Protein: PURB
Transcriptional regulator protein Pur-beta (Purine-rich element-binding protein B)

Gene: PURB
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q96QR8

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003697 - single-stranded DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1300546

PURG
Purine-rich element-binding protein gamma

1

5

High-throughput

0.691

High

445496

RSSA
Small ribosomal subunit protein uS2

3

2

High-throughput

0.667

High

1116471

LARP7
La-related protein 7

3

7

High-throughput

0.656

High

916782

RS6
Small ribosomal subunit protein eS6

3

2

High-throughput

0.650

High

550914

RS2
Small ribosomal subunit protein uS5

3

0

High-throughput

0.638

High

1300545

CNOT7
CCR4-NOT transcription complex subunit 7

3

0

High-throughput

0.638

High

370247

ESR1
Estrogen receptor

3

5

High-throughput

0.633

High

608615

H1T
Histone H1t

2

8

High-throughput

0.628

High

1065865

RRS1
Ribosome biogenesis regulatory protein homolog

2

2

High-throughput

0.628

High

1300539

H2AW
Core histone macro-H2A.2

2

5

High-throughput

0.628

High

391851

H2A1B
Histone H2A type 1-B/E

2

4

High-throughput

0.611

High

718123

BMI1
Polycomb complex protein BMI-1

2

2

High-throughput

0.611

High

1169386

ZN497
Zinc finger protein 497

2

6

High-throughput

0.606

High

1300536

LN28A
Protein lin-28 homolog A

2

11

High-throughput

0.601

High

1284205

SOSB2
SOSS complex subunit B2

2

0

High-throughput

0.580

High

1300542

MBD2
Methyl-CpG-binding domain protein 2

2

0

High-throughput

0.580

High

1054083

GRB7
Growth factor receptor-bound protein 7

2

3

High-throughput

0.571

High

1269410

ESR2
Estrogen receptor beta

2

5

High-throughput

0.571

High

408662

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

934408

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.545

High

180421

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.536

High

269848

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

8

High-throughput

0.536

High

281385

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.536

High

401053

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.536

High

489215

H14
Histone H1.4

1

8

High-throughput

0.536

High

529597

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

559902

H12
Histone H1.2

1

8

High-throughput

0.536

High

616473

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

642531

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

736666

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

759786

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

790518

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

796634

KSYK
Tyrosine-protein kinase SYK

1

2

High-throughput

0.536

High

801322

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

807491

RS10
Small ribosomal subunit protein eS10

1

2

High-throughput

0.536

High

907462

RS8
Small ribosomal subunit protein eS8

1

2

High-throughput

0.536

High

913699

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.536

High

916325

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

922322

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.536

High

931352

YBOX1
Y-box-binding protein 1

1

10

High-throughput

0.536

High

942885

SRPK2
SRSF protein kinase 2

1

10

High-throughput

0.536

High

1040650

KRR1
KRR1 small subunit processome component homolog

1

2

High-throughput

0.536

High

1042333

CUL3
Cullin-3

1

3

High-throughput

0.536

High

1076092

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

1193019

ZN467
Zinc finger protein 467

1

7

High-throughput

0.536

High

1272761

FGF13
Fibroblast growth factor 13

1

1

High-throughput

0.536

High

1291162

NEIL1
Endonuclease 8-like 1

1

1

High-throughput

0.536

High

1300530

UTP23
rRNA-processing protein UTP23 homolog

1

1

High-throughput

0.536

High

1300547

ZN346
Zinc finger protein 346

1

2

High-throughput

0.536

High

1300548

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1300551

YBOX2
Y-box-binding protein 2

1

10

High-throughput

0.536

High

1300544

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.515

High

739809

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

1176060

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.513

High

1300532

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

3

High-throughput

0.500

High

198962

RFOX2
RNA binding protein fox-1 homolog 2

1

4

High-throughput

0.481

High

326755

SNAI1
Zinc finger protein SNAI1

1

7

High-throughput

0.479

High

347645

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

374727

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

379757

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

442412

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

472920

H2AB2
Histone H2A-Bbd type 2/3

1

6

High-throughput

0.479

High

707716

H2B1B
Histone H2B type 1-B

1

1

High-throughput

0.479

High

726999

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

760248

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

890807

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

898715

RL26
Large ribosomal subunit protein uL24

1

1

High-throughput

0.479

High

908983

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

917778

H4
Histone H4

1

1

High-throughput

0.479

High

959618

VIGLN
Vigilin

1

4

High-throughput

0.479

High

998993

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1018009

GRSF1
G-rich sequence factor 1

1

5

High-throughput

0.479

High

1025915

TADBP
TAR DNA-binding protein 43

1

4

High-throughput

0.479

High

1030428

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

1136239

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1168935

LN28B
Protein lin-28 homolog B

1

11

High-throughput

0.479

High

1184278

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

1199389

LYRIC
Protein LYRIC

1

1

Small-scale

0.479

High

1201612

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

1237453

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1300528

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1300529

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

1300533

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.479

High

1300537

RC3H2
Roquin-2

1

3

High-throughput

0.479

High

1300540

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.479

High

1300543

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.460

High

303431

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

553486

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652009

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721209

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

1300538

ANLN
Anillin

1

0

High-throughput

0.458

High

497464

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

920890

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

1

High-throughput

0.445

High

1300549

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.445

High

101096

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

738258

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.437

High

1171319

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1198142

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1300534

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

1300535

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

883608

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1255802

Q8TE30
RNA-directed DNA polymerase

1

1

Small-scale

0.407

High

831608

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1252422

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.316

High

1300531

AP1M1
AP-1 complex subunit mu-1

2

0

High-throughput

0.316

High

1300552

PCDBE
Protocadherin beta-14

2

0

High-throughput

0.316

High

410584

CD1A
T-cell surface glycoprotein CD1a

1

0

High-throughput

0.279

Low

615461

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

686727

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

1245416

O52K2
Olfactory receptor 52K2

1

0

High-throughput

0.279

Low

391114

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1061566

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1300550

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.249

Low

1300541

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024