Protein: FL2D
Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein)

Gene: FL2D, WTAP
Organism: Homo sapiens
Interactions: 194
UniProt ID: Q15007

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1062758

MTA70
N6-adenosine-methyltransferase catalytic subunit

6

4

Small-scale

0.731

High

1033644

IKZF1
DNA-binding protein Ikaros

6

0

High-throughput

0.707

High

585911

WT1
Wilms tumor protein

4

0

Small-scale

0.670

High

1062750

ABRX1
BRCA1-A complex subunit Abraxas 1

3

1

High-throughput

0.667

High

1062766

CBLL2
E3 ubiquitin-protein ligase CBLL2

3

1

High-throughput

0.667

High

1062787

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

3

1

High-throughput

0.665

High

1062729

FL2D
Pre-mRNA-splicing regulator WTAP

3

1

High-throughput

0.653

High

796276

MAGAB
Melanoma-associated antigen 11

3

0

High-throughput

0.639

High

1062790

MET14
N6-adenosine-methyltransferase non-catalytic subunit

2

4

Small-scale

0.618

High

927060

1433Z
14-3-3 protein zeta/delta

2

3

High-throughput

0.611

High

932165

ACTC
Actin, alpha cardiac muscle 1

2

1

High-throughput

0.611

High

1046038

DX39B
Spliceosome RNA helicase DDX39B

2

2

High-throughput

0.611

High

1062745

VIR
Protein virilizer homolog

2

1

High-throughput

0.611

High

637421

PSA1
Proteasome subunit alpha type-1

2

2

High-throughput

0.606

High

1062780

HTF4
Transcription factor 12

2

1

High-throughput

0.606

High

1062755

3BP5L
SH3 domain-binding protein 5-like

2

0

High-throughput

0.602

High

504103

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.585

High

917291

H4
Histone H4

2

0

High-throughput

0.585

High

1046831

BYST
Bystin

2

0

High-throughput

0.580

High

1062730

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.580

High

1062733

ZN239
Zinc finger protein 239

2

0

High-throughput

0.580

High

1062756

ZN572
Zinc finger protein 572

2

0

High-throughput

0.580

High

117144

DX39A
ATP-dependent RNA helicase DDX39A

1

2

High-throughput

0.536

High

256257

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

1

High-throughput

0.536

High

359352

K1C14
Keratin, type I cytoskeletal 14

1

8

High-throughput

0.536

High

359493

K2C6A
Keratin, type II cytoskeletal 6A

1

7

High-throughput

0.536

High

359953

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.536

High

376243

ANXA1
Annexin A1

1

1

High-throughput

0.536

High

380613

K2C1
Keratin, type II cytoskeletal 1

1

6

High-throughput

0.536

High

427562

ANXA2
Annexin A2

1

1

High-throughput

0.536

High

441286

RU2B
U2 small nuclear ribonucleoprotein B''

