Protein: SYDE1
Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1)

Gene: SYDE1
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q6ZW31

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0007165 - signal transduction
GO:0016477 - cell migration
GO:0030036 - actin cytoskeleton organization
GO:0030695 - GTPase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

120954

APBB1
Amyloid beta precursor protein binding family B member 1

4

3

High-throughput

0.691

High

909718

1433E
14-3-3 protein epsilon

2

11

High-throughput

0.628

High

253370

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

17

High-throughput

0.618

High

545459

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564582

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

892446

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894153

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

925379

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1173134

DEP1B
DEP domain-containing protein 1B

1

15

High-throughput

0.618

High

1173150

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1173152

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1173164

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

9

High-throughput

0.618

High

1173137

SH3K1
SH3 domain-containing kinase-binding protein 1

2

20

High-throughput

0.611

High

1173167

KLDC2
Kelch domain-containing protein 2

2

5

High-throughput

0.574

High

896769

ARP3
Actin-related protein 3

1

17

High-throughput

0.553

High

647029

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

683476

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

904754

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

982181

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

214968

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

2

3

High-throughput

0.521

High

687236

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

3

High-throughput

0.521

High

833460

RBM25
RNA-binding protein 25

2

11

High-throughput

0.521

High

841788

CDK9
Cyclin-dependent kinase 9

2

5

High-throughput

0.521

High

857486

HMGA2
High mobility group protein HMGI-C

2

1

High-throughput

0.521

High

970801

DSG1
Desmoglein-1

2

8

High-throughput

0.521

High

1134345

KPRP
Keratinocyte proline-rich protein

2

1

High-throughput

0.521

High

1173128

PHF6
PHD finger protein 6

2

4

High-throughput

0.521

High

1173138

P5CR2
Pyrroline-5-carboxylate reductase 2

2

3

High-throughput

0.521

High

1173147

MMTA2
Multiple myeloma tumor-associated protein 2

2

1

High-throughput

0.521

High

395007

A4
Amyloid-beta precursor protein

1

8

High-throughput

0.489

High

987521

APLP2
Amyloid beta precursor like protein 2

1

8

High-throughput

0.489

High

1121230

KLH22
Kelch-like protein 22

1

3

High-throughput

0.489

High

1173136

APBB2
Amyloid beta precursor protein binding family B member 2

1

3

High-throughput

0.489

High

1173140

LURA1
Leucine rich adaptor protein 1

1

1

High-throughput

0.489

High

1173166

RP3A
Rabphilin-3A

1

1

High-throughput

0.489

High

196468

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.479

High

598489

NF1
Neurofibromin

1

9

High-throughput

0.479

High

876424

AFAD
Afadin

1

20

High-throughput

0.479

High

1022411

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

6

High-throughput

0.479

High

1109671

TBC25
TBC1 domain family member 25

1

2

High-throughput

0.479

High

1136458

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

9

High-throughput

0.479

High

1173126

PHLB2
Pleckstrin homology-like domain family B member 2

1

14

High-throughput

0.479

High

1173142

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.479

High

1173143

TESK2
Dual specificity testis-specific protein kinase 2

1

3

High-throughput

0.479

High

1173146

RTKN
Rhotekin

1

2

High-throughput

0.479

High

1173153

KI13B
Kinesin-like protein KIF13B

1

7

High-throughput

0.479

High

1173158

LIMA1
LIM domain and actin-binding protein 1

1

8

High-throughput

0.479

High

1173160

NGAP
Ras GTPase-activating protein nGAP

1

9

High-throughput

0.479

High

1173165

GAB2
GRB2-associated-binding protein 2

1

17

High-throughput

0.479

High

475950

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.457

High

100888

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

162909

XPO1
Exportin-1

1

17

High-throughput

0.437

High

166579

DCLK1
Serine/threonine-protein kinase DCLK1

1

10

High-throughput

0.437

High

216941

KIF1C
Kinesin-like protein KIF1C

1

7

High-throughput

0.437

High

230885

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

5

High-throughput

0.437

High

237245

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.437

High

264339

GGYF1
GRB10-interacting GYF protein 1

1

9

High-throughput

0.437

High

316261

NADK
NAD kinase

1

1

High-throughput

0.437

High

629145

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.437

High

673493

MPIP2
M-phase inducer phosphatase 2

1

4

High-throughput

0.437

High

673598

MPIP3
M-phase inducer phosphatase 3

1

4

High-throughput

0.437

High

685714

PRDX2
Peroxiredoxin-2

1

6

High-throughput

0.437

High

853340

IMA1
Importin subunit alpha-1

1

5

High-throughput

0.437

High

880764

HDAC4
Histone deacetylase 4

1

9

High-throughput

0.437

High

901383

CH10
10 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.437

High

960384

CDK16
Cyclin-dependent kinase 16

1

4

High-throughput

0.437

High

997175

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

5

High-throughput

0.437

High

1057175

MELK
Maternal embryonic leucine zipper kinase

1

2

High-throughput

0.437

High

1060555

ZN638
Zinc finger protein 638

1

5

High-throughput

0.437

High

1076884

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

19

High-throughput

0.437

High

1084062

OCLN
Occludin

1

4

High-throughput

0.437

High

1136516

SPD2A
SH3 and PX domain-containing protein 2A

1

20

High-throughput

0.437

High

1137516

RIF1
Telomere-associated protein RIF1

1

3

High-throughput

0.437

High

1139608

DEN4C
DENN domain-containing protein 4C

1

7

High-throughput

0.437

High

1146538

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.437

High

1148991

AN34A
Ankyrin repeat domain-containing protein 34A

1

13

High-throughput

0.437

High

1153266

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.437

High

1170519

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1173127

KSR1
Kinase suppressor of Ras 1

1

18

High-throughput

0.437

High

1173130

ARL14
ADP-ribosylation factor-like protein 14

1

10

High-throughput

0.437

High

1173131

NAV1
Neuron navigator 1

1

4

High-throughput

0.437

High

1173132

F110B
Protein FAM110B

1

3

High-throughput

0.437

High

1173133

DEN1A
DENN domain-containing protein 1A

1

7

High-throughput

0.437

High

1173135

SRS12
Serine/arginine-rich splicing factor 12

1

8

High-throughput

0.437

High

1173139

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.437

High

1173141

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.437

High

1173144

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

1

High-throughput

0.437

High

1173145

F110A
Protein FAM110A

1

3

High-throughput

0.437

High

1173148

WDR33
pre-mRNA 3' end processing protein WDR33

1

5

High-throughput

0.437

High

1173149

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.437

High

1173151

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.437

High

1173154

FA53C
Protein FAM53C

1

1

High-throughput

0.437

High

1173155

SH3B4
SH3 domain-binding protein 4

1

1

High-throughput

0.437

High

1173156

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

2

High-throughput

0.437

High

1173157

CING
Cingulin

1

5

High-throughput

0.437

High

1173161

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

3

High-throughput

0.437

High

1173162

ZBT21
Zinc finger and BTB domain-containing protein 21

1

13

High-throughput

0.437

High

1173163

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.437

High

1173168

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.437

High

1173169

KCTD3
BTB/POZ domain-containing protein KCTD3

1

4

High-throughput

0.437

High

483941

CALM1
Calmodulin-1

1

7

High-throughput

0.407

High

181430

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

0

High-throughput

0.328

High

624942

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.328

High

738852

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

0

High-throughput

0.328

High

854435

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

0

High-throughput

0.328

High

1153127

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

0

High-throughput

0.328

High

1173129

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.328

High

428727

TRY2
Trypsin-2

2

0

High-throughput

0.298

High

1173159

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024