Protein: PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) (Phosphoenolpyruvate carboxykinase 2, mitochondrial) (mtPCK2)

Gene: PCKGM, PCK2
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q16822

Gene Ontology (top 5):
GO:0004611 - phosphoenolpyruvate carboxykinase activity
GO:0004613 - phosphoenolpyruvate carboxykinase (GTP) activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724439

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

2

0

High-throughput

0.770

High

1087859

AHNK2
Protein AHNAK2

2

1

High-throughput

0.628

High

1087888

ZMYM2
Zinc finger MYM-type protein 2

2

4

High-throughput

0.628

High

499785

CH60
60 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.611

High

526398

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

2

0

High-throughput

0.602

High

1087887

RCOR3
REST corepressor 3

2

0

High-throughput

0.602

High

1087892

SUFU
Suppressor of fused homolog

2

0

High-throughput

0.602

High

1051223

ZMYM3
Zinc finger MYM-type protein 3

2

4

High-throughput

0.574

High

1087855

ZMYM4
Zinc finger MYM-type protein 4

2

5

High-throughput

0.574

High

1087865

BPIB1
BPI fold-containing family B member 1

2

1

High-throughput

0.574

High

1087883

BPIA1
BPI fold-containing family A member 1

2

1

High-throughput

0.574

High

1087891

DMBT1
Deleted in malignant brain tumors 1 protein

2

2

High-throughput

0.574

High

397166

KPCG
Protein kinase C gamma type

2

2

High-throughput

0.571

High

969090

KPCE
Protein kinase C epsilon type

2

2

High-throughput

0.571

High

374303

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.559

High

950198

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.549

High

999591

AHNK
Neuroblast differentiation-associated protein AHNAK

1

1

High-throughput

0.536

High

299770

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

737350

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.513

High

1087858

HAKAI
E3 ubiquitin-protein ligase Hakai

1

0

Small-scale

0.513

High

1087860

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1087874

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.513

High

1087875

BBS2
Bardet-Biedl syndrome 2 protein

1

0

High-throughput

0.513

High

1087877

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

1087879

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

1087880

MUC13
Mucin-13

1

0

High-throughput

0.513

High

1087886

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

High-throughput

0.513

High

354066

IGHA1
Immunoglobulin heavy constant alpha 1

2

1

High-throughput

0.504

High

354160

IGHA2
Immunoglobulin heavy constant alpha 2

2

1

High-throughput

0.504

High

394810

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

998784

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.481

High

227598

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

377361

GCR
Glucocorticoid receptor

1

3

High-throughput

0.479

High

792993

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

3

High-throughput

0.479

High

850075

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

903264

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

921586

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.479

High

1087864

COP1
E3 ubiquitin-protein ligase COP1

1

4

High-throughput

0.479

High

1087868

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1087872

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1087876

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

325190

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

440537

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

827947

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.458

High

882334

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1020439

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1066182

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1072746

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.458

High

1086582

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1087862

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

1087863

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1087867

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1087881

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1087889

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1087890

TES
Testin

1

0

High-throughput

0.458

High

1087893

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

1

High-throughput

0.445

High

346918

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

824069

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

980691

TLE2
Transducin-like enhancer protein 2

1

3

High-throughput

0.437

High

1029484

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

1043020

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1087873

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.437

High

1062230

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

Small-scale

0.426

High

1087854

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1087885

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

261830

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.328

High

570260

NEUM
Neuromodulin

2

0

High-throughput

0.328

High

1087869

PAUF
Pancreatic adenocarcinoma up-regulated factor

2

0

High-throughput

0.328

High

1087878

LACRT
Extracellular glycoprotein lacritin

2

0

High-throughput

0.328

High

1087882

MUC5B
Mucin-5B

2

0

High-throughput

0.328

High

353419

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.279

Low

1067503

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1087866

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.279

Low

1087870

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1087871

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

1087884

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.279

Low

100806

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

123611

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.249

Low

214282

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

384919

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1062154

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

Small-scale

0.249

Low

1062531

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

1087856

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1087857

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1087861

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024