1

1

High-throughput

0.536

High

443524

VIME
Vimentin

1

6

High-throughput

0.536

High

445049

K1C16
Keratin, type I cytoskeletal 16

1

8

High-throughput

0.536

High

502113

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

531366

K1C10
Keratin, type I cytoskeletal 10

1

9

High-throughput

0.536

High

531574

K2C5
Keratin, type II cytoskeletal 5

1

5

High-throughput

0.536

High

598124

FLNA
Filamin-A

1

1

High-throughput

0.536

High

685687

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.536

High

724080

K1C9
Keratin, type I cytoskeletal 9

1

8

High-throughput

0.536

High

729091

K22E
Keratin, type II cytoskeletal 2 epidermal

1

6

High-throughput

0.536

High

751635

GRP75
Stress-70 protein, mitochondrial

1

2

High-throughput

0.536

High

867204

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

1

High-throughput

0.536

High

891773

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.536

High

903942

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

High-throughput

0.536

High

909578

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

962095

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

989297

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.536

High

1062731

PCBP2
Poly(rC)-binding protein 2

1

1

High-throughput

0.536

High

1062738

FILA2
Filaggrin-2

1

1

High-throughput

0.536

High

1062741

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.536

High

1062747

ZSC25
Zinc finger and SCAN domain-containing protein 25

1

1

High-throughput

0.536

High

1062748

H3C
Histone H3.3C

1

1

High-throughput

0.536

High

1062754

HAKAI
E3 ubiquitin-protein ligase Hakai

1

1

High-throughput

0.536

High

1062761

HORN
Hornerin

1

1

High-throughput

0.536

High

1062767

RB15B
Putative RNA-binding protein 15B

1

2

High-throughput

0.536

High

1062778

RBM15
RNA-binding protein 15

1

3

High-throughput

0.536

High

1062785

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.536

High

1062808

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.536

High

781895

PERI
Peripherin

1

6

High-throughput

0.515

High

241308

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

0

High-throughput

0.513

High

241531

H2B1K
Histone H2B type 1-K

1

0

High-throughput

0.513

High

276584

TPC6A
Trafficking protein particle complex subunit 6A

1

0

High-throughput

0.513

High

304171

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.513

High

345082

CYTA
Cystatin-A

1

0

High-throughput

0.513

High

363794

ALBU
Albumin

1

0

High-throughput

0.513

High

428216

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

440518

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

470025

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

475778

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.513

High

495528

THIO
Thioredoxin

1

0

High-throughput

0.513

High

508532

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

548909

NDKA
Nucleoside diphosphate kinase A

1

0

High-throughput

0.513

High

551708

DESP
Desmoplakin

1

0

High-throughput

0.513

High

571459

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.513

High

606424

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.513

High

682818

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

0

High-throughput

0.513

High

683087

CASPE
Caspase-14

1

0

High-throughput

0.513

High

739718

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

789792

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

794258

MSH2
DNA mismatch repair protein Msh2

1

0

High-throughput

0.513

High

854728

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

0

High-throughput

0.513

High

928305

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.513

High

932702

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.513

High

958912

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.513

High

988889

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.513

High

996676

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1029439

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.513

High

1046220

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

1062734

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1062739

SAMD9
Sterile alpha motif domain-containing protein 9

1

0

High-throughput

0.513

High

1062753

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

1062770

GRK7
Rhodopsin kinase GRK7

1

0

High-throughput

0.513

High

1062772

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

0

High-throughput

0.513

High

1062774

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.513

High

1062776

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.513

High

1062781

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

1062783

SH3G2
Endophilin-A1

1

0

High-throughput

0.513

High

1062791

BRMS1
Breast cancer metastasis-suppressor 1

1

0

High-throughput

0.513

High

1062799

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.513

High

1062802

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

1062807

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.513

High

646902

1433T
14-3-3 protein theta

1

3

High-throughput

0.501

High

203939

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

791567

HD
Huntingtin

1

0

High-throughput

0.493

High

868187

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

893350

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

363154

FINC
Fibronectin

1

1

High-throughput

0.489

High

380477

K2C6B
Keratin, type II cytoskeletal 6B

1

6

High-throughput

0.489

High

418958

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.489

High

428683

TRY1
Serine protease 1

1

1

High-throughput

0.489

High

451256

TPM1
Tropomyosin alpha-1 chain

1

2

High-throughput

0.489

High

714757

TRY3
Trypsin-3

1

1

High-throughput

0.489

High

827384

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.489

High

932004

TPM4
Tropomyosin alpha-4 chain

1

2

High-throughput

0.489

High

980258

K1C17
Keratin, type I cytoskeletal 17

1

8

High-throughput

0.489

High

984588

CALD1
Caldesmon

1

1

High-throughput

0.489

High

984700

COEA1
Collagen alpha-1(XIV) chain

1

1

High-throughput

0.489

High

1055186

K1H2
Keratin, type I cuticular Ha2

1

8

High-throughput

0.489

High

1062757

K2C1B
Keratin, type II cytoskeletal 1b

1

7

High-throughput

0.489

High

1062765

K2C78
Keratin, type II cytoskeletal 78

1

8

High-throughput

0.489

High

1062796

KRT82
Keratin, type II cuticular Hb2

1

5

High-throughput

0.489

High

174899

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

294840

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

346817

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379416

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

569742

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

656231

PSA5
Proteasome subunit alpha type-5

1

1

Small-scale

0.479

High

781367

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.479

High

801884

RECQ1
ATP-dependent DNA helicase Q1

1

2

High-throughput

0.479

High

1062735

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1062746

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1062775

SH3K1
SH3 domain-containing kinase-binding protein 1

1

2

High-throughput

0.479

High

1062803

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.479

High

1062732

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.460

High

1062792

EXOS4
Exosome complex component RRP41

1

0

High-throughput

0.460

High

1062795

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

1062798

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.460

High

122767

MEN1
Menin

1

0

High-throughput

0.458

High

431859

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

442168

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

556869

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

658945

MK01
Mitogen-activated protein kinase 1

1

0

Small-scale

0.458

High

737812

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

1018960

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1062749

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1062752

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1062759

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1062763

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.458

High

1062768

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1062769

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1062773

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1062779

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1062786

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1062788

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1062794

ANLN
Anillin

1

0

High-throughput

0.458

High

1062797

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1062800

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1062805

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1062806

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.458

High

402025

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

822602

HSP77
Putative heat shock 70 kDa protein 7

1

1

High-throughput

0.445

High

828233

CENPA
Histone H3-like centromeric protein A

1

1

Small-scale

0.445

High

1062737

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

1062801

DDX41
Probable ATP-dependent RNA helicase DDX41

1

1

High-throughput

0.445

High

1062743

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1062736

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

1062762

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.426

High

1062789

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

353166

KV133
Immunoglobulin kappa variable 1-33

1

2

High-throughput

0.407

High

353177

KVD12
Immunoglobulin kappa variable 1D-12

1

2

High-throughput

0.407

High

946339

LV321
Immunoglobulin lambda variable 3-21

1

2

High-throughput

0.407

High

1062764

VPS52
Vacuolar protein sorting-associated protein 52 homolog

4

0

High-throughput

0.365

High

1062784

KXDL1
KxDL motif-containing protein 1

2

0

High-throughput

0.328

High

1062777

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.318

High

1062751

ABH15
Protein ABHD15

2

0

High-throughput

0.316

High

469863

CO4A
Complement C4-A

1

0

High-throughput

0.279

Low

813033

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

946523

DCD
Dermcidin

1

0

High-throughput

0.279

Low

1062742

KPLCE
Protein KPLCE

1

0

High-throughput

0.279

Low

1062744

CR063
Uncharacterized protein C18orf63

1

0

High-throughput

0.279

Low

1062760

ZSWM9
Uncharacterized protein ZSWIM9

1

0

High-throughput

0.279

Low

1062771

PIGB
GPI mannosyltransferase 3

1

0

High-throughput

0.279

Low

1062782

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1062804

COR1C
Coronin-1C

1

0

High-throughput

0.279

Low

231525

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

281631

WFS1
Wolframin

1

0

High-throughput

0.268

Low

427083

CATD
Cathepsin D

1

0

High-throughput

0.268

Low

100775

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

611559

CAH4
Carbonic anhydrase 4

1

0

Small-scale

0.249

Low

1062793

NGB
Neuroglobin

1

0

High-throughput

0.249

Low

200562

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

353669

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.232

Low

1062740

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024