Protein: NR1I3
Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)

Gene: NR1I3
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q14994

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1061326

NCOA1
Nuclear receptor coactivator 1

4

20

High-throughput

0.897

High

587170

RXRA
Retinoic acid receptor RXR-alpha

4

20

Small-scale

0.888

High

1061324

NCOA2
Nuclear receptor coactivator 2

3

20

High-throughput

0.861

High

369623

ESR1
Estrogen receptor

2

19

High-throughput

0.737

High

850859

NR0B1
Nuclear receptor subfamily 0 group B member 1

1

20

Small-scale

0.724

High

225378

MED14
Mediator of RNA polymerase II transcription subunit 14

3

20

High-throughput

0.667

High

273432

PPM1B
Protein phosphatase 1B

3

2

High-throughput

0.667

High

475028

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

9

High-throughput

0.667

High

1061325

MED1
Mediator of RNA polymerase II transcription subunit 1

3

20

High-throughput

0.667

High

1061332

MED4
Mediator of RNA polymerase II transcription subunit 4

3

6

High-throughput

0.667

High

1061333

MED17
Mediator of RNA polymerase II transcription subunit 17

3

5

High-throughput

0.667

High

1061335

MED13
Mediator of RNA polymerase II transcription subunit 13

3

8

High-throughput

0.667

High

1061337

MED23
Mediator of RNA polymerase II transcription subunit 23

3

5

High-throughput

0.667

High

782544

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

Small-scale

0.647

High

1061339

NCOA3
Nuclear receptor coactivator 3

1

20

Small-scale

0.647

High

431858

HS90A
Heat shock protein HSP 90-alpha

3

18

Small-scale

0.640

High

265324

MED24
Mediator of RNA polymerase II transcription subunit 24

2

7

High-throughput

0.611

High

907028

PRS8
26S proteasome regulatory subunit 8

2

20

Small-scale

0.584

High

912636

SMD3
Small nuclear ribonucleoprotein Sm D3

1

7

High-throughput

0.541

High

504101

HSP7C
Heat shock cognate 71 kDa protein

1

16

High-throughput

0.536

High

564076

HSP76
Heat shock 70 kDa protein 6

1

16

High-throughput

0.536

High

871570

HSP72
Heat shock-related 70 kDa protein 2

1

16

High-throughput

0.536

High

1061328

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

20

Small-scale

0.527

High

345439

FOS
Protein c-Fos

1

20

High-throughput

0.515

High

656405

PIT1
Pituitary-specific positive transcription factor 1

1

20

Small-scale

0.501

High

1061336

DNM3L
DNA

1

7

Small-scale

0.501

High

1061338

SNX13
Sorting nexin-13

1

3

High-throughput

0.494

High

365194

FRIH
Ferritin heavy chain

1

1

High-throughput

0.481

High

522991

SRC
Proto-oncogene tyrosine-protein kinase Src

1

11

Small-scale

0.481

High

653978

MAP4
Microtubule-associated protein 4

1

20

High-throughput

0.481

High

798664

PRS6B
26S proteasome regulatory subunit 6B

1

20

Small-scale

0.481

High

170370

TIF1A
Transcription intermediary factor 1-alpha

1

20

Small-scale

0.479

High

438177

HS90B
Heat shock protein HSP 90-beta

1

18

High-throughput

0.479

High

668694

PML
Protein PML

1

20

Small-scale

0.479

High

714226

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.479

High

1061327

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.479

High

1061329

MED12
Mediator of RNA polymerase II transcription subunit 12

1

20

High-throughput

0.479

High

1061330

MED15
Mediator of RNA polymerase II transcription subunit 15

1

20

High-throughput

0.479

High

1061331

KPCD2
Serine/threonine-protein kinase D2

1

12

High-throughput

0.479

High

1061334

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

20

Small-scale

0.479

High

100771

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

167919

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High


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Last updated: 15 Jul 2024