Protein: UBA3
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)

Gene: UBA3
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q8TBC4

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896154

UBC12
NEDD8-conjugating enzyme Ubc12

19

20

Small-scale

0.988

High

1039432

ULA1
NEDD8-activating enzyme E1 regulatory subunit

11

13

Small-scale

0.974

High

1252654

UBE2F
NEDD8-conjugating enzyme UBE2F

5

20

Small-scale

0.914

High

1252652

UBA3
NEDD8-activating enzyme E1 catalytic subunit

4

11

Small-scale

0.898

High

1079547

NEDD8
NEDD8

4

6

Small-scale

0.890

High

228127

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.754

High

1252657

CPNE2
Copine-2

3

2

High-throughput

0.675

High

919796

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.647

High

153024

IMPA2
Inositol monophosphatase 2

3

0

High-throughput

0.646

High

1252658

MTNB
Methylthioribulose-1-phosphate dehydratase

3

0

High-throughput

0.638

High

872191

RD23A
UV excision repair protein RAD23 homolog A

1

8

Small-scale

0.618

High

872288

RD23B
UV excision repair protein RAD23 homolog B

1

11

Small-scale

0.618

High

1241821

ZBT44
Zinc finger and BTB domain-containing protein 44

2

1

High-throughput

0.611

High

1252661

DUS23
Dual specificity protein phosphatase 23

2

5

High-throughput

0.606

High

1240878

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.536

High

1252656

OPTN
Optineurin

1

1

High-throughput

0.536

High

1252659

FA81B
Protein FAM81B

1

1

High-throughput

0.536

High

1252666

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.536

High

1018599

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.518

High

1252660

UIMC1
BRCA1-A complex subunit RAP80

1

1

High-throughput

0.515

High

395279

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.515

High

238593

MUSC
Musculin

1

0

High-throughput

0.513

High

1063508

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.513

High

175061

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

1252653

CUL5
Cullin-5

1

4

Small-scale

0.501

High

361506

APOE
Apolipoprotein E

1

0

High-throughput

0.493

High

1121784

ANR39
Ankyrin repeat domain-containing protein 39

1

4

High-throughput

0.489

High

1252663

LRTM1
Leucine-rich repeat and transmembrane domain-containing protein 1

1

1

High-throughput

0.489

High

232355

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

1252655

TRI63
E3 ubiquitin-protein ligase TRIM63

1

11

High-throughput

0.481

High

1252662

TRI55
Tripartite motif-containing protein 55

1

13

High-throughput

0.481

High

1252664

RBX2
RING-box protein 2

1

0

Small-scale

0.480

High

374576

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

402269

JUN
Transcription factor Jun

1

8

High-throughput

0.479

High

673091

CCND2
G1/S-specific cyclin-D2

1

1

Small-scale

0.479

High

795777

MAGA3
Melanoma-associated antigen 3

1

2

Small-scale

0.479

High

1170924

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1252665

HERC5
E3 ISG15--protein ligase HERC5

1

11

Small-scale

0.479

High

360192

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

719556

MERL
Merlin

1

0

High-throughput

0.458

High

378109

PRIO
Major prion protein

1

2

High-throughput

0.445

High

100985

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

720970

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

234554

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

571173

EGLN
Endoglin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024