Protein: EDA
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]

Gene: EDA
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q92838

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005123 - death receptor binding
GO:0005164 - tumor necrosis factor receptor binding
GO:0005581 - collagen trimer
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644415

PPLA
Cardiac phospholamban

6

0

High-throughput

0.710

High

873299

EMP3
Epithelial membrane protein 3

4

2

High-throughput

0.698

High

1271580

SC22A
Vesicle-trafficking protein SEC22a

4

1

High-throughput

0.698

High

307719

LERL1
Leptin receptor overlapping transcript-like 1

4

1

High-throughput

0.683

High

596914

MAL
Myelin and lymphocyte protein

4

0

High-throughput

0.668

High

1159620

NPAL3
NIPA-like protein 3

4

0

High-throughput

0.668

High

120012

AP3B1
AP-3 complex subunit beta-1

3

2

High-throughput

0.667

High

274437

CRTAP
Cartilage-associated protein

3

7

High-throughput

0.667

High

788055

AF9
Protein AF-9

3

1

High-throughput

0.667

High

963951

IL9R
Interleukin-9 receptor

3

2

High-throughput

0.667

High

1104071

P3H1
Prolyl 3-hydroxylase 1

3

7

High-throughput

0.667

High

1114512

ZACN
Ligand-gated cation channel ZACN

3

5

High-throughput

0.667

High

1160157

S39A4
Zinc transporter ZIP4

3

1

High-throughput

0.667

High

1217648

P3H2
Prolyl 3-hydroxylase 2

3

7

High-throughput

0.667

High

1271601

CIZ1
Cip1-interacting zinc finger protein

3

5

High-throughput

0.667

High

1271575

EDA
Ectodysplasin-A

1

17

Small-scale

0.647

High

828125

CY561
Transmembrane ascorbate-dependent reductase CYB561

3

0

High-throughput

0.646

High

1271603

DOLK
Dolichol kinase

3

0

High-throughput

0.646

High

216560

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

0

High-throughput

0.638

High

849567

GPM6A
Neuronal membrane glycoprotein M6-a

3

0

High-throughput

0.638

High

1114047

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

3

0

High-throughput

0.638

High

1271585

OSBL8
Oxysterol-binding protein-related protein 8

3

0

High-throughput

0.638

High

1271586

LNP
Endoplasmic reticulum junction formation protein lunapark

3

0

High-throughput

0.638

High

1271589

PININ
Pinin

3

0

High-throughput

0.638

High

1271609

ALG5
Dolichyl-phosphate beta-glucosyltransferase

3

0

High-throughput

0.638

High

1271610

TX264
Testis-expressed protein 264

3

0

High-throughput

0.638

High

439250

MMP2
72 kDa type IV collagenase

2

17

High-throughput

0.628

High

687006

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

4

High-throughput

0.628

High

723365

APJ
Apelin receptor

2

1

High-throughput

0.628

High

793200

PI2R
Prostacyclin receptor

2

2

High-throughput

0.628

High

1083473

C3AR
C3a anaphylatoxin chemotactic receptor

2

3

High-throughput

0.628

High

1271582

GPR21
Probable G-protein coupled receptor 21

2

2

High-throughput

0.628

High

1271598

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

2

High-throughput

0.628

High

1271608

PCDC2
Protocadherin alpha-C2

2

1

High-throughput

0.628

High

1263258

5HT3C
5-hydroxytryptamine receptor 3C

2

4

High-throughput

0.611

High

179054

TNC18
Trinucleotide repeat-containing gene 18 protein

3

3

High-throughput

0.609

High

567738

UBF1
Nucleolar transcription factor 1

3

3

High-throughput

0.609

High

864053

AP3M2
AP-3 complex subunit mu-2

3

1

High-throughput

0.609

High

1032732

AP3B2
AP-3 complex subunit beta-2

3

2

High-throughput

0.609

High

1166132

CWC27
Spliceosome-associated protein CWC27 homolog

3

1

High-throughput

0.609

High

1262033

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

2

High-throughput

0.609

High

1271590

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

1

High-throughput

0.609

High

1271605

AP3M1
AP-3 complex subunit mu-1

3

1

High-throughput

0.609

High

873255

EMP1
Epithelial membrane protein 1

2

2

High-throughput

0.606

High

964843

PMP22
Peripheral myelin protein 22

2

2

High-throughput

0.606

High

1271599

LPAR3
Lysophosphatidic acid receptor 3

2

1

High-throughput

0.606

High

1259424

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

0

High-throughput

0.602

High

648057

