Protein: AFG2A
ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5)

Gene: AFG2A
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q8NB90

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1239601

AFG2B
ATPase family gene 2 protein homolog B

3

17

High-throughput

0.861

High

228067

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.754

High

798714

PRS6B
26S proteasome regulatory subunit 6B

1

10

High-throughput

0.691

High

907100

PRS8
26S proteasome regulatory subunit 8

1

15

High-throughput

0.691

High

1239602

CINP
Cyclin-dependent kinase 2-interacting protein

3

1

High-throughput

0.667

High

1239615

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.631

High

656272

PSA5
Proteasome subunit alpha type-5

1

7

Small-scale

0.618

High

1239586

AFG2A
ATPase family gene 2 protein homolog A

1

16

High-throughput

0.618

High

1239604

Q9H4D1
Protein kinase

1

7

High-throughput

0.618

High

1239609

ATD3A
ATPase family AAA domain-containing protein 3A

1

18

High-throughput

0.618

High

632331

TNR6
Tumor necrosis factor receptor superfamily member 6

2

4

High-throughput

0.611

High

883564

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

7

High-throughput

0.575

High

1239616

DKKL1
Dickkopf-like protein 1

2

3

High-throughput

0.574

High

370020

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1145843

CP135
Centrosomal protein of 135 kDa

2

4

High-throughput

0.571

High

1239618

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.553

High

130996

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

5

High-throughput

0.536

High

163009

XPO1
Exportin-1

1

6

High-throughput

0.536

High

529419

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

642459

RL13
Large ribosomal subunit protein eL13

1

5

High-throughput

0.536

High

642968

S10A4
Protein S100-A4

1

2

High-throughput

0.536

High

796610

KSYK
Tyrosine-protein kinase SYK

1

2

High-throughput

0.536

High

899269

RL15
Large ribosomal subunit protein eL15

1

2

High-throughput

0.536

High

919169

RAN
GTP-binding nuclear protein Ran

1

8

High-throughput

0.536

High

1039695

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

1233099

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

1077031

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1239598

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

902675

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

411439

INSR
Insulin receptor

1

3

High-throughput

0.500

High

126621

P2Y10
Putative P2Y purinoceptor 10

1

3

High-throughput

0.489

High

795374

SSRB
Translocon-associated protein subunit beta

1

1

High-throughput

0.489

High

1205534

TMM25
Transmembrane protein 25

1

2

High-throughput

0.489

High

1239588

F174A
Membrane protein FAM174A

1

3

High-throughput

0.489

High

1239595

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

1

High-throughput

0.489

High

1239620

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

3

High-throughput

0.489

High

1239622

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

122883

MEN1
Menin

1

2

High-throughput

0.479

High

149060

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

164428

TRI66
Tripartite motif-containing protein 66

1

7

High-throughput

0.479

High

182828

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

298654

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

303360

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

319271

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.479

High

325278

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.479

High

347346

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

385172

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

442315

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

5

High-throughput

0.479

High

504410

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

598233

FLNA
Filamin-A

1

2

High-throughput

0.479

High

617334

SP100
Nuclear autoantigen Sp-100

1

2

High-throughput

0.479

High

742405

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

749683

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

779748

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

861847

PLK1
Serine/threonine-protein kinase PLK1

1

10

High-throughput

0.479

High

917605

H4
Histone H4

1

2

High-throughput

0.479

High

1042056

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1043962

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.479

High

1064493

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1085829

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.479

High

1101169

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1146624

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

1170836

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1232544

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.479

High

1236377

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1239587

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1239589

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1239591

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1239594

AURKB
Aurora kinase B

1

6

High-throughput

0.479

High

1239596

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1239599

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

1239603

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

5

High-throughput

0.479

High

1239605

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

1239606

BRD7
Bromodomain-containing protein 7

1

9

High-throughput

0.479

High

1239607

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1239608

ANLN
Anillin

1

3

High-throughput

0.479

High

1239611

AIRIM
AFG2-interacting ribosome maturation factor

1

1

High-throughput

0.479

High

1239613

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1239617

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

1239619

FBW1A
F-box/WD repeat-containing protein 1A

1

11

High-throughput

0.479

High

1239593

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1239612

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1239614

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.458

High

1239592

ESR2
Estrogen receptor beta

1

10

High-throughput

0.445

High

100962

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

1052563

RCN2
Reticulocalbin-2

1

3

High-throughput

0.437

High

1053606

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1160317

CF161
Cilia- and flagella-associated protein 161

1

1

High-throughput

0.437

High

1239590

DNS2B
Deoxyribonuclease-2-beta

1

1

High-throughput

0.437

High

1239597

RCC1L
RCC1-like G exchanging factor-like protein

1

4

High-throughput

0.437

High

1239600

ZFY21
Zinc finger FYVE domain-containing protein 21

1

1

Small-scale

0.437

High

1239610

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

Small-scale

0.437

High

1089451

Q17RG0
ATG16L1 protein

1

9

High-throughput

0.407

High

1239621

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024