

High

817769

GPTC8
G patch domain-containing protein 8

2

2

High-throughput

0.574

High

817774

DIP2C
Disco-interacting protein 2 homolog C

2

1

High-throughput

0.574

High

817735

MEIS3
Homeobox protein Meis3

2

1

High-throughput

0.553

High

571097

EGLN
Endoglin

1

1

High-throughput

0.536

High

617257

SP100
Nuclear autoantigen Sp-100

1

5

High-throughput

0.536

High

672644

CD6
T-cell differentiation antigen CD6

1

3

High-throughput

0.536

High

817647

MAX
Protein max

1

5

High-throughput

0.536

High

817658

TP53B
TP53-binding protein 1

1

2

High-throughput

0.536

High

817666

SCRIB
Protein scribble homolog

1

2

High-throughput

0.536

High

817690

RFIP1
Rab11 family-interacting protein 1

1

2

High-throughput

0.536

High

817716

MADD
MAP kinase-activating death domain protein

1

5

High-throughput

0.536

High

817733

IWS1
Protein IWS1 homolog

1

1

High-throughput

0.536

High

817743

SETD2
Histone-lysine N-methyltransferase SETD2

1

2

High-throughput

0.536

High

817745

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.536

High

817747

NUAK2
NUAK family SNF1-like kinase 2

1

2

High-throughput

0.536

High

817754

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

3

High-throughput

0.536

High

817756

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

High-throughput

0.536

High

817771

TAOK2
Serine/threonine-protein kinase TAO2

1

5

High-throughput

0.536

High

817775

E41L3
Band 4.1-like protein 3

1

4

High-throughput

0.536

High

817776

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.518

High

685843

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

817646

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.513

High

817650

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.513

High

817651

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.513

High

817652

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

817705

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.513

High

817764

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.513

High

616685

KS6B1
Ribosomal protein S6 kinase beta-1

1

4

Small-scale

0.501

High

817711

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

817725

ATG4C
Cysteine protease ATG4C

1

2

High-throughput

0.489

High

817731

CC85A
Coiled-coil domain-containing protein 85A

1

3

High-throughput

0.489

High

196969

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

2

High-throughput

0.479

High

202393

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

1

High-throughput

0.479

High

226812

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

262393

TULP3
Tubby-related protein 3

1

2

High-throughput

0.479

High

322320

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

346205

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

506920

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.479

High

575328

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

632641

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

650629

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

674631

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

1

High-throughput

0.479

High

714496

GRK5
G protein-coupled receptor kinase 5

1

4

High-throughput

0.479

High

719931

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

817638

KC1A
Casein kinase I isoform alpha

1

9

High-throughput

0.479

High

817639

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

817640

KC1E
Casein kinase I isoform epsilon

1

11

High-throughput

0.479

High

817648

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

817653

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.479

High

817657

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

817663

CUL4B
Cullin-4B

1

2

Small-scale

0.479

High

817664

PTC1
Protein patched homolog 1

1

3

Small-scale

0.479

High

817667

ELOA1
Elongin-A

1

1

High-throughput

0.479

High

817668

SRC8
Src substrate cortactin

1

1

High-throughput

0.479

High

817675

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.479

High

817700

PHF6
PHD finger protein 6

1

2

High-throughput

0.479

High

817707

KC1AL
Casein kinase I isoform alpha-like

1

9

High-throughput

0.479

High

817708

PR38A
Pre-mRNA-splicing factor 38A

1

1

High-throughput

0.479

High

817710

CSK23
Casein kinase II subunit alpha 3

1

8

High-throughput

0.479

High

817732

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.479

High

817741

RIOK2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.479

High

817744

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.479

High

817758

DCA13
DDB1- and CUL4-associated factor 13

1

4

High-throughput

0.479

High

817759

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.479

High

817761

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.479

High

817765

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

214879

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

296644

SLIT2
Slit homolog 2 protein

1

0

High-throughput

0.458

High

335070

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.458

High

342551

CAH2
Carbonic anhydrase 2

1

0

High-throughput

0.458

High

445317

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

552190

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

608895

SPR2E
Small proline-rich protein 2E

1

0

High-throughput

0.458

High

817641

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

817670

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.458

High

817673

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.458

High

817677

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

817686

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

817695

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

817698

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

817706

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.458

High

817714

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

817715

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.458

High

817717

H1X
Histone H1.10

1

0

High-throughput

0.458

High

817726

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

817739

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

817748

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

817760

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.458

High

500749

CLUS
Clusterin

1

0

High-throughput

0.438

High

817678

KNOP1
Lysine-rich nucleolar protein 1

1

1

High-throughput

0.437

High

817680

CI114
Putative methyltransferase C9orf114

1

1

High-throughput

0.437

High

817688

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

817692

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

817719

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

2

High-throughput

0.437

High

817781

MAFB
Transcription factor MafB

1

3

High-throughput

0.437

High

401616

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

817665

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

817701

GPAM1
GPALPP motifs-containing protein 1

2

0

High-throughput

0.328

High

817702

SELH
Selenoprotein H

2

0

High-throughput

0.328

High

817721

ARK2N
Protein ARK2N

2

0

High-throughput

0.328

High

817699

F90A1
Protein FAM90A1

1

0

High-throughput

0.279

Low

817780

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

100583

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

260482

PITX3
Pituitary homeobox 3

1

0

Small-scale

0.249

Low

595591

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.249

Low

817682

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.249

Low

817693

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

817709

FA98A
Protein FAM98A

1

0

High-throughput

0.249

Low

817740

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low

817742

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.249

Low

817768

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.249

Low

817779

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024