Protein: CK5P3
CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27)

Gene: CK5P3, CDK5RAP3
Organism: Homo sapiens
Interactions: 173
UniProt ID: Q96JB5

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001889 - liver development
GO:0001933 - negative regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

298724

UFL1
E3 UFM1-protein ligase 1

9

2

Small-scale

0.756

High

1293910

DDRGK
DDRGK domain-containing protein 1

7

2

Small-scale

0.744

High

259965

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

5

1

High-throughput

0.726

High

1295051

SRPRB
Signal recognition particle receptor subunit beta

4

0

High-throughput

0.663

High

1295041

TSYL4
Testis-specific Y-encoded-like protein 4

3

0

High-throughput

0.646

High

1295048

UFC1
Ubiquitin-fold modifier-conjugating enzyme 1

3

0

Small-scale

0.645

High

790849

CDN2A
Cyclin-dependent kinase inhibitor 2A

3

0

Small-scale

0.633

High

833300

TMEDA
Transmembrane emp24 domain-containing protein 10

2

4

High-throughput

0.628

High

1295036

PD1L1
Programmed cell death 1 ligand 1

3

1

High-throughput

0.609

High

159391

PLD2
Phospholipase D2

2

0

High-throughput

0.602

High

1288774

TRI44
Tripartite motif-containing protein 44

2

0

High-throughput

0.602

High

228370

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

714361

HSP74
Heat shock 70 kDa protein 4

2

1

Small-scale

0.584

High

1034801

TMED1
Transmembrane emp24 domain-containing protein 1

2

5

High-throughput

0.574

High

1192848

TMED4
Transmembrane emp24 domain-containing protein 4

2

3

High-throughput

0.574

High

370211

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1295031

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.565

High

902846

UFM1
Ubiquitin-fold modifier 1

2

0

Small-scale

0.563

High

890350

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

962920

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

Small-scale

0.559

High

158110

TX1B3
Tax1-binding protein 3

1

0

Small-scale

0.549

High

1071812

TMED2
Transmembrane emp24 domain-containing protein 2

1

5

High-throughput

0.536

High

1078226

CD226
CD226 antigen

1

3

High-throughput

0.536

High

1295019

TMPSD
Transmembrane protease serine 13

1

3

High-throughput

0.536

High

388656

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

1050884

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.518

High

258148

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

439849

NEP
Neprilysin

1

0

Small-scale

0.513

High

639048

S100P
Protein S100-P

1

0

High-throughput

0.513

High

801308

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1077077

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1150123

ZN787
Zinc finger protein 787

1

0

High-throughput

0.513

High

1154321

B4GN3
Beta-1,4-N-acetylgalactosaminyltransferase 3

1

0

High-throughput

0.513

High

1167733

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

0

High-throughput

0.513

High

1202531

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1218905

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1282465

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1282591

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

1283236

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1295022

REN3A
Regulator of nonsense transcripts 3A

1

0

High-throughput

0.513

High

1295028

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.513

High

445869

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

6

High-throughput

0.500

High

278963

SPF30
Survival of motor neuron-related-splicing factor 30

1

0

High-throughput

0.493

High

671896

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.493

High

776173

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.493

High

837157

KHK
Ketohexokinase

1

0

High-throughput

0.493

High

978853

TF65
Transcription factor p65

1

0

Small-scale

0.493

High

1295018

TMED9
Transmembrane emp24 domain-containing protein 9

1

3

High-throughput

0.489

High

1295047

TMED5
Transmembrane emp24 domain-containing protein 5

1

5

High-throughput

0.489

High

1077930

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.481

High

1067691

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

Small-scale

0.480

High

178727

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

331324

CHK2
Serine/threonine-protein kinase Chk2

1

1

Small-scale

0.479

High

338843

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

383934

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

5

High-throughput

0.479

High

411471

INSR
Insulin receptor

1

7

High-throughput

0.479

High

435732

IGF1R
Insulin-like growth factor 1 receptor

1

7

High-throughput

0.479

High

452470

PGFRB
Platelet-derived growth factor receptor beta

1

4

High-throughput

0.479

High

508151

FGFR1
Fibroblast growth factor receptor 1

1

5

High-throughput

0.479

High

542415

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

567221

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

591657

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.479

High

592438

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

729336

VGFR3
Vascular endothelial growth factor receptor 3

1

4

High-throughput

0.479

High

845169

RAB7A
Ras-related protein Rab-7a

1

2

High-throughput

0.479

High

845669

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

1017755

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1053133

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1081568

NTRK3
NT-3 growth factor receptor

1

6

High-throughput

0.479

High

1146735

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1198655

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.479

High

1204813

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.479

High

1240726

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1269366

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1295014

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1295032

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

1295043

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1295044

ALK
ALK tyrosine kinase receptor

1

6

High-throughput

0.479

High

772116

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