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.601

High

1133449

UBR4
E3 ubiquitin-protein ligase UBR4

2

0

High-throughput

0.585

High

881483

TM50B
Transmembrane protein 50B

2

0

High-throughput

0.580

High

1117642

CTXN3
Cortexin-3

2

0

High-throughput

0.580

High

1126721

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

1148553

TMM42
Transmembrane protein 42

2

0

High-throughput

0.580

High

1271588

TMM60
Transmembrane protein 60

2

0

High-throughput

0.580

High

1271593

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

1

High-throughput

0.573

High

1271602

EDAR
Tumor necrosis factor receptor superfamily member EDAR

2

0

Small-scale

0.559

High

1271600

AFF4
AF4/FMR2 family member 4

2

4

High-throughput

0.558

High

1271604

SRRM2
Serine/arginine repetitive matrix protein 2

2

2

High-throughput

0.558

High

1271594

S38A7
Sodium-coupled neutral amino acid transporter 7

2

1

High-throughput

0.553

High

506340

ACHB
Acetylcholine receptor subunit beta

1

4

High-throughput

0.536

High

532183

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

4

High-throughput

0.536

High

621351

FSHR
Follicle-stimulating hormone receptor

1

3

High-throughput

0.536

High

677159

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

4

High-throughput

0.536

High

713676

GBRA3
Gamma-aminobutyric acid receptor subunit alpha-3

1

2

High-throughput

0.536

High

798549

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

3

High-throughput

0.536

High

989638

ACHD
Acetylcholine receptor subunit delta

1

4

High-throughput

0.536

High

1031034

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.536

High

1271583

CIB1
Calcium and integrin-binding protein 1

1

1

High-throughput

0.536

High

1271587

S39A8
Metal cation symporter ZIP8

1

1

High-throughput

0.536

High

1271607

PCDB1
Protocadherin beta-1

1

1

High-throughput

0.536

High

1151050

Q6FHL7
Leptin receptor overlapping transcript-like 1

1

1

High-throughput

0.515

High

354874

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.513

High

885944

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.513

High

944149

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

0

High-throughput

0.513

High

946422

EREP3
Protein ENTREP3

1

0

High-throughput

0.513

High

1239943

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1255793

TS1R2
Taste receptor type 1 member 2

1

0

High-throughput

0.513

High

1271577

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

1271578

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

1271591

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

0

High-throughput

0.513

High

1271595

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.513

High

1126226

RABL3
Rab-like protein 3

1

1

High-throughput

0.489

High

1245830

RASF8
Ras association domain-containing protein 8

1

1

High-throughput

0.489

High

312348

IPO7
Importin-7

1

1

High-throughput

0.479

High

1271592

JPH1
Junctophilin-1

1

1

High-throughput

0.479

High

1271596

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

1

High-throughput

0.479

High

1253098

Q8TBU1
Oligosaccharyltransferase complex subunit

1

1

High-throughput

0.470

High

757700

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

101029

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

1271576

GIMA5
GTPase IMAP family member 5

3

0

High-throughput

0.352

High

165706

SET1A
Histone-lysine N-methyltransferase SETD1A

3

0

High-throughput

0.347

High

1271579

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

3

0

High-throughput

0.347

High

1271597

CXXC1
CXXC-type zinc finger protein 1

3

0

High-throughput

0.347

High

828854

SRP09
Signal recognition particle 9 kDa protein

2

0

High-throughput

0.328

High

1199581

SO6A1
Solute carrier organic anion transporter family member 6A1

2

0

High-throughput

0.328

High

1070579

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.249

Low

1271581

SIN3A
Paired amphipathic helix protein Sin3a

1

0

High-throughput

0.249

Low

1271584

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

High-throughput

0.249

Low

1271606

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024