853427

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.460

High

1288149

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.460

High

154230

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.458

High

163936

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

175395

PPM1D
Protein phosphatase 1D

1

0

Small-scale

0.458

High

268513

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

273941

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

364720

TRFL
Lactotransferrin

1

0

High-throughput

0.458

High

390458

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

391104

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

418551

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

456915

FURIN
Furin

1

0

High-throughput

0.458

High

476207

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

504581

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.458

High

507184

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

573858

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

595359

LMNB1
Lamin-B1

1

0

High-throughput

0.458

High

614099

TBG1
Tubulin gamma-1 chain

1

0

Small-scale

0.458

High

616466

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

648852

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

651967

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

654667

CALX
Calnexin

1

0

High-throughput

0.458

High

726361

BASI
Basigin

1

0

High-throughput

0.458

High

786081

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

795237

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

839051

EMD
Emerin

1

0

High-throughput

0.458

High

847608

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

900804

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

914282

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

922665

RL10A
Large ribosomal subunit protein uL1

1

0

Small-scale

0.458

High

940527

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

966626

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.458

High

990615

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1029744

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1035548

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1077456

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

1082614

MK14
Mitogen-activated protein kinase 14

1

0

Small-scale

0.458

High

1171257

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1192171

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

Small-scale

0.458

High

1240254

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1242632

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

0

Small-scale

0.458

High

1284010

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1295015

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1295016

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1295017

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1295020

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1295021

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

1295025

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.458

High

1295027

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1295029

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1295030

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1295033

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1295034

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1295035

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1295037

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1295038

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1295039

DMBT1
Deleted in malignant brain tumors 1 protein

1

0

High-throughput

0.458

High

1295040

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1295042

WWC3
Protein WWC3

1

0

High-throughput

0.458

High

1295049

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

1295050

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

177971

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.437

High

354115

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.437

High

434264

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

5

High-throughput

0.437

High

591976

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

665515

EPHA8
Ephrin type-A receptor 8

1

2

High-throughput

0.437

High

872471

EPHA5
Ephrin type-A receptor 5

1

3

High-throughput

0.437

High

968460

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

5

High-throughput

0.437

High

1153724

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.437

High

1198134

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.437

High

1230331

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1263884

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1295023

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

1039148

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.426

High

1295045

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1233664

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

3

0

Small-scale

0.347

High

1237311

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1295026

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.328

High

300682

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

856447

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1083242

CART

1

0

High-throughput

0.279

Low

1166255

AMTN
Amelotin

1

0

High-throughput

0.279

Low

1205229

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

1245426

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.279

Low

1295046

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.279

Low

1295052

IRAG1
Inositol 1,4,5-triphosphate receptor associated 1

1

0

High-throughput

0.279

Low

101070

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

353552

IGKC
Immunoglobulin kappa constant

1

0

High-throughput

0.249

Low

719762

RADI
Radixin

1

0

High-throughput

0.249

Low

877526

CADH4
Cadherin-4

1

0

Small-scale

0.249

Low

961781

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

1040218

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1246399

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

Small-scale

0.249

Low

1295024

